Patents by Inventor Mark Jeffrey Edhouse
Mark Jeffrey Edhouse has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20200054558Abstract: An aerosol preparation assembly includes an entrainment chamber defining an entrainment volume. The entrainment chamber includes a gas inlet port, an aerosol inlet port and an outlet port. The entrainment chamber is configured such that a velocity of a flow of a gas within the entrainment volume is less than a velocity of the flow of the gas within the gas inlet port. The entrainment chamber is configured such that at least a portion of inlet aerosol is entrained into the flow of the gas within the entrainment volume to produce an entrained aerosol flow at the outlet port. The particle selection chamber is configured to receive the entrained aerosol flow and produce an outlet aerosol flow. The particle selection chamber and nozzle are collectively configured such that a volumetric median diameter of the outlet aerosol flow is less than a volumetric median diameter of the inlet aerosol.Type: ApplicationFiled: March 20, 2019Publication date: February 20, 2020Applicant: PARION SCIENCES, INC.Inventors: Paul BOUCHER, Richard BOUCHER, Brian M. BUTTON, Michael R. JOHNSON, James B. FINK, Anthony J. HICKEY, Tomas NAVRATIL, William Robert THELIN, Stuart Robert ABERCROMBIE, Philip Jerome DRIVER, Mark Jeffrey EDHOUSE, Nicholas O. HEIJNE, Donal Joseph TAYLOR, Jonathan Hugh WILKINS
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Patent number: 9555189Abstract: A fluid management system adapted to automatically supply fluid for injection into a patient is disclosed. The fluid management system includes a fluid management device, a fluid transfer system and a fluid injector. The fluid management device serves to store and administrate multi-dose containers. The fluid transfer system connects an outlet of these containers to the injector which withdraws a fluid from the containers via the fluid transfer system and injects the fluid to an administration device at the patient. The fluid management device includes at least one rotating carousel having a vertical axis of rotation, at least two container holders attached to the rotating carousel and adapted to position the container vertically with a septum covered end facing downwards, and a spike holder mounted below the rotating carousel and oriented so the spike holder axially aligns a spike connected to the spike holder with the axis of the container.Type: GrantFiled: November 24, 2010Date of Patent: January 31, 2017Assignee: BAYER INTELLECTUAL PROPERTY GMBHInventors: Claus-Peter Reisinger, Klaus Urich, Matthias Burg, Andreas Kalitzki, Samantha Anne Patterson, Kathryn Anne Louise Farrell, Andrew Murray Gow, Scott Alexander Lewis, Mark Jeffrey Edhouse
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Publication number: 20150150803Abstract: An aerosol preparation assembly includes an entrainment chamber defining an entrainment volume. The entrainment chamber includes a gas inlet port, an aerosol inlet port and an outlet port. The entrainment chamber is configured such that a velocity of a flow of a gas within the entrainment volume is less than a velocity of the flow of the gas within the gas inlet port. The entrainment chamber is configured such that at least a portion of inlet aerosol is entrained into the flow of the gas within the entrainment volume to produce an entrained aerosol flow at the outlet port. The particle selection chamber is configured to receive the entrained aerosol flow and produce an outlet aerosol flow. The particle selection chamber and nozzle are collectively configured such that a volumetric median diameter of the outlet aerosol flow is less than a volumetric median diameter of the inlet aerosol.Type: ApplicationFiled: January 9, 2015Publication date: June 4, 2015Applicant: PARION SCIENCES, INC.Inventors: Paul BOUCHER, Richard BOUCHER, Brian M. BUTTON, Michael R. JOHNSON, James B. FINK, Anthony J. HICKEY, Tomas NAVRATIL, William Robert THELIN, Stuart Robert ABERCROMBIE, Philip Jerome DRIVER, Mark Jeffrey EDHOUSE, Nicholas O. HEIJNE, Donal Joseph TAYLOR, Jonathan Hugh WILKINS
