Patents by Inventor Mark J. Murray

Mark J. Murray has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8603777
    Abstract: Methods are disclosed for producing proteins having biological activity for blood coagulation mediated by Factor VIIa or Factor IX. The proteins are produced by mammalian host cells which have been stably transfected with a DNA construct containing a nucleotide sequence which codes at least partially for either Factor VII or Factor IX. The nucleotide sequence comprises a first nucleotide sequence encoding a calcium binding domain, joined to a second nucleotide sequence positioned downstream of the first sequence. The second sequence encodes a catalytic domain for the serine protease activity of either Factor VIIa or Factor IX. The joined sequences code for proteins having substantially the same biological activity for blood coagulation as either Factor VIIa or Factor IX.
    Type: Grant
    Filed: September 25, 1991
    Date of Patent: December 10, 2013
    Assignee: ZymoGenetrics, Inc.
    Inventors: Frederick S. Hagen, Mark J. Murray, Sharon J. Busby, Kathleen L. Berkner, Margaret Y. Insley, Richard G. Woodbury, Charles L. Gray
  • Patent number: 8360160
    Abstract: Methods and apparatus are provided to place a conductor pipe and a casing in a subsea environment. In one embodiment, a conductor pipe is jetted or drilled into the subsea floor. Thereafter, a casing drilling assembly comprising a drill casing and a drilling assembly is connected to the drill pipe using a crossover. The drilling assembly urged into the seafloor until a casing latch on the drilling assembly is engaged with a casing profile of the conductor pipe. During drilling, instrumentation in the drilling assembly may be used to measure geophysical data. The measured data may be used to optimize the drilling process. After the drill casing is engaged with the conductor pipe, cementing may be performed to set the drill casing.
    Type: Grant
    Filed: May 10, 2011
    Date of Patent: January 29, 2013
    Assignee: Weatherford/Lamb, Inc.
    Inventors: Richard L. Giroux, Doug Reid, Albert C. Odell, II, Gregory G. Galloway, Mark J. Murray
  • Publication number: 20120006567
    Abstract: Methods and apparatus are provided to place a conductor pipe and a casing in a subsea environment. In one embodiment, a conductor pipe is jetted or drilled into the subsea floor. Thereafter, a casing drilling assembly comprising a drill casing and a drilling assembly is connected to the drill pipe using a crossover. The drilling assembly urged into the seafloor until a casing latch on the drilling assembly is engaged with a casing profile of the conductor pipe. During drilling, instrumentation in the drilling assembly may be used to measure geophysical data. The measured data may be used to optimize the drilling process. After the drill casing is engaged with the conductor pipe, cementing may be performed to set the drill casing.
    Type: Application
    Filed: May 10, 2011
    Publication date: January 12, 2012
    Inventors: Richard L. Giroux, Doug Reid, Albert C. Odell, II, Gregory G. Galloway, Mark J. Murray
  • Patent number: 7938201
    Abstract: Methods and apparatus are provided to place a conductor pipe and a casing in a subsea environment. In one embodiment, a conductor pipe is jetted or drilled into the subsea floor. Thereafter, a casing drilling assembly comprising a drill casing and a drilling assembly is connected to the drill pipe using a crossover. The drilling assembly urged into the seafloor until a casing latch on the drilling assembly is engaged with a casing profile of the conductor pipe. During drilling, instrumentation in the drilling assembly may be used to measure geophysical data. The measured data may be used to optimize the drilling process. After the drill casing is engaged with the conductor pipe, cementing may be performed to set the drill casing.
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: May 10, 2011
    Assignee: Weatherford/Lamb, Inc.
    Inventors: Richard L. Giroux, Doug Reid, Albert C. Odell, II, Gregory G. Galloway, Mark J. Murray
  • Patent number: 7069991
    Abstract: Apparatus and method for controlling pressure surges in a wellbore. One embodiment provides a downhole surge control tool equipped with a fluid motivator. The fluid motivator may be, for example, any type of motor or a venturi. The fluid motivator motivates wellbore fluid through a bypass channel formed in the tool and then out an exhaust port of the tool.
