Patents by Inventor MARK KYLE MIMEE

MARK KYLE MIMEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • TUNING MICROBIAL POPULATIONS WITH PROGRAMMABLE NUCLEASES
    Publication number: 20150064138
    Abstract: Various aspects and embodiments of the invention are directed to methods and compositions for reversing antibiotic resistance or virulence in and/or destroying pathogenic microbial cells such as, for example, pathogenic bacterial cells. The methods include exposing microbial cells to a delivery vehicle with at least one nucleic acid encoding an engineered autonomously distributed circuit that contains a programmable nuclease targeted to one or multiple genes of interest.
    Type: Application
    Filed: September 3, 2014
    Publication date: March 5, 2015
    Applicant: MASSACHUSETTS INSTITUTE OF TECHNOLOGY
    Inventors: TIMOTHY KUAN-TA LU, ROBERT JAMES CITORIK, MARK KYLE MIMEE