Abstract: Systems and methods of determining whether to initiate a pull of an accumulated data transfer amount are described. An accumulated data transfer amount for a periodic data transfer scheduled to be pushed at a future date is determined. A determination is made of whether an overall data amount in a storage location is expected to be greater at a date on or after the scheduled future date if a pull of the accumulated data transfer amount is performed before the scheduled future date than if a pull operation is not performed and the accumulated data transfer amount is sent at the scheduled future date. When the overall data amount in the storage location is expected to be greater at the scheduled future date if the pull of the accumulated data transfer amount is performed, a pull of the accumulated data transfer amount is initiated.

Abstract: Provided herein are gRNA comprising a targeting domain that targets CD30, which may be used, for example, to make modifications in cells. Also provided herein are methods of genetically engineered cell having a modification (e.g., insertion or deletion) in the CD30 gene and methods involving administering such genetically engineered cells to a subject, such as a subject having a hematopoietic malignancy.

Abstract: In an aspect, the present application describes a computer system. The computer system includes a communications module and a processor coupled to the communications module. The computer system include a memory coupled to the processor storing instructions that, when executed by the computer system, cause the computer system to: receive, from an automated teller machine (ATM) and via the communications module, an indication of a deposit of a value instrument; save, in the memory, a retention instruction including an associated temporal period, the retention instruction preventing withdrawal of value instruments corresponding to an amount of the deposit; receive, via the communications module, an instruction to process a data transfer to a recipient, the data transfer to the recipient accessing at least a portion of the deposit; and process the data transfer to the recipient during the temporal period using at least a portion of the deposit.

Abstract: Configuring data transfers based on electronic messages. A system includes a communication module, a processor, and a memory. The memory stores instructions that, when executed, configure the processor to: receive, from a client device, an authentication credential and associate the authentication credential with a client record. The processor identifies, based on delegated access to query a message account at a message server, a resource request message associated with the message account using a defined criteria. The processor obtains, based on the resource request message, a resource parameter to define a proposed resource transfer to a recipient entity. The processor generates and transmits, to the client device, a transfer request alert based on the proposed resource transfer for display at the client device. In response to receiving, from the client device, a selection of a selectable option, the processor allocates a resource to the recipient entity.

Abstract: Systems and methods of determining whether to initiate a pull of an accumulated data transfer amount are described. An accumulated data transfer amount for a periodic data transfer scheduled to be pushed at a future date is determined. A determination is made of whether an overall data amount in a storage location is expected to be greater at a date on or after the scheduled future date if a pull of the accumulated data transfer amount is performed before the scheduled future date than if a pull operation is not performed and the accumulated data transfer amount is sent at the scheduled future date. When the overall data amount in the storage location is expected to be greater at the scheduled future date if the pull of the accumulated data transfer amount is performed, a pull of the accumulated data transfer amount is initiated.

Abstract: Systems and methods for reversing a transfer of a digital asset are described. A method may include storing a token, the token providing for one or more transfers from a second storage location to a first storage location; receiving notification of a first transfer from the first storage location to the second storage location; detecting the first transfer from the first storage location to the second storage location; receiving a request for a reversal of the first transfer; determining an eligibility of the request for the reversal of the first transfer; and responsive to determining the eligibility of the request for the reversal of the first transfer, performing the reversal of the first transfer by executing, using the token, an offsetting transfer from the second storage location to the first storage location.

Abstract: A computer-implemented method is disclosed. The method includes: receiving, via a computing device of a transferor entity, a first request to process a transfer of resources associated with a first resource account, the first request indicating a maximum resource transfer amount for the transfer; generating a locked virtual allocation of resources associated with the first resource account, the virtual allocation representing a defined quantity of resources committed for the transfer; obtaining request data for a second request to transfer resources to a second resource account, the request data indicating a minimum requested resource amount; validating the second request based on identifying information of a recipient entity associated with the second request; determining that the first request and the second request satisfy a defined resource transfer condition; and in response to the determining, automatically granting, to the recipient entity, access to the virtual allocation of resources.

Abstract: In an aspect, the present application describes a computer system. The computer system includes a communications module and a processor coupled to the communications module. The computer system include a memory coupled to the processor storing instructions that, when executed by the computer system, cause the computer system to: receive, from an automated teller machine (ATM) and via the communications module, an indication of a deposit of a value instrument; save, in the memory, a retention instruction including an associated temporal period, the retention instruction preventing withdrawal of value instruments corresponding to an amount of the deposit; receive, via the communications module, an instruction to process a data transfer to a recipient, the data transfer to the recipient accessing at least a portion of the deposit; and process the data transfer to the recipient during the temporal period using at least a portion of the deposit.

Abstract: Systems and methods for account validation are disclosed. A method may include: receiving, at a validation computer program and from a client device, a request to validate payment information; querying, by the validation computer program, a plurality of validation systems with at least some of the payment information; receiving, at the validation computer program, a query response from each validation system; calculating, by the validation computer program, a risk score for each validation system based on a comparison between the payment information and the query response; weighting, by the validation computer program, the risk score for each validation system, wherein the weighting may be based on an accuracy of past risk scores for each validation system; aggregating, by the validation computer program, the weighted risk scores into a cumulative risk score; and outputting the cumulative risk score to the client device.

