Abstract: The invention relates to fusion constructs and checkpoint inhibitors, methods of using fusion constructs and checkpoint inhibitors, and methods of treating undesirable or aberrant cell proliferation or hyperproliferative disorders, such as tumors, cancers, neoplasia and malignancies.

Abstract: A sub assembly for coupling to a drill string, the assembly comprising; a mandrel; a sleeve arranged to be co-axially positioned about said mandrel; a first stop arranged to prevent axial movement of the sleeve along the mandrel in a first direction; a second stop arranged to prevent axial movement of the sleeve in a second direction; wherein said second stop is releasably engageable from the mandrel.

Abstract: A sub assembly for coupling to a drill string, the assembly comprising; a mandrel; a sleeve arranged to be co-axially positioned about said mandrel; a first stop arranged to prevent axial movement of the sleeve along the mandrel in a first direction; a second stop arranged to prevent axial movement of the sleeve in a second direction; wherein said second stop is releasably engageable from the mandrel.

Abstract: This disclosure is directed to apparatuses, systems, and methods that can quickly and reliably determine a stationary or non-stationary change in temperature. During a simulated test of, for example, the heater system of an automated and/or high-speed composite material placement machine may be evaluated at any single location along a course whether a lay down material is heated below, at, or beyond its particular temperature requirements. Temperature measurements can be of a heat source that is moving at a rate from zero to over 3000 inches/minute. Temperature measurements of a moving heat source are reliable within a variance of approximately plus or minus 3° F. In addition, temperature measurements of a moving heat source on a laminated material may be had with a plurality of sensors along at least one direction and to various depths.

Abstract: The present invention relates to a reforming device. A reforming device according to the present invention includes a main body that is locked to bones of a human body and of which a length is extensible depending on growth of the human body; an external controller that transmits a wireless control signal for a length of the main body to be extended inside of the human body; and an internal controller that is mounted inside of the human body and extends the length of the main body depending on the wireless control signal.

Abstract: A card game apparatus 12 includes an image sensor 54. The image sensor photographs a design (31: FIG. 2) printed on a card 30. A photographic signal from the image sensor is sampled by a game processor 64, and is further re-sampled to form a photographic pixel data array. A ROM 66 is provided with a database (67A: FIG. 7) which is assigned a comparison data array and a card ID for each entry. By searching the database based on the photographic pixel data array, the processor 64 obtains one card ID and displays card data of the card identified by the card ID on a television monitor.