Patents by Inventor Mark J. Rupar

Mark J. Rupar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Bacillus thuringiensis CryET29 compositions toxic to coleopteran insects and Ctenocephalides SPP
    Patent number: 6537756
    Abstract: Disclosed is a novel &dgr;-endotoxin, designated CryET29, that exhibits insecticidal activity against siphonapteran insects, including larvae of the cat flea (Ctenocephalides felis), as well as against coleopteran insects, including the southern corn rootworm (Diabrotica undecimpunctata), western corn rootworm (D. virgifera), Colorado potato beetle (Leptinotarsa decemlineata), Japanese beetle (Popillia japonica), and red flour beetle (Tribolium castaneum). Also disclosed are nucleic acid segments encoding CryET29, recombinant vectors, host cells, and transgenic plants comprising a cryET29 DNA segment. Methods for making and using the disclosed protein and nucleic acid segments are disclosed as well as assays and diagnostic kits for detecting cryET29 and CryET29 sequences in vivo and in vitro.
    Type: Grant
    Filed: July 6, 2000
    Date of Patent: March 25, 2003
    Assignee: Monsanto Technology, LLC
    Inventors: Mark J. Rupar, William P. Donovan, Yuping Tan, Annette C. Slaney
  • Bacillus thuringiensis CryET29 compositions toxic to coleopteran insects and ctenocephalides SPP
    Patent number: 6093695
    Abstract: Disclosed is a novel .delta.-endotoxin, designated CryET29, that exhibits insecticidal activity against siphonapteran insects, including larvae of the cat flea (Ctenocephalides felis), as well as against colcopteran insects, including the southern corn rootworm (Diabrotica undecimpunctata), western corn rootworm (D. virgifera), Colorado potato beetle (Leptinotarsa decemlineata), Japanese beetle (Popillia japonica), and red flour beetle (Tribolium castaneur). Also disclosed are nucleic acid segments encoding CryET29, recombinant vectors, host cells, and transgenic plants comprising a cryET29 DNA segment. Methods for making and using the disclosed protein and nucleic acid segments are disclosed as well as assays and diagnostic kits for detecting cryET29 and CryET29 sequences in vivo and in vitro.
    Type: Grant
    Filed: September 26, 1996
    Date of Patent: July 25, 2000
    Assignee: Monsanto Company
    Inventors: Mark J. Rupar, William P. Donovan, Yuping Tan, Annette C. Slaney
  • Bacillus thuringiensis protein toxic to coleopteran insects
    Patent number: 5382429
    Abstract: A purified and isolated cryIII-type gene was obtained from a novel B.t. strain. The gene has a nucleotide base sequence coding for the amino acid sequence illustrated in FIG. 1 . The 74.4 kDa protein produced by this gene is an irregularly shaped crystal that is toxic to coleopteran insects, including Colorado potato beetle and insects of the genus Diabrotica.
    Type: Grant
    Filed: September 24, 1992
    Date of Patent: January 17, 1995
    Assignee: Ecogen Inc.
    Inventors: William P. Donovan, Mark J. Rupar, Annette C. Slaney, Timothy B. Johnson
  • Bacillus thuringiensis cryIIIC, (b) protein toxic to coleopteran insects
    Patent number: 5378625
    Abstract: A Bacillus thuringiensis strain isolate, designated EG5144, exhibits insecticidal activity against coleopteran insects, including Colorado potato beetle and insects of the genus Diabrotica. A novel toxin gene in B.t. strain EG5144 produces an irregularly shaped insecticidal crystal protein of approximately 70 kDa that is toxic to coleopteran insects. The cryIII-type gene (SEQ ID NO:1), designated as the cryIIIC(b) gene, has a nucleotide base sequence illustrated in FIG. 1.
    Type: Grant
    Filed: August 27, 1993
    Date of Patent: January 3, 1995
    Assignee: Ecogen, Inc.
    Inventors: William P. Donovan, Mark J. Rupar, Annette C. Slaney
  • Bacillus thuringiensis cryIIIc(B) toxin gene and protein toxic to coleopteran insects
    Patent number: 5264364
    Abstract: A Bacillus thuringiensis strain isolate, designated EG5144, exhibits insecticidal activity against coleopteran insects, including Colorado potato beetle and insects of the genus Diabrotica. A novel toxin gene in B.t. strain EG5144 produces an irregularly shaped insecticidal crystal protein of approximately 70 kDa that is toxic to coleopteran insects. The cryIII-type gene (SEQ ID NO:1), designated as the cryIIIC(b) gene, has a nucleotide base sequence illustrated in FIG. 1.
    Type: Grant
    Filed: March 15, 1993
    Date of Patent: November 23, 1993
    Assignee: Ecogen Inc.
    Inventors: Willam P. Donovan, Mark J. Rupar, Annette C. Slaney
  • Bacillus thuringiensis cryIIIC gene encoding toxic to coleopteran insects
    Patent number: 5187091
    Abstract: A purified and isolated cryIII-type gene was obtained from a novel B.t. strain. The gene has a nucleotide base sequence coding for the amino acid sequence illustrated in FIG. 1. The 74.4 kDa protein produced by this gene is an irregularly shaped crystal that is toxic to coleopteran insects, including Colorado potato beetle and insects of the genus Diabrotica.
    Type: Grant
    Filed: March 20, 1990
    Date of Patent: February 16, 1993
    Assignee: Ecogen Inc.
    Inventors: William P. Donovan, Mark J. Rupar, Annette C. Slaney, Timothy B. Johnson