Abstract: The present invention relates to the use of (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid of formula (I), prefer-ably in form of one of its salts or solvates or hydrates, preferably (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid in form of monohydrate (I) of formula (I-M-I) or (5S)-{[2-(4-carboxyphenyl)ethyl][2-(2-{[3-chloro-4?-(trifluoromethyl)biphenyl-4-yl]methoxy}phenyl)-ethyl]-amino}-5,6,7,8-tetrahydroquinoline-2-carboxylic acid inform of mono hydrate (II) of formula (I-M-II), in the inhalative treatment of cardiopulmonary and pulmonary disorders, such as pulmonary arterial hypertension (P AH), chronic thromboembolic pulmonary hypertension (CTEPH) and pulmonary hypertension (PH) associated with chronic lung disease (PH group 3) such as pulmonary hypertension in chronic obstructive pulmo

Abstract: The present Disclosure is directed to methods for inhibiting or suppressing metastasis of a tumor in a mammalian subject using a cysteamine product, e.g., cysteamine or cystamine or a derivative thereof. Also described herein is a method for treating pancreatic cancer in a mammalian subject by administering a cysteamine product described herein.

Abstract: Configuration states for a computing device and/or associated peripherals (“profiles”) are stored in one or more non-volatile logic (“NVL”) arrays. Using the non-volatile sub-system for the computing device, triggers for reconfiguration of the respective device or peripherals are provided to an NVL array controller, which controls provision of the new profile(s) for the respective device or peripherals over a dedicated bus to a configuration register that stores the active profiles for the device and associated peripherals.

Abstract: A circuit includes a guard trigger circuit that includes a first input node adapted to be coupled to a first state signal, a second input node adapted to be coupled to a second state signal and an output node. The circuit also includes a reset synchronizer circuit that includes an input node coupled to the output node of the guard trigger circuit, a clock node adapted to be coupled to a clock signal and an output node. The circuit further includes a timeout circuit including an input node coupled to the output node of the reset synchronizer circuit, a clock node adapted to be coupled to the clock signal and an output node. The circuit still further includes a reset requestor circuit that includes a first input node coupled to the output node of the guard trigger circuit, a second node coupled to the output node of the timeout circuit.

Abstract: A circuit includes a guard trigger circuit that includes a first input node adapted to be coupled to a first state signal, a second input node adapted to be coupled to a second state signal and an output node. The circuit also includes a reset synchronizer circuit that includes an input node coupled to the output node of the guard trigger circuit, a clock node adapted to be coupled to a clock signal and an output node. The circuit further includes a timeout circuit including an input node coupled to the output node of the reset synchronizer circuit, a clock node adapted to be coupled to the clock signal and an output node. The circuit still further includes a reset requestor circuit that includes a first input node coupled to the output node of the guard trigger circuit, a second node coupled to the output node of the timeout circuit.

Abstract: A digital system includes a non-volatile calculating register having a set of latches configured to perform a calculation. A set of non-volatile storage cells is coupled to the set of latches. Access detection logic is coupled to the calculating register and is operable to initiate a calculation of a next value by the calculating register each time the calculating register is accessed by an accessing module. The access detection logic is operable to cause the next value to be stored in the set of non-volatile storage cells at the completion of the calculation as an atomic transaction. After a power loss or other restore event, the contents of the calculating register may be restored from the non-volatile storage cells.

Abstract: A digital system includes a non-volatile calculating register having a set of latches configured to perform a calculation. A set of non-volatile storage cells is coupled to the set of latches. Access detection logic is coupled to the calculating register and is operable to initiate a calculation of a next value by the calculating register each time the calculating register is accessed by an accessing module. The access detection logic is operable to cause the next value to be stored in the set of non-volatile storage cells at the completion of the calculation as an atomic transaction. After a power loss or other restore event, the contents of the calculating register may be restored from the non-volatile storage cells.

Abstract: The invention allows an invited recipient to enter a security-protected system such as a website without traditional authentication by providing the security-protected system with a pre-arranged host-initiated authentication on behalf of the recipient. An invite message advises the recipient of the invited action, which may be as simple as entering the system or performing a task within the system. The recipient accepts the invitation by affirmatively responding to the invite message which includes the unique code to identify the recipient. Upon receipt of the affirmative response with the unique code from the recipient, the system platform executes algorithms which assess the risk of completing the action with the invited recipient, and if appropriate, provides the authentication to the security-protected system which will allow the recipient to take the invited action without providing additional authentication, such as a password.

Abstract: A circuit includes a guard trigger circuit that includes a first input node adapted to be coupled to a first state signal, a second input node adapted to be coupled to a second state signal and an output node. The circuit also includes a reset synchronizer circuit that includes an input node coupled to the output node of the guard trigger circuit, a clock node adapted to be coupled to a clock signal and an output node. The circuit further includes a timeout circuit including an input node coupled to the output node of the reset synchronizer circuit, a clock node adapted to be coupled to the clock signal and an output node. The circuit still further includes a reset requestor circuit that includes a first input node coupled to the output node of the guard trigger circuit, a second node coupled to the output node of the timeout circuit.