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Patent number: 9017293Abstract: A device for the automatic injection of doses of a drug compound is described. The device has a sliding sheath which, when depressed with its front end against the injection site, interacts with cam means to activate triggering of a plunger, thus controlling delivery of a drug dose. Plunger guide means are provided for controlling the triggering sequence and means for arming the device in the dose delivery condition. Automatic needle re-sheathing and resetting of a lock-out condition after each dose is delivered are also provided.Type: GrantFiled: September 6, 2012Date of Patent: April 28, 2015Assignee: Menarini International Operations Luxembourg S.A.Inventors: Mark Jeffrey Edhouse, Philip Jerome Driver, Guy Conwyn Julian Moseley, Scott Alexander Lewis
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Patent number: 8961463Abstract: A two-dose autoinjector for a medicament wherein the locking and releasing of the drive spring of the autoinjector is controlled through stepped guides with ramps for two successive slidings of slides operated by the spring and connected with the syringe and plunger. The guides and the slides are pivotable relative to one another and the sliding direction, while the syringe can only slide axially. To enable or disable the sliding of the slides within the guides an angularly angularly mobile arming member is provided formed with a guide track substantially equal to that of the stationary member where the guides are formed.Type: GrantFiled: March 9, 2011Date of Patent: February 24, 2015Assignee: Menarini International Operations Luxembourg S.A.Inventors: Mark Jeffrey Edhouse, Patrick J. Ryan, Max William Middleton, Christopher Edward Butcher
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Patent number: 8945605Abstract: An aerosol preparation assembly includes an entrainment chamber defining an entrainment volume. The entrainment chamber includes a gas inlet port, an aerosol inlet port and an outlet port. The entrainment chamber is configured such that a velocity of a flow of a gas within the entrainment volume is less than a velocity of the flow of the gas within the gas inlet port. The entrainment chamber is configured such that at least a portion of inlet aerosol is entrained into the flow of the gas within the entrainment volume to produce an entrained aerosol flow at the outlet port. The particle selection chamber is configured to receive the entrained aerosol flow and produce an outlet aerosol flow. The particle selection chamber and nozzle are collectively configured such that a volumetric median diameter of the outlet aerosol flow is less than a volumetric median diameter of the inlet aerosol.Type: GrantFiled: March 14, 2013Date of Patent: February 3, 2015Assignee: Parion Sciences, Inc.Inventors: Paul Boucher, Richard Boucher, Brian M. Button, Michael R. Johnson, James B. Fink, Anthony J. Hickey, Tomas Navratil, William Robert Thelin, Stuart Robert Abercrombie, Philip Jerome Driver, Mark Jeffrey Edhouse, Nicholas O. Heijne, Donal Joseph Taylor, Jonathan Hugh Wilkins
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Patent number: 8900201Abstract: A device for the automatic injection of doses of a drug is described. The device has a slide and cam means, a syringe unit with a piston, and guide means. The axial movement of the slide initiated by a user by depressing its front end against an injection site, causes an angular displacement of the cam means that, in cooperation with the guide means, controls movement of the syringe piston and therefore administration of a drug dose.Type: GrantFiled: September 6, 2012Date of Patent: December 2, 2014Assignee: Menarini International Operations Luxembourg S.A.Inventors: Mark Jeffrey Edhouse, Philip Jerome Driver, Guy Conwyn Julian Moseley, Scott Alexander Lewis
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Patent number: 8870808Abstract: A pyloric valve is provided for inhibiting the flow of chyme through the pyloric region of the gastrointestinal tract. The pyloric valve includes a blocking portion having at least one axially-aligned annular flange defining a central opening and a support having a rim and a support surface. The support may be disposed in a nested position wherein the support surface is disposed within the central opening and an inverted position wherein the support surface is disposed away from the central opening. The pyloric valve may further include a sleeve that may have a beveled distal end. The pyloric valve may be constructed of silicon. Also provided are methods of inserting and removing the pyloric valve, which each include a step of manipulating the support between its inverted and nested positions. Insertion and removal systems are also provided for use with the pyloric valve.Type: GrantFiled: December 23, 2011Date of Patent: October 28, 2014Assignee: E2, LLCInventors: Buket Grau, David Robert Gale, Sam Anne Musgrave, George McGee Perkins, Mark Jeffrey Edhouse, Marc Graham, Christopher Kadamus
