Patents by Inventor Mark J. Brierton

Mark J. Brierton has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190201916
    Abstract: Systems and methods are provided for separating blood into two or more components. A blood separation system includes a blood separation device and a fluid flow circuit configured to be mounted to the blood separation device. The blood separation device includes a centrifugal separator and a spinning membrane separator drive unit incorporated into a common case, which allows for fluid separation by two different methods. Depending on the separation procedure to be carried out, the fluid flow circuit paired with the blood separation device may include only one separation chamber configured to be mounted to the centrifugal separator or spinning membrane separator drive unit or two separation chambers, with one being mounted to the centrifugal separator and the other to the spinning membrane separator drive unit. The system may be used to separate and collect any combination of red blood cells, plasma, and platelets.
    Type: Application
    Filed: September 15, 2017
    Publication date: July 4, 2019
    Inventors: Kyungyoon Min, Benjamin E. Kusters, Richard I. Brown, Mark J. Brierton
  • Publication number: 20180311430
    Abstract: A fluid flow circuit assembly for a fluid processing device, comprising a housing having a plurality of openings, a separator disposed at least partially within the housing, and a plurality of flow paths communicating between an interior and an exterior of the housing via the plurality of openings, wherein the separator is disposed substantially at the center of the plurality of flow paths.
    Type: Application
    Filed: October 13, 2016
    Publication date: November 1, 2018
    Inventors: Benjamin E. Kusters, Mark J. Brierton
  • Publication number: 20180010612
    Abstract: A disposable fluid pump is provided with a housing including first and second faces, with a sidewall extending between the first and second faces. The housing defines a chamber, with an inlet and an outlet in fluid communication with the chamber. An impeller is rotatably mounted within the chamber and includes a plurality of flexible vanes. Such a pump may be incorporated into a disposable fluid flow circuit that is adapted to be mounted on a durable hardware for processing a fluid. In such a fluid flow circuit, the fluid pump may be integrated into a cassette of the circuit or, alternatively, the inlet and outlet of the fluid pump may be directly connected to fluid flow conduits of the circuit.
    Type: Application
    Filed: July 7, 2017
    Publication date: January 11, 2018
    Inventors: Christopher J. Wegener, Mark J. Brierton
  • Patent number: 9421318
    Abstract: The present disclosure relates generally to systems for processing a unit of whole blood into its components while the unit is still in the centrifuge. The system comprises a container holding whole blood and one or more satellite bags or containers that are installed into a holder, which is then inserted into a bucket of the centrifuge. Tubes interconnect the containers, one or more of which are preferably installed into clamping mechanisms resident in the holder. The holder further preferably includes sensing means, such as optical sensors, to sense the location of the interfaces between the separated layers of the whole blood that result from rotation of the centrifuge.
    Type: Grant
    Filed: October 24, 2012
    Date of Patent: August 23, 2016
    Assignee: Fenwal, Inc.
    Inventors: Marc N. Weasler, Richard I. Brown, Sean Ford, Mark J. Brierton
  • Patent number: 9408961
    Abstract: A membrane separation device is disclosed along with systems and methods employing the device in blood processing procedures. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib associated with the membrane that decreases the gap between the membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously collected whole blood into components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: August 9, 2016
    Assignee: Fenwal, Inc.
    Inventors: Christopher J. Wegener, Kyungyoon Min, Laurent Forcioli, Mark J. Brierton, Daniel R. Boggs
  • Patent number: 9381291
    Abstract: A membrane separation device for use in blood processing procedures is disclosed. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the spinning membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib or ridge associated with the spinning membrane that decreases the gap between the spinning membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously collected whole blood into selected blood components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed.
    Type: Grant
    Filed: March 9, 2012
    Date of Patent: July 5, 2016
    Assignee: Fenwal, Inc.
    Inventors: Daniel R. Boggs, Mark J. Brierton, Benjamin E. Kusters, Kyungyoon Min, Christopher J. Wegener
  • Publication number: 20140066281
    Abstract: The present disclosure relates generally to systems for processing a unit of whole blood into its components while the unit is still in the centrifuge. The system comprises a container holding whole blood and one or more satellite bags or containers that are installed into a holder, which is then inserted into a bucket of the centrifuge. Tubes interconnect the containers, one or more of which are preferably installed into clamping mechanisms resident in the holder. The holder further preferably includes sensing means, such as optical sensors, to sense the location of the interfaces between the separated layers of the whole blood that result from rotation of the centrifuge.