    Type: Grant
    Filed: January 9, 2003
    Date of Patent: July 4, 2006
    Assignee: Weatherford/Lamb, Inc.
    Inventors: Tarald Gudmestad, Mark J. Murray
  • Patent number: 6908121
    Abstract: A connector arrangement used for connecting and locking tubular members. The connector consists of two tubular members and a coupling member. The tubular members are threaded together to create a threaded connection. The locking arrangement is provided by a pathway formed on the tubular member whereby a locking member can be inserted in to the pathway to lock the threaded connection. The locking arrangement is also provided by a plurality of castellation members disposed on each tubular member. The connector also has a separate coupling member which has opposite right-hand and left-hand threaded ends to threadedly mate with the threads of the two tubular members.
    Type: Grant
    Filed: October 21, 2002
    Date of Patent: June 21, 2005
    Assignee: Weatherford/Lamb, Inc.
    Inventors: David Eugene Hirth, Tarald Gudmestad, Mark J. Murray, Gerald Dean Pedersen
  • Publication number: 20040134664
    Abstract: Apparatus and method for controlling pressure surges in a wellbore. One embodiment provides a downhole surge control tool equipped with a fluid motivator. The fluid motivator may be, for example, any type of motor or a venturi. The fluid motivator motivates wellbore fluid through a bypass channel formed in the tool and then out an exhaust port of the tool.
    Type: Application
    Filed: January 9, 2003
    Publication date: July 15, 2004
    Inventors: Tarald Gudmestad, Mark J. Murray
  • Publication number: 20030122373
    Abstract: The present invention provides a connector arrangement for connecting and locking tubular members. The connector consists of two tubular members and a coupling member. The tubular members are threaded together to create a threaded connection. The locking arrangement is provided by a pathway formed on the tubular member whereby a locking member can be inserted in to the pathway to lock the threaded connection. The locking arrangement is also provided by a plurality of castellation members disposed on each tubular member. The connector also has a separate coupling member which has opposite right-hand and left-hand threaded ends to threadedly mate with the threads of the two tubular members.
    Type: Application
    Filed: October 21, 2002
    Publication date: July 3, 2003
    Inventors: David Eugene Hirth, Tarald Gudmestad, Mark J. Murray, Gerald Dean Pedersen
  • Patent number: 6554062
    Abstract: The well reference apparatus and method of the present invention includes an anchor member with a orientation member preferably permanently installed within the borehole at a preferred depth and orientation in one trip into the well. The orientation member provides a permanent reference for the orientation of well operations, particularly in a multi-lateral well. The assembly of the present invention includes disposing the anchor member and orientation member on the end of a pipe string. An orienting tool such as an MWD collar is disposed in the pipe string above the anchor member. This assembly is lowered into the borehole on the pipe string. Once the preferred depth is attained, the MWD is activated to determine the orientation of the orientation member. If the orientation member is not oriented in the preferred direction, the pipe string is rotated to align the orientation member in the preferred direction.
    Type: Grant
    Filed: May 19, 2000
    Date of Patent: April 29, 2003
    Assignee: Smith International, Inc.
    Inventors: Charles H. Dewey, Mark J. Murray, Wei Xu
  • Patent number: 6009943
    Abstract: The liner assembly and method includes lowering a liner, liner hanger, liner hanger setting tool, liner packer, and liner packer setting tool into the borehole on a work string. The liner hanger is set either hydraulically or mechanically using the liner hanger setting tool at the option of the operator. The liner is then cemented within the borehole and the liner packer setting tool is used to set the liner packer either hydraulically or mechanically at the option of the operator. The liner packer setting tool includes an actuator assembly mounted on the exterior of a tubular body. The actuator assembly includes an actuator member having a contact member which engages the packing element on the liner packer such that upon movement of the contact member with respect to the liner packer, the packing element on the liner packer is compressed to sealingly engage the cased borehole. The actuator member is sealed from the fluid pressure within the borehole until the liner packer is to be set.