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Publication number: 20140257194Abstract: A device for the automatic injection of doses of a drug compound is described. The device has a sliding sheath which, when depressed with its front end against the injection site, interacts with cam means to activate triggering of a plunger, thus controlling delivery of a drug dose. Plunger guide means are provided for controlling the triggering sequence and means for arming the device in the dose delivery condition. Automatic needle re-sheathing and resetting of a lock-out condition after each dose is delivered are also provided.Type: ApplicationFiled: September 6, 2012Publication date: September 11, 2014Applicant: Menarini International Operation Luxembourg S.A.Inventors: Mark Jeffrey EDHOUSE, Philip Jerome DRIVER, Guy Conwyn Julian MOSELEY, Scott Alexander LEWIS
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Publication number: 20140221936Abstract: A device for the automatic injection of doses of a drug is described. The device has a slide and cam means, a syringe unit with a piston, and guide means. The axial movement of the slide initiated by a user by depressing its front end against an injection site, causes an angular displacement of the cam means that, in cooperation with the guide means, controls movement of the syringe piston and therefore administration of a drug dose.Type: ApplicationFiled: September 6, 2012Publication date: August 7, 2014Inventors: Mark Jeffrey Edhouse, Philip Jerome Driver, Guy Conwyn Julian Moseley, Scott Alexander Lewis
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Publication number: 20140158127Abstract: An apparatus can include a nasal cannula assembly, which includes a face piece. The face piece includes a plenum portion and a nasal interface portion. The plenum portion is configured to be coupled to a supply line and defines a flow path configured to receive an aerosol flow from the supply line. The nasal interface portion includes a first delivery protrusion and a second delivery protrusion. The first delivery protrusion is configured to convey a first portion of the aerosol flow to a first nostril, and the second delivery protrusion is configured to deliver a second portion of the aerosol flow to a second nostril. The plenum portion includes a sidewall having a curved surface configured to redirect the second portion of the aerosol flow towards the second delivery protrusion. The sidewall is configured to isolate the flow path from a volume downstream from the second delivery protrusion.Type: ApplicationFiled: December 6, 2013Publication date: June 12, 2014Applicant: PARION SCIENCES, INC.Inventors: Paul BOUCHER, Brian M. BUTTON, James B. FINK, Anthony J. HICKEY, Tomas NAVRATIL, Stuart Robert ABERCROMBIE, Michael Richard BURCHER, Mark Jeffrey EDHOUSE, Jamie Alan GREENWOOD, Emma Jane HASLER, Guy Conwyn Julian MOSELEY, David William SMITH, Donal Joseph TAYLOR, Jonathan Hugh WILKINS
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Patent number: 8579849Abstract: A pyloric valve is provided for inhibiting the flow of chyme through the pyloric region of the gastrointestinal tract. The pyloric valve includes a blocking portion having a disc-shaped inlet and a helical flange. The helical flange may be disposed in a contracted position defining a contracted length and a contracted diameter and an extended position defining an extended length and an extended diameter, wherein the extended length is longer than the contracted length and the extended diameter is smaller than the contracted diameter. The pyloric valve may further include a sleeve that may have a beveled distal end. The pyloric valve may be constructed of silicon. Also provided are methods of inserting and removing the pyloric valve, which each include a step of manipulating the support between its contracted and extended positions. Insertion and removal systems are also provided for use with the pyloric valve.Type: GrantFiled: February 1, 2012Date of Patent: November 12, 2013Assignee: E2 LLCInventors: Buket Grau, David Robert Gale, Sam Anne Musgrave, George McGee Perkins, Mark Jeffrey Edhouse, Marc Graham, Christopher Kadamus