    Type: Application
    Filed: October 24, 2012
    Publication date: March 6, 2014
    Inventors: Marc N. Weasler, Richard I. Brown, Sean Ford, Mark J. Brierton
  • Publication number: 20140010738
    Abstract: A membrane separation device for use in blood processing procedures is disclosed. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the spinning membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib or ridge associated with the spinning membrane that decreases the gap between the spinning membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously collected whole blood into selected blood components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed.
    Type: Application
    Filed: March 9, 2012
    Publication date: January 9, 2014
    Applicant: FENWAL INC.
    Inventors: Daniel R. Boggs, Mark J. Brierton, Benjamin E. Kusters, Kyungyoon Min, Christopher J. Wegener
  • Publication number: 20130341291
    Abstract: A membrane separation device is disclosed along with systems and methods employing the device in blood processing procedures. In one embodiment, a spinning membrane separator is provided in which at least two zones or regions are created in the gap between the membrane and the shell, such that mixing of the fluid between the two regions is inhibited by a radial rib associated with the membrane that decreases the gap between the membrane and the shell to define two fluid regions, the ridge isolating the fluid in the two regions to minimize mixing between the two. Automated systems and methods are disclosed for separating a unit of previously collected whole blood into components, such as concentrated red cells and plasma, for collecting red cells and plasma directly from a donor in a single pass, and for cell washing. Data management systems and methods and priming methods are also disclosed.
    Type: Application
    Filed: March 9, 2012
    Publication date: December 26, 2013
    Applicant: FENWAL, INC.
    Inventors: Christopher J. Wegener, Kyungyoon Min, Laurent Forcioli, Mark J. Brierton, Daniel R. Boggs
  • Publication number: 20110086752
    Abstract: A blood separation chamber for rotation about an axis comprises a low-G wall and a high-G wall extending about the axis in a spaced apart relationship to define between them a separation channel. The separation channel includes axially spaced first and second ends. The first end of the separation channel defines at least one generally arcuate recessed region and at least one radial wall within the recessed region sized and positioned so as to aid in balancing the blood separation chamber during rotation about the axis.
    Type: Application
    Filed: October 8, 2009
    Publication date: April 14, 2011
    Inventor: Mark J. Brierton
  • Patent number: 6409696
    Abstract: An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various aspects of the apheresis procedure. Moreover, the system also includes a variety of features relating to loading a blood processing vessel into a blood processing channel and removing the same after completion of the procedure. Furthermore, the system also includes a variety of features relating to utilizing a blood priming of at least portions of the apheresis system in preparation for the procedure. In addition, the system includes a variety of features enhancing the performance of the apheresis system, including the interrelationship between the blood processing vessel and the blood processing vessel and the utilization of high packing factors for the procedure.
    Type: Grant
    Filed: October 10, 1997
    Date of Patent: June 25, 2002
    Assignee: Gambro, Inc.
    Inventors: Coy Toavs, John J. Kappus, Mark J. Brierton, David R. Shouldice, Jeffrey J. Blakeslee
  • Patent number: 6361518
    Abstract: An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various aspects of the apheresis procedure. Moreover, the system also includes a variety of features relating to loading a blood processing vessel into a blood processing channel and removing the same after completion of the procedure. Furthermore, the system also includes a variety of features relating to utilizing a blood priming of at least portions of the apheresis system in preparation for the procedure. In addition, the system includes a variety of features enhancing the performance of the apheresis system, including the interrelationship between the blood processing vessel and the blood processing vessel and the utilization of high packing factors for the procedure.
    Type: Grant
    Filed: April 28, 1998
    Date of Patent: March 26, 2002
    Assignee: Gambro Inc.
    Inventors: Mark J. Brierton, Victor D. Dolecek, Leon E. Bilodeau, Russell Hempstead
  • Patent number: 6234989
    Abstract: An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various aspects of the apheresis procedure. Moreover, the system also includes a variety of features relating to loading a blood processing vessel into a blood processing channel and removing the same after completion of the procedure. Furthermore, the system also includes a variety of features relating to utilizing a blood priming of at least portions of the apheresis system in preparation for the procedure. In addition, the system includes a variety of features enhancing the performance of the apheresis system, including the interrelationship between the blood processing vessel and the blood processing vessel and the utilization of high packing factors for the procedure.
    Type: Grant
    Filed: April 28, 1998
    Date of Patent: May 22, 2001
    Assignee: Gambro, Inc.