    Type: Grant
    Filed: December 22, 1998
    Date of Patent: January 4, 2000
    Assignee: Smith International, Inc.
    Inventors: John M. Yokley, James A. Simson, Mark J. Murray, Robert R. Olman
  • Patent number: 6004929
    Abstract: Dimeric proteins having substantially the same biological activity as PDGF are disclosed. More specifically, the protein may have two substantially identical polypeptide chains, each of the chains being substantially homologous to the A-chain of PDGF. Alternatively, the protein may have two polypeptide chains that are substantially identical to the A-chain of PDGF. In addition, proteins comprising polypeptides that are variants or derivatives of the A-chain of PDGF are also disclosed. Therapeutic compositions containing these proteins and methods for enhancing the wound-healing process in warm-blooded animals are also disclosed.
    Type: Grant
    Filed: March 29, 1995
    Date of Patent: December 21, 1999
    Assignee: ZymoGenetics, Inc.
    Inventors: Mark J. Murray, James D. Kelly
  • Patent number: 5905142
    Abstract: PDGF B-chain polypeptides characterized by the substitution or deletion of a lysine or arginine residue at position 27, 28, 32, 79, 80 or 81 of native B-chain are disclosed. Also disclosed are PDGF-like proteins containing the B-chain polypeptides. The polypeptides and proteins may be produced through the use of cultured cells transfected or transformed to express DNA molecules that encode the polypeptides. The PDGF-like proteins are useful as components of cell culture media and for accelerating the healing of wounds.
    Type: Grant
    Filed: May 8, 1995
    Date of Patent: May 18, 1999
    Assignee: ZymoGenetics, Inc.
    Inventor: Mark J. Murray
  • Patent number: 5895755
    Abstract: PDGF B-chain polypeptides characterized by the substitution or deletion of a lysine or arginine residue at position 27, 28, 32, 79, 80 or 81 of native B-chain are disclosed. Also disclosed are PDGF-like proteins containing the B-chain polypeptides. The polypeptides and proteins may be produced through the use of cultured cells transfected or transformed to express DNA molecules that encode the polypeptides. The PDGF-like proteins are useful as components of cell culture media and for accelerating the healing of wounds.
    Type: Grant
    Filed: September 9, 1994
    Date of Patent: April 20, 1999
    Assignee: ZymoGenetics, Inc.
    Inventor: Mark J. Murray
  • Patent number: 5887660
    Abstract: The liner packer assembly and method includes a liner packer having a tubular body with an aperture for the flow of wellbore fluids. A packing element is movably disposed on the tubular body between an open position on one side of the aperture for allowing wellbore fluids to flow through the aperture to a closed position on the other side of the aperture for closing flow through the aperture and for packing off the annulus between the packer and outer casing. During the cementing operation, drilling fluids and cement are allowed to flow through the annular area formed by the packer and outer casing and also flow through the aperture in the tubular body of the packer and up the inside diameter or inner annular area formed by the packer and inner tubular string. The inner and outer annular areas around packer approximately the flow area below the packer between the inner tubular string and the outer casing.
    Type: Grant
    Filed: January 14, 1997
    Date of Patent: March 30, 1999
    Assignee: Smith International, Inc
    Inventors: John M. Yokley, Mark J. Murray, Ronald J. Selby, Robert Richard Olman
  • Patent number: 5884702
    Abstract: The liner assembly and method includes lowering a liner, liner hanger, liner hanger setting tool, liner packer, and liner packer setting tool into the borehole on a work string. The liner hanger is set either hydraulically or mechanically using the liner hanger setting tool at the option of the operator. The liner is then cemented within the borehole and the liner packer setting tool is used to set the liner packer either hydraulically or mechanically at the option of the operator. The liner packer setting tool includes an actuator assembly mounted on the exterior of a tubular body. The actuator assembly includes an actuator member having a contact member which engages the packing element on the liner packer such that upon movement of the contact member with respect to the liner packer, the packing element on the liner packer is compressed to sealingly engage the cased borehole. The actuator member is sealed from the fluid pressure within the borehole until the liner packer is to be set.
