Patents by Inventor Mark Keegan
Mark Keegan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20160279755Abstract: An apparatus for reconditioning wheels, the apparatus including: a trolley mounted base; and a reconditioning assembly rotatably mounted to the base, the reconditioning assembly including at least one reconditioning element.Type: ApplicationFiled: March 16, 2016Publication date: September 29, 2016Applicant: Vehicle Inspection Systems, Inc.Inventors: Mark Spaile, Arthur Stephen Withington, Mark Keegans
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Patent number: 8679313Abstract: A method and apparatus for continuously separating or concentrating molecules that includes flowing two fluids in laminar flow through an electrical field and capturing at one of three outputs a fluid stream having a different concentration of molecules.Type: GrantFiled: January 19, 2010Date of Patent: March 25, 2014Assignee: The Charles Stark Draper Laboratory, Inc.Inventors: Jason O. Fiering, Mark Keegan
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Publication number: 20100116657Abstract: A method and apparatus for continuously separating or concentrating molecules that includes flowing two fluids in laminar flow through an electrical field and capturing at one of three outputs a fluid stream having a different concentration of molecules.Type: ApplicationFiled: January 19, 2010Publication date: May 13, 2010Applicant: The Charles Stark Draper Laboratory, Inc.Inventors: Jason Fiering, Mark Keegan
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Publication number: 20080237044Abstract: A method and apparatus for continuously separating or concentrating molecules that includes flowing two fluids in laminar flow through an electrical field and capturing at one of three outputs a fluid stream having a different concentration of molecules.Type: ApplicationFiled: March 28, 2007Publication date: October 2, 2008Applicant: The Charles Stark Draper Laboratory, Inc.Inventors: Jason Fiering, Mark Keegan
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Patent number: 6962006Abstract: Methods and apparatus are provided for making particles comprising: (a) spraying an emulsion, solution, or suspension, which comprises a solvent and a bulk material (e.g., a pharmaceutical agent), through an atomizer and into a primary drying chamber, having a drying gas flowing therethrough, to form droplets comprising the solvent and bulk material dispersed in the drying gas; (b) evaporating, in the primary drying chamber, at least a portion of the solvent into the drying gas to solidify the droplets and form particles dispersed in drying gas; and (c) flowing the particles and at least a portion of the drying gas through a jet mill to deagglomerate or grind the particles. By coupling spray drying with “in-line” jet milling, a single step process is created from two separate unit operations, and an additional collection step is advantageously eliminated. The one-step, in-line process has further advantages in time and cost of processing.Type: GrantFiled: December 19, 2002Date of Patent: November 8, 2005Assignee: Acusphere, Inc.Inventors: Donald E. Chickering, III, Sridhar Narasimhan, David Altreuter, Paul Kopesky, Mark Keegan, Julie A. Straub, Howard Bernstein
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Publication number: 20050209099Abstract: Methods and apparatus are provided for making particles comprising: (a) spraying an emulsion, solution, or suspension, which comprises a solvent and a bulk material (e.g., a pharmaceutical agent), through an atomizer and into a primary drying chamber, having a drying gas flowing therethrough, to form droplets comprising the solvent and bulk material dispersed in the drying gas; (b) evaporating, in the primary drying chamber, at least a portion of the solvent into the drying gas to solidify the droplets and form particles dispersed in drying gas; and (c) flowing the particles and at least a portion of the drying gas through a jet mill to deagglomerate or grind the particles. By coupling spray drying with “in-line” jet milling, a single step process is created from two separate unit operations, and an additional collection step is advantageously eliminated. The one-step, in-line process has further advantages in time and cost of processing.Type: ApplicationFiled: June 2, 2005Publication date: September 22, 2005Inventors: Donald Chickering, Sridhar Narasimhan, David Altreuter, Paul Kopesky, Mark Keegan, Julie Straub, Howard Bernstein