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Publication number: 20130046238Abstract: A two-dose autoinjector for a medicament wherein the locking and releasing of the drive spring of the autoinjector is controlled through stepped guides with ramps for two successive slidings of slides operated by the spring and connected with the syringe and plunger. The guides and the slides are pivotable relative to one another and the sliding direction, while the syringe can only slide axially To enable or disable the sliding of the slides within the guides an angularly angularly mobile arming member is provided formed with a guide track substantially equal to that of the stationary member where the guides are formed.Type: ApplicationFiled: March 9, 2011Publication date: February 21, 2013Applicant: MENARINI INTERNATIONAL OPERATIONS LUXEMBOURG S.A.Inventors: Mark Jeffrey Edhouse, Patrick J. Ryan, Max William Middleton, Christopher Edward Butcher
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Publication number: 20130006381Abstract: A pyloric valve is provided for inhibiting the flow of chyme through the pyloric region of the gastrointestinal tract. The pyloric valve includes a blocking portion having at least one axially-aligned annular flange defining a central opening and a support having a rim and a support surface. The support may be disposed in a nested position wherein the support surface is disposed within the central opening and an inverted position wherein the support surface is disposed away from the central opening. The pyloric valve may further include a sleeve that may have a beveled distal end. The pyloric valve may be constructed of silicon. Also provided are methods of inserting and removing the pyloric valve, which each include a step of manipulating the support between its inverted and nested positions. Insertion and removal systems are also provided for use with the pyloric valve.Type: ApplicationFiled: December 23, 2011Publication date: January 3, 2013Applicant: E2 LLCInventors: Buket Grau, David Robert Gale, Sam Anne Musgrave, George McGee Perkins, Mark Jeffrey Edhouse, Marc Graham, Christopher Kadamus
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Publication number: 20120330152Abstract: The fluid management system according to the invention is adapted to automatically supply fluid for injection into a patient. The fluid management system comprises a fluid management device, a fluid transfer system and a fluid injector. The fluid management device serves to store and administrate multi dose containers. The fluid transfer system connects the outlet of the containers stored within the fluid management device to the injector and the injector withdraws the fluid via fluid transfer system from the containers and injects the fluid to an administration device at the patient.Type: ApplicationFiled: November 24, 2009Publication date: December 27, 2012Inventors: Claus-Peter Reisinger, Klaus Urich, Matthias Burg, Andreas Kalitzki, Samantha Anne Patterson, Kathryn Anne Louise Farrell, Andrew Murray Gow, Scott Alexander Lewis, Mark Jeffrey Edhouse
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Publication number: 20120136457Abstract: A pyloric valve is provided for inhibiting the flow of chyme through the pyloric region of the gastrointestinal tract. The pyloric valve includes a blocking portion having a disc-shaped inlet and a helical flange. The helical flange may be disposed in a contracted position defining a contracted length and a contracted diameter and an extended position defining an extended length and an extended diameter, wherein the extended length is longer than the contracted length and the extended diameter is smaller than the contracted diameter. The pyloric valve may further include a sleeve that may have a beveled distal end. The pyloric valve may be constructed of silicon. Also provided are methods of inserting and removing the pyloric valve, which each include a step of manipulating the support between its contracted and extended positions. Insertion and removal systems are also provided for use with the pyloric valve.Type: ApplicationFiled: February 1, 2012Publication date: May 31, 2012Applicant: E2 LLCInventors: Buket Grau, David Robert Gale, Sam Anne Musgrave, George McGee Perkins, Mark Jeffrey Edhouse, Marc Graham, Christopher Kadamus
