Patents by Inventor Mark J. Smyth

Mark J. Smyth has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHOD OF TREATMENT
    Publication number: 20220213198
    Abstract: The present disclosure relates to methods for the treatment of cancer, methods of increasing the response of tumor cells in a subject to cancer therapy, as well as methods of predicting a positive clinical response to a cancer therapy in a patient.
    Type: Application
    Filed: May 22, 2020
    Publication date: July 7, 2022
    Inventors: Michele WL TENG, Juming YAN, Mark J SMYTH
  • Serine protease and uses thereof
    Patent number: 5500344
    Abstract: The present invention provides a purified and isolated nucleic acid molecule encoding serine protease (Met-ase) having Met-ase activity but not Asp-ase activity and a molecular weight of about 30,000 daltons on SDS PAGE under reducing and non-reducing conditions. The present invention also provides a vector comprising this nucleic acid molecule, a prokaryotic or eukaryotic host cell stably transformed or transfected with the vector, as well as a method for detecting this nucleic acid in a sample.
    Type: Grant
    Filed: December 3, 1992
    Date of Patent: March 19, 1996
    Assignee: The United States of America as represented by the Department of Health and Human Services
    Inventors: Thomas Sayers, Mark J. Smyth, Theresa A. Wiltrout, James C. Powers, Raymond Sowder, Louis E. Henderson