Abstract: In another aspect, a computer-implemented method is described. The method includes: detecting that an electronic device that has been previously configured to communicate with the ambient commerce system is at the ambient commerce premises, the electronic device associated with an entity; receiving, from the electronic device, a wallet identifier, the wallet identifier uniquely identifying a particular wallet that is to be used to complete an ambient commerce transaction; identifying, based on the sensor, one or more items that are to be associated with the ambient commerce transaction; and processing the ambient commerce transaction for the identified one or more items using the particular wallet identified by the wallet identifier.

Abstract: According to an aspect there is provided an ambient commerce system. The ambient commerce system may include a sensor at an ambient commerce premises. The ambient commerce system may further include a processor coupled to the sensor and a memory coupled to the processor. The memory may store processor-executable instructions which, when executed, cause the processor to: detect, based on an output of the sensor at the ambient commerce premises, engagement of an entity with a first item satisfying first predetermined criteria; identify the entity; determine based on account data for the identified entity, a resource parameter for the identified entity; and when the resource parameter satisfies second predetermined criteria, generate a notification on an electronic device associated with the entity.

Abstract: According to an aspect there is provided an ambient commerce system. The ambient commerce system may include a sensor at an ambient commerce premises. The ambient commerce system may include a processor coupled to the one or more sensors. The ambient commerce system may include a memory coupled to the processor. The memory may store processor-executable instructions which, when executed, cause the processor to: detect, based on an output of one or more of the sensors, engagement of an entity with a restricted item; identify the entity; obtain at least a portion of a profile for the entity; determine, based on the at least a portion of the profile for the identified entity, eligibility for the entity to acquire the restricted item; and selectively generate, based on the determined eligibility for the entity, a notification on an electronic device associated with the entity.

Abstract: The invention was conceived to facilitate in the advancement in internal combustion engine driven generators. Generators today consist of either an inverter generator design or a synchronous alternator design. Both designs have their advantages and disadvantages. The inverter generator offers very precise AC power output, lower noise level, and lower fuel consumption rates but can’t handle heavy inductive loads well. The synchronous alternator offers slightly less precise AC power output, greater noise level, higher fuel consumption rates but can power heavy inductive loads very well. The invention incorporates both, known inverter generator design and known synchronous alternator design, connected to an internal combustion engine, to form a hybrid generator design.

Abstract: A method of manufacturing a printing cylinder. The method comprises providing a moulding apparatus comprising a cylindrical moulding vessel defining a moulding cavity (101). The vessel comprises at least one inlet for the ingress of moulding material. The method comprises performing an injection moulding operation comprising: injecting moulding material through the at least one inlet to substantially fill the moulding cavity with moulding material; and effecting hardening of the moulding material within the vessel (102). The method comprises removing the printing cylinder (103). At least part of the injection moulding operation is performed in the presence of an active pressure being applied to the moulding cavity.

Abstract: The embodiments disclose a method including providing an aerial drone coupled wirelessly to a social distancing application on a user digital device, wherein the drone is coupled to solar cell panels for recharging its batteries, providing a strobe light coupled to the drone for signaling an S.O.S.

Abstract: Systems and methods are provided for receiving a first request to access a first borrowed resource in association with a first account, determining that a second account that is associated with the first account has access to a first owned resource corresponding to the first borrowed resource, and in response to determining that the second account has access to the first owned resource, allowing access to the first borrowed resource via the first account; and restricting the first owned resource via the second account.

Abstract: The invention relates to new quinoline, pyridopyrazine, naphthyridine and quinazolinone derivative compounds, to pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds in the treatment of diseases, e.g. cancer.

Abstract: A vehicle thermal management system including an electric powertrain, a single thermal loop, and a controller is provided. The electric powertrain includes a high voltage battery. The single thermal loop is for managing thermal conditions of the high voltage battery and a vehicle cabin and may include a climate control system, a blower, and a front evaporator in fluid communication with the vehicle cabin. The controller is programmed to, responsive to detection of a climate control system off request, output a command to direct the blower to push air through a heater core to the vehicle cabin at a predetermined temperature such that a temperature within the vehicle cabin is maintained at a predetermined temperature and refrigerant continues to flow through the front evaporator. The system may include a vehicle cabin temperature sensor and an ambient temperature sensor, each in electrical communication with the controller.

Abstract: In a method for advanced identification of a customer, a customer may remotely place an order, intending to later go to a store to pick up the ordered item. The store may have a pick-up area (e.g., at the back of the store) where the customer can go to pick up the ordered item. To save the customer time, the customer may be identified when she enters the store so that an employee can obtain her ordered item and have it ready to pick up by the time the customer walks through the store and arrives at the pick-up area.