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Patent number: 8182442Abstract: A pyloric valve is provided for inhibiting the flow of chyme through the pyloric region of the gastrointestinal tract. The pyloric valve includes a blocking portion having a plurality of disc-shaped flanges connected in series. The blocking portion may be disposed in a contracted position wherein the plurality of disc-shaped flanges is disposed in a stacked configuration and a resting position wherein the plurality of disc-shaped flanges is disposed in a linear configuration. The pyloric valve may further include a sleeve that may have a beveled distal end. The pyloric valve may be constructed of silicon. Also provided are methods of inserting and removing the pyloric valve, which each include a step of manipulating the support between its resting and contracted positions. Insertion and removal systems are also provided for use with the pyloric valve.Type: GrantFiled: April 9, 2009Date of Patent: May 22, 2012Assignee: ElectroCore LLCInventors: Buket Grau, David Robert Gale, Sam Anne Musgrave, George McGee Perkins, Mark Jeffrey Edhouse, Marc Graham, Christopher Kadamus
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Patent number: 8142385Abstract: A pyloric valve is provided for inhibiting the flow of chyme through the pyloric region of the gastrointestinal tract. The pyloric valve includes a blocking portion having a disc-shaped inlet and a helical flange. The helical flange may be disposed in a contracted position defining a contracted length and a contracted diameter and an extended position defining an extended length and an extended diameter, wherein the extended length is longer than the contracted length and the extended diameter is smaller than the contracted diameter. The pyloric valve may further include a sleeve that may have a beveled distal end. The pyloric valve may be constructed of silicon. Also provided are methods of inserting and removing the pyloric valve, which each include a step of manipulating the support between its contracted and extended positions. Insertion and removal systems are also provided for use with the pyloric valve.Type: GrantFiled: April 9, 2009Date of Patent: March 27, 2012Assignee: E2 LLCInventors: Buket Grau, David Robert Gale, Sam Anne Musgrave, George McGee Perkins, Mark Jeffrey Edhouse, Marc Graham, Christopher Kadamus
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Patent number: 8100850Abstract: A pyloric valve is provided for inhibiting the flow of chyme through the pyloric region of the gastrointestinal tract. The pyloric valve includes a blocking portion having at least one axially-aligned annular flange defining a central opening and a support having a rim and a support surface. The support may be disposed in a nested position wherein the support surface is disposed within the central opening and an inverted position wherein the support surface is disposed away from the central opening. The pyloric valve may further include a sleeve that may have a beveled distal end. The pyloric valve may be constructed of silicon. Also provided are methods of inserting and removing the pyloric valve, which each include a step of manipulating the support between its inverted and nested positions. Insertion and removal systems are also provided for use with the pyloric valve.Type: GrantFiled: April 9, 2009Date of Patent: January 24, 2012Assignee: E2 LLCInventors: Buket Grau, David Robert Gale, Sam Anne Musgrave, George McGee Perkins, Mark Jeffrey Edhouse, Marc Graham, Christopher Kadamus
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Publication number: 20090259239Abstract: A pyloric valve is provided for inhibiting the flow of chyme through the pyloric region of the gastrointestinal tract. The pyloric valve includes a blocking portion having at least one axially-aligned annular flange defining a central opening and a support having a rim and a support surface. The support may be disposed in a nested position wherein the support surface is disposed within the central opening and an inverted position wherein the support surface is disposed away from the central opening. The pyloric valve may further include a sleeve that may have a beveled distal end. The pyloric valve may be constructed of silicon. Also provided are methods of inserting and removing the pyloric valve, which each include a step of manipulating the support between its inverted and nested positions. Insertion and removal systems are also provided for use with the pyloric valve.Type: ApplicationFiled: April 9, 2009Publication date: October 15, 2009Applicant: Stryker Development LLCInventors: Buket Grau, David Robert Gale, Sam Anne Musgrave, George McGee Perkins, Mark Jeffrey Edhouse, Marc Graham, Christopher Kadamus