    Inventors: Mark J. Brierton, Victor D. Dolecek, Leon E. Bilodeau, Russell Hempstead
  • Patent number: 5921950
    Abstract: An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various aspects of the apheresis procedure. Moreover, the system also includes a variety of features relating to loading a blood processing vessel into a blood processing channel and removing the same after completion of the procedure. Furthermore, the system also includes a variety of features relating to utilizing a blood priming of at least portions of the apheresis system in preparation for the procedure. In addition, the system includes a variety of features enhancing the performance of the apheresis system, including the interrelationship between the blood processing vessel and the blood processing vessel and the utilization of high packing factors for the procedure.
    Type: Grant
    Filed: October 10, 1997
    Date of Patent: July 13, 1999
    Assignee: COBE Laboratories, Inc.
    Inventors: Coy Toavs, John J. Kappus, Mark J. Brierton, David R. Shouldice, Jeffrey J. Blakeslee
  • Patent number: 5919154
    Abstract: An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various aspects of the apheresis procedure. Moreover, the system also includes a variety of features relating to loading a blood processing vessel into a blood processing channel and removing the same after completion of the procedure. Furthermore, the system also includes a variety of features relating to utilizing a blood priming of at least portions of the apheresis system in preparation for the procedure. In addition, the system includes a variety of features enhancing the performance of the apheresis system, including the interrelationship between the blood processing vessel and the blood processing vessel and the utilization of high packing factors for the procedure.
    Type: Grant
    Filed: October 10, 1997
    Date of Patent: July 6, 1999
    Assignee: COBE Laboratories, Inc.
    Inventors: Coy Toavs, John J. Kappus, Mark J. Brierton, David R. Shouldice, Jeffrey J. Blakeslee
  • Patent number: 5795317
    Abstract: An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various aspects of the apheresis procedure. Moreover, the system also includes a variety of features relating to loading a blood processing vessel into a blood processing channel and removing the same after completion of the procedure. Furthermore, the system also includes a variety of features relating to utilizing a blood priming of at least portions of the apheresis system in preparation for the procedure. In addition, the system includes a variety of features enhancing the performance of the apheresis system, including the interrelationship between the blood processing vessel and the blood processing vessel and the utilization of high packing factors for the procedure.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: August 18, 1998
    Assignee: Cobe Laboratories, Inc.
    Inventors: Mark J. Brierton, Victor D. Dolecek, Leon E. Bilodeau, Russell Hempstead
  • Patent number: 5676644
    Abstract: An extracorporeal blood processing system is disclosed which includes a variety of novel components and which may be operated in accordance with a variety of novel methodologies. For instance, the system includes a graphical operator interface which directs the operator through various aspects of the apheresis procedure. Moreover, the system also includes a variety of features relating to loading a blood processing vessel into a blood processing channel and removing the same after completion of the procedure. Furthermore, the system also includes a variety of features relating to utilizing a blood priming of at least portions of the apheresis system in preparation for the procedure. In addition, the system includes a variety of features enhancing the performance of the apheresis system, including the interrelationship between the blood processing vessel and the blood processing vessel and the utilization of high packing factors for the procedure.
    Type: Grant
    Filed: June 7, 1995
    Date of Patent: October 14, 1997
    Assignee: Cobe Laboratories, Inc.
    Inventors: Coy Toavs, John J. Kappus, Mark J. Brierton, David R. Shouldice, Jeffrey J. Blakeslee
  • Patent number: 5356365
    Abstract: A temperature-controlled centrifuge in which a heat exchanger is attached to the bottom portion of the centrifuge bowl to remove heat from the bowl and materials within the bowl interacting therewith. In one embodiment, a heat exchange plate having a plurality of substantially annular channels is appropriately attached to the bottom of the centrifuge bowl and has a surface which is thus substantially coextensive therewith. Each of these channels are positioned at different radial distances from the central axis of the heat exchange plate and each extends substantially about such axis. An appropriate heat transfer medium may thus be circulated through each of these channels to thereby substantially control a temperature across the entire bottom of the bowl. The heat transfer medium may be provided to each of the channels by a common feed inlet which also allows for the use of flow regulators where appropriate, and the heat transfer medium may also thus be removed from the channels by a common dump line.
    Type: Grant
    Filed: February 25, 1994
    Date of Patent: October 18, 1994
    Assignee: Cobe Laboratories, Inc.
    Inventor: Mark J. Brierton