Abstract: Configuration states for a computing device and/or associated peripherals (“profiles”) are stored in one or more non-volatile logic (“NVL”) arrays. Using the non-volatile sub-system for the computing device, triggers for reconfiguration of the respective device or peripherals are provided to an NVL array controller, which controls provision of the new profile(s) for the respective device or peripherals over a dedicated bus to a configuration register that stores the active profiles for the device and associated peripherals.

Abstract: Configuration states for a computing device and/or associated peripherals (“profiles”) are stored in one or more non-volatile logic (“NVL”) arrays. Using the non-volatile sub-system for the computing device, triggers for reconfiguration of the respective device or peripherals are provided to an NVL array controller, which controls provision of the new profile(s) for the respective device or peripherals over a dedicated bus to a configuration register that stores the active profiles for the device and associated peripherals.

Abstract: A digital system includes a non-volatile calculating register having a set of latches configured to perform a calculation. A set of non-volatile storage cells is coupled to the set of latches. Access detection logic is coupled to the calculating register and is operable to initiate a calculation of a next value by the calculating register each time the calculating register is accessed by an accessing module. The access detection logic is operable to cause the next value to be stored in the set of non-volatile storage cells at the completion of the calculation as an atomic transaction. After a power loss or other restore event, the contents of the calculating register may be restored from the non-volatile storage cells.

Abstract: A digital system includes a non-volatile calculating register having a set of latches configured to perform a calculation. A set of non-volatile storage cells is coupled to the set of latches. Access detection logic is coupled to the calculating register and is operable to initiate a calculation of a next value by the calculating register each time the calculating register is accessed by an accessing module. The access detection logic is operable to cause the next value to be stored in the set of non-volatile storage cells at the completion of the calculation as an atomic transaction. After a power loss or other restore event, the contents of the calculating register may be restored from the non-volatile storage cells.

Abstract: Configuration states for a computing device and/or associated peripherals (“profiles”) are stored in one or more non-volatile logic (“NVL”) arrays. Using the non-volatile sub-system for the computing device, triggers for reconfiguration of the respective device or peripherals are provided to an NVL array controller, which controls provision of the new profile(s) for the respective device or peripherals over a dedicated bus to a configuration register that stores the active profiles for the device and associated peripherals.

Abstract: Configuration states for a computing device and/or associated peripherals (“profiles”) are stored in one or more non-volatile logic (“NVL”) arrays. Using the non-volatile sub-system for the computing device, triggers for reconfiguration of the respective device or peripherals are provided to an NVL array controller, which controls provision of the new profile(s) for the respective device or peripherals over a dedicated bus to a configuration register that stores the active profiles for the device and associated peripherals.

Abstract: Configuration states for a computing device and/or associated peripherals (“profiles”) are stored in one or more non-volatile logic (“NVL”) arrays. Using the non-volatile sub-system for the computing device, triggers for reconfiguration of the respective device or peripherals are provided to an NVL array controller, which controls provision of the new profile(s) for the respective device or peripherals over a dedicated bus to a configuration register that stores the active profiles for the device and associated peripherals.

Abstract: A processing device boots or wakes using non-volatile logic element (NVL) array(s) that store a machine state. A standard boot sequence is used to restore a first portion of data. A second portion of data is restored, in parallel with the standard boot sequence, from the NVL array(s). A data corruption check is performed on the second portion of data. If the second data is valid, a standard boot sequence is used to restore a third portion of data. If the second data is invalid or the boot is an initial boot, a standard boot sequence is executed to determine the second portion of data, which is then stored in the NVL array(s). The processing device restores the second portion of the data during a portion of the boot/wake process that is not reading data from other non-volatile devices to avoid overloading the respective power domain.

Abstract: A digital system includes a non-volatile calculating register having a set of latches configured to perform a calculation. A set of non-volatile storage cells is coupled to the set of latches. Access detection logic is coupled to the calculating register and is operable to initiate a calculation of a next value by the calculating register each time the calculating register is accessed by an accessing module. The access detection logic is operable to cause the next value to be stored in the set of non-volatile storage cells at the completion of the calculation as an atomic transaction. After a power loss or other restore event, the contents of the calculating register may be restored from the non-volatile storage cells.

Abstract: A processing device boots or wakes using non-volatile logic element (NVL) array(s) that store a machine state. A standard boot sequence is used to restore a first portion of data. A second portion of data is restored, in parallel with the standard boot sequence, from the NVL array(s). A data corruption check is performed on the second portion of data. If the second data is valid, a standard boot sequence is used to restore a third portion of data. If the second data is invalid or the boot is an initial boot, a standard boot sequence is executed to determine the second portion of data, which is then stored in the NVL array(s). The processing device restores the second portion of the data during a portion of the boot/wake process that is not reading data from other non-volatile devices to avoid overloading the respective power domain.

Abstract: A bonded structure including one or more substrates bonded together with a tackified amorphous poly-alpha-olefin adhesive composition. One method of making such a bonded structure is carried out by applying a tackified amorphous poly-alpha-olefin adhesive composition to one or more substrates at a temperature of about 170 degrees Celsius or lower, and joining the substrates to themselves or to one another. The bonded structure has a dynamic peel strength between about 400 and about 1000 grams per 25 millimeters. The bonding efficiency of the bonded structure renders the bonded structure suitable for incorporation into a variety of articles, including personal care products, health/medical products, and household/industrial product, for example.