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Patent number: 6921458Abstract: Methods and apparatus are provided for making particles comprising: (a) spraying an emulsion, solution, or suspension, which comprises a solvent and a bulk material (e.g., a pharmaceutical agent), through an atomizer and into a primary drying chamber, having a drying gas flowing therethrough, to form droplets comprising the solvent and bulk material dispersed in the drying gas; (b) evaporating, in the primary drying chamber, at least a portion of the solvent into the drying gas to solidify the droplets and form particles dispersed in drying gas; and (c) flowing the particles and at least a portion of the drying gas through a jet mill to deagglomerate or grind the particles. By coupling spray drying with “in-line” jet milling, a single step process is created from two separate unit operations, and an additional collection step is advantageously eliminated. The one-step, in-line process has further advantages in time and cost of processing.Type: GrantFiled: January 7, 2004Date of Patent: July 26, 2005Assignee: Acusphere, Inc.Inventors: Donald E. Chickering, III, Sridhar Narasimhan, David Altreuter, Paul Kopesky, Mark Keegan, Julie A. Straub, Howard Bernstein
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Patent number: 6918991Abstract: Methods and apparatus are provided for making particles comprising: (a) spraying an emulsion, solution, or suspension, which comprises a solvent and a bulk material (e.g., a pharmaceutical agent), through an atomizer and into a primary drying chamber, having a drying gas flowing therethrough, to form droplets comprising the solvent and bulk material dispersed in the drying gas; (b) evaporating, in the primary drying chamber, at least a portion of the solvent into the drying gas to solidify the droplets and form particles dispersed in drying gas; and (c) flowing the particles and at least a portion of the drying gas through a jet mill to deagglomerate or grind the particles. By coupling spray drying with “in-line” jet milling, a single step process is created from two separate unit operations, and an additional collection step is advantageously eliminated. The one-step, in-line process has further advantages in time and cost of processing.Type: GrantFiled: January 7, 2004Date of Patent: July 19, 2005Assignee: Acusphere, Inc.Inventors: Donald E. Chickering, III, Sridhar Narasimhan, David Altreuter, Paul Kopesky, Mark Keegan, Julie A. Straub, Howard Bernstein
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Publication number: 20040139624Abstract: Methods and apparatus are provided for making particles comprising: (a) spraying an emulsion, solution, or suspension, which comprises a solvent and a bulk material (e.g., a pharmaceutical agent), through an atomizer and into a primary drying chamber, having a drying gas flowing therethrough, to form droplets comprising the solvent and bulk material dispersed in the drying gas; (b) evaporating, in the primary drying chamber, at least a portion of the solvent into the drying gas to solidify the droplets and form particles dispersed in drying gas; and (c) flowing the particles and at least a portion of the drying gas through a jet mill to deagglomerate or grind the particles. By coupling spray drying with “in-line” jet milling, a single step process is created from two separate unit operations, and an additional collection step is advantageously eliminated. The one-step, in-line process has further advantages in time and cost of processing.Type: ApplicationFiled: January 7, 2004Publication date: July 22, 2004Inventors: Donald E. Chickering, Sridhar Narasimhan, David Altreuter, Paul Kopesky, Mark Keegan, Julie A. Straub, Howard Bernstein
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Publication number: 20040134091Abstract: Methods and apparatus are provided for making particles comprising: (a) spraying an emulsion, solution, or suspension, which comprises a solvent and a bulk material (e.g., a pharmaceutical agent), through an atomizer and into a primary drying chamber, having a drying gas flowing therethrough, to form droplets comprising the solvent and bulk material dispersed in the drying gas; (b) evaporating, in the primary drying chamber, at least a portion of the solvent into the drying gas to solidify the droplets and form particles dispersed in drying gas; and (c) flowing the particles and at least a portion of the drying gas through a jet mill to deagglomerate or grind the particles. By coupling spray drying with “in-line” jet milling, a single step process is created from two separate unit operations, and an additional collection step is advantageously eliminated. The one-step, in-line process has further advantages in time and cost of processing.Type: ApplicationFiled: January 7, 2004Publication date: July 15, 2004Inventors: Donald E. Chickering, Sridhar Narasimhan, David Altreuter, Paul Kopesky, Mark Keegan, Julie A. Straub, Howard Bernstein
