Patents by Inventor Mark James Davis
Mark James Davis has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 8361386Abstract: An enzyme detection product (1) for detecting the presence of an enzyme in a sample. The product (1) comprises: a reaction zone (16) for receiving the sample; a visualization zone (10) for presenting a signal in response to the detection of the activity of the enzyme; and a membrane (11). The membrane (11) is interposable between the reaction zone (16) and the visualization zone (10) and prevents passage from the reaction zone (16) to the visualization zone (10) the components having a size greater than a threshold size. The reaction zone (16) comprises a reactant capable of reacting with the enzyme in order to generate a reaction product having a size less than a threshold size.Type: GrantFiled: February 23, 2007Date of Patent: January 29, 2013Assignee: Mologic LTDInventors: Paul James Davis, Mark James Davis, Mark Burnapp, Sandra Hemmington
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Patent number: 8241588Abstract: A binding assay product (1) for detecting the presence of an analyte in a sample comprising a labelling module (5), a label, a capture module (9) and a visualization module (10). The labelling module (5) comprises a first binding component capable of binding the analyte. The label is connectable to the first binding component. The capture module (9) comprises a second binding component capable of binding the analyte. The visualization module (10) is for detecting the first binding component connected to the label and bound to the second binding component via the analyte. The labelling module and the capture module comprise a fluid conducting medium in which the binding components are embedded. The labelling module (5), the capture module (9) and the visualization module (10) together define a flow path along which the sample is capable of flowing.Type: GrantFiled: February 23, 2007Date of Patent: August 14, 2012Assignee: Mologic LtdInventors: Paul James Davis, Mark James Davis, Mark Burnapp, Julie Thompson
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Patent number: 7935497Abstract: A method of detecting a protease in a sample. The method comprises providing an analyte degradable by the protease. The analyte is contacted with the sample. The degradation products of the analyte or the residual undegraded analyte is detected in a binding assay.Type: GrantFiled: February 23, 2007Date of Patent: May 3, 2011Assignee: Mologic LtdInventors: Paul James Davis, Mark James Davis, Mark Burnapp
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Publication number: 20090203059Abstract: A protease detection product (1) for detecting a protease enzyme in a sample. The protease detection product (1) comprises a medium (2) providing a liquid flow path; a labelled component (6) located on the liquid flow path; a capture component (12) located downstream of the labelled component (6) and immobilisation means (8) for immobilising the intact labelled component. The labelled component (7) comprises a base element (8) connected to releasable element via a protease-sensitive linker peptide (9). The releasable element comprises a label (10). The capture component (12) is capable of binding the releasable element.Type: ApplicationFiled: April 5, 2007Publication date: August 13, 2009Applicant: Mologic Ltd.Inventors: Mark James Davis, Paul James Davis, Mark Burnapp
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Publication number: 20090191582Abstract: An enzyme detection product (1) for detecting the presence of an enzyme in a sample. The product (1) comprises: a reaction zone (16) for receiving the sample; a visualization zone (10) for presenting a signal in response to the detection of the activity of the enzyme; and a membrane (11). The membrane (11) is interposable between the reaction zone (16) and the visualization zone (10) and prevents passage from the reaction zone (16) to the visualization zone (10) the components having a size greater than a threshold size. The reaction zone (16) comprises a reactant capable of reacting with the enzyme in order to generate a reaction product having a size less than a threshold size.Type: ApplicationFiled: February 23, 2007Publication date: July 30, 2009Applicant: Mologic LtdInventors: Paul James Davis, Mark James Davis, Mark Burnapp, Sandra Hemmington
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Publication number: 20090098020Abstract: A binding assay product (1) for detecting the presence of an analyte in a sample comprising a labelling module (5), a label, a capture module (9) and a visualisation module (10). The labelling module (5) comprises a first binding component capable of binding the analyte. The label is connectable to the first binding component. The capture module (9) comprises a second binding component capable of binding the analyte. The visualisation module (10) is for detecting the first binding component connected to the label and bound to the second binding component via the analyte. The labelling module and the capture module comprise a fluid conducting medium in which the binding components are embedded. The labelling module (5), the capture module (9) and the visualisation module (10) together define a flow path along which the sample is capable of flowing.Type: ApplicationFiled: February 23, 2007Publication date: April 16, 2009Applicant: Mologic LtdInventors: Paul James Davis, Mark James Davis, Mark Burnapp, Julie Thompson
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Publication number: 20090053738Abstract: A method of detecting a protease in a sample. The method comprises providing an analyte degradable by the protease. The analyte is contacted with the sample. The degradation products of the analyte or the residual undegraded analyte is detected in a binding assay.Type: ApplicationFiled: February 23, 2007Publication date: February 26, 2009Applicant: Mologic Ltd.Inventors: Paul James Davis, Mark James Davis, Mark Burnapp