    Type: Grant
    Filed: January 14, 1997
    Date of Patent: March 23, 1999
    Assignee: Smith International, Inc.
    Inventors: John M. Yokley, James A. Simson, Mark J. Murray, Robert R. Olman
  • Patent number: 5785133
    Abstract: An assembly for drilling multiple laterals (26) from a borehole and into a formation includes a whipstock assembly having a radially movable lug (82). An elongate tubular secured within the borehole has one or more non-ferrous portions (30) and a ferrous portion (52) adjacent and below a respective non-ferrous portion. A locator (54) is fixed within each ferrous portion at a desired axial spacing relative to the non-ferrous portion. According to the method of the invention, the whipstock assembly is lowered below the locator (54) and pulled upwardly to rotate the whipstock assembly to a selected azimuth within the tubular. The lug (82) on the whipstock assembly fits within the locator to axially position the whipstock face (97) within the non-ferrous portion of the tubular. A drill bit (96) engages the whipstock face and drills a window through the non-ferrous portion of the tubular and then into the formation.
    Type: Grant
    Filed: August 29, 1995
    Date of Patent: July 28, 1998
    Assignee: TIW Corporation
    Inventors: Mark J. Murray, Britt O. Braddick
  • Patent number: 5618678
    Abstract: Isolated DNA molecules that encode a novel PDGF receptor are disclosed. The receptor binds the AA, AB and BB isoforms of PDGF with high affinity. Cells transfected or transformed with the DNA molecules are also disclosed. The cells can be used within methods for detecting PDGF agonist or antagonist activity in a test compound.
    Type: Grant
    Filed: November 16, 1994
    Date of Patent: April 8, 1997
    Assignee: ZymoGenetics, Inc.
    Inventors: James D. Kelly, Mark J. Murray
  • Patent number: 5516650
    Abstract: Methods are disclosed for producing a protein which has substantially the same biological activity as human protein C or human activated protein C. The protein is produced by mammalian host cells transfected with a plasmid capable of integration in mammalian host cell DNA. The plasmid includes a promoter followed downstream by a nucleotide sequence which encodes a protein having substantially the same structure and/or activity as human protein C or human activated protein C the nucleotide sequence being followed downstream by a polyadenylation signal.
    Type: Grant
    Filed: April 8, 1994
    Date of Patent: May 14, 1996
    Assignee: Zymogenetics, Inc.
    Inventors: Donald C. Foster, Mark J. Murray, Kathleen L. Berkner
  • Patent number: 5516896
    Abstract: Dimeric proteins having substantially the same biological activity as PDGF are disclosed. More specifically, the protein may have two substantially identical polypeptide chains, each of the chains being substantially homologous to the B-chain of PDGF. Alternatively, the protein may have two polypeptide chains that are substantially identical to the B-chain of PDGF. In addition, proteins comprising polypeptides that are variants or derivatives of the B-chain of PDGF are also disclosed. Therapeutic compositions containing these proteins and methods for enhancing the wound-healing process in warm-blooded animals are also disclosed.
    Type: Grant
    Filed: July 13, 1989
    Date of Patent: May 14, 1996
    Assignee: ZymoGenetics, Inc.
    Inventors: Mark J. Murray, James D. Kelly
  • Patent number: 5498600
    Abstract: Dimeric proteins having substantially the same biological activity as PDGF are disclosed. More specifically, the proteins may have two polypeptide chains, one of the chains being a mosaic of amino acid sequences substantially identical to portions of the A- or B-chains of PDGF, the second of the chains being substantially homologous to either the A-chain or the B-chain of PDGF, the proteins being chemotactic or mitogenic for fibroblasts. Alternatively, each of the two polypeptide chains may be a mosaic of amino acid sequences as described above. Therapeutic compositions containing these proteins and methods for enhancing the wound-healing process in warm-blooded animals are also disclosed.
    Type: Grant
    Filed: October 7, 1994
    Date of Patent: March 12, 1996
    Assignee: ZymoGenetics, Inc.
    Inventors: Mark J. Murray, James D. Kelly