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Publication number: 20040118007Abstract: Methods and apparatus are provided for making particles comprising: (a) spraying an emulsion, solution, or suspension, which comprises a solvent and a bulk material (e.g., a pharmaceutical agent), through an atomizer and into a primary drying chamber, having a drying gas flowing therethrough, to form droplets comprising the solvent and bulk material dispersed in the drying gas; (b) evaporating, in the primary drying chamber, at least a portion of the solvent into the drying gas to solidify the droplets and form particles dispersed in drying gas; and (c) flowing the particles and at least a portion of the drying gas through a jet mill to deagglomerate or grind the particles. By coupling spray drying with “in-line” jet milling, a single step process is created from two separate unit operations, and an additional collection step is advantageously eliminated. The one-step, in-line process has further advantages in time and cost of processing.Type: ApplicationFiled: December 19, 2002Publication date: June 24, 2004Applicant: ACUSPHERE, INC.Inventors: Donald E. Chickering, Sridhar Narasimhan, David Altreuter, Paul Kopesky, Mark Keegan, Julie A. Straub, Howard Bernstein
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Patent number: 6223455Abstract: Improved spray drying apparati, and methods of use thereof, have been developed. The spray drying equipment includes a primary drying chamber and a secondary drying apparatus which includes tubing having a length sufficient to increase the contact time between the drying gas and the droplets/particles to dry the particles to the extent desired, at a drying rate and temperature which would be too low to provide adequate drying without the secondary drying apparatus. The secondary drying apparatus increases the drying efficiency of the spray dryer system without increasing the drying rate, while minimizing loss in yield The ratio of the length of tubing to the length of the primary drying chamber is at least 2:1. The tubing diameter is substantially smaller than the diameter of the primary drying chamber, such that the particles move at higher velocity through the tubing to minimize product losses.Type: GrantFiled: May 3, 1999Date of Patent: May 1, 2001Assignee: Acusphere, Inc.Inventors: Donald E. Chickering, III, Howard Bernstein, Mark Keegan, Greg Randall, Julie Straub
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Patent number: 6049061Abstract: A heater comprising a heating element embedded in a dielectric sheet, is disclosed. A leaf spring which is curved when relaxed, clamps the embedded heating element against a surface to be heated. The heater is optionally mounted on an internal surface of an enclosure. The heater is operable to a flux of about 3.9 kW-m.sup.2.Type: GrantFiled: October 20, 1998Date of Patent: April 11, 2000Assignee: Lucent Technologies Inc.Inventors: William George Gates, Martin Michael Mark Keegan
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Patent number: 6038129Abstract: An electronic apparatus having a heat dissipative external enclosure is disclosed. The external enclosure having a containment wall from which depend extended surfaces or fins having a length extending vertically and defining channels therebetween. The thickness of the enclosure between external surfaces of opposed containment walls varying between a relatively thin portion and a relatively thick portion to provide an interior space having a relatively narrow portion and a relatively wide portion to accommodate components or units of corresponding different extent. The fins having outer edges, spaced from the containment wall, and having plain first opposed surfaces adjacent their outer edges, the first surfaces including a first angle therebetween. The fins or parts of fins adjacent the relatively thin portion of the enclosure also having plain second opposed surfaces inwards of the first surfaces, the second surfaces including therebetween a second angle greater than the first angle.Type: GrantFiled: April 27, 1999Date of Patent: March 14, 2000Assignee: Lucent Technologies Inc.Inventors: Hamid Reza Falaki, William George Gates, Patrick Francis Hanlon, Martin Michael Mark Keegan, Daniel Peter Kelly