Patents by Inventor Mark L. Borowsky

Mark L. Borowsky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Proteases
    Patent number: 6927056
    Abstract: The invention provides a human cysteine proteases and polynucleotides which encode those proteases. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists, as well as methods for diagnosing, treating, or preventing disorders associated with aberrant expression of cysteine proteases.
    Type: Grant
    Filed: September 6, 2001
    Date of Patent: August 9, 2005
    Assignee: Incyte Corporation
    Inventors: Stephen Todd, Angelo M. Delegeane, Ameena R. Gandhi, Danniel B. Nguyen, April J. A. Hafalia, Liam Kearney, Yan Lu, Ernestine A. Lee, Narinder K. Chawla, Debopriya Das, Chandra S. Arvizu, Monique G. Yao, Deborah A. Kallick, Vicki S. Elliott, Li Ding, Henry Yue, Roopa M. Reddy, Dyung Aina M. Lu, Jayalaxmi Ramkumar, Junming Yang, Catherine M. Tribouley, Neil Burford, Mariah R. Baughn, Preeti G. Lal, Mark L. Borowsky, Farrah A. Khan, Rajagopal Gururajan, Y. Tom Tang, Janice K. Au-Young, Bridget A. Warren, Roberto Hernandez, Brendan M. Duggan
  • Molecules for disease detection and treatment
    Publication number: 20040249128
    Abstract: Various embodiments of the invention provide human molecules for disease detection and treatment (MDDT) and polynucleotides which identify and encode MDDT. Embodiments of the invention also provide expression vectors, host cells, anti-bodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of MDDT.
    Type: Application
    Filed: July 19, 2004
    Publication date: December 9, 2004
    Inventors: Michael B Thornton, Janice K Au-Young, Yalda Azimzai, Olga Bandman, Ines Barroso, Mariah R Baughn, Shanya D Becha, Mark L Borowsky, Li Ding, Brendan M Duggan, Vicki S Elliott, Brooke M Emerling, Ian J Forsythe, Ameena R Gandhi, Kimberly J Gietzen, Ann E Gorvad, Jennifer A Griffin, Rajagopal Gururajan, April J A Hafalia, Huijun Z Ring, Craig H Ison, Karen Anne Jones, Preeti G Lal, Ernestine A Lee, Sally Lee, Joana X Li, Dyung Aina M Lu, Joseph P. Marquis, Patricia M. Lehr-Mason, Narinder K. Chawla, Chandra S. Arvizu, Bharati Sanjanwala, Thierry R. Sornasse, Anita Swarnakar, Y Tom Tang, Kavitha Thangavelu, Bao Tran, Uyen K. Tran, Bridget A. Warren, Yuming Xu, Monique G. Yao, Henry Yue, Huibin Yue, Yeganeh Zebarjadian, Hsin-Ru Chang
  • Receptors and membrane associated proteins
    Publication number: 20040248251
    Abstract: Various embodiments of the invention provide human receptors and membrane-associated proteins (REMAP) and polynucleotides which identify and encode REMAP. Embodiments of the invention also provide expression vectors, host cells, anti-bodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of REMAP.
    Type: Application
    Filed: July 7, 2004
    Publication date: December 9, 2004
    Inventors: Preeti G Lal, Cynthia D Honchell, Ian J Forsythe, Narinder K Chawla, Y Tom Tang, Mark L Borowsky, Ines Barroso, Henry Yue, Bridget A Warren, Kavitha Thangavelu, Kimberly J Gietzen, Yalda Azimzai, Ernestine A Lee, Mariah R Baughn, Ann E Gorvad, Brendan M Duggan, Bao Tran, Joana X Li, Thomas W Richardson, Vicki S Elliott, Yeganeh Zebarjadian, Uyen K Tran, Monique G Yao, David P Peterson, Wen Luo, Lehr-Mason Patricia
  • Transporters and ion channels
    Publication number: 20040224911
    Abstract: The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
    Type: Application
    Filed: February 3, 2003
    Publication date: November 11, 2004
    Inventors: Henry Yue, Michael B. Thornton, Jayalxmi Ramkumar, Y.Tom Tang, Yalda Azimzai, Mariah R. Baughn, Junming Yang, Monique G. Yao, Preeti G. Lal, Narinder K. Chawla, Ameena R. Gandhi, April J. A. Hafalia, Danniel B. Nguyen, Chandra S. Arvizu, Vicki S. Elliott, Catherine M. Tribouley, Dyung Aina M. Lu, Yuming Xu, Roopa M. Reddy, Roberto Hernandez, Mark L. Borowsky, Terence P. Lo, Yan Lu, Jennifer L. Policky, Barrie D. Greene, Madhusudan M. Sanjanwala, Brigitte E. Raumann, Neil Burford, Craig H. Ison, Ernestine A. Lee, Li Ding, Debopriya Das, Deborah A. Kallick, Farrah A. Khan, Jeffrey J. Seilhamer
  • Neurotransmisson-associated proteins
    Publication number: 20040203014
    Abstract: Various embodiments of the invention provide human neurotransmission-associated proteins (NTRAN) and polynucleotides which identify and encode NTRAN. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NTRAN.
    Type: Application
    Filed: March 12, 2004
    Publication date: October 14, 2004
    Inventors: Cynthia D. Honchell, Bridget A. Warren, Mark L. Borowsky, Jennifer A. Griffin, Joana X. Li, Soo Yeun Lee, Henry Yue, Ian J. Forsythe, Joseph P. Marquis, Kimberly J. Gietzen, Mariah R. Baughn, Uyen K. Tran, Patricia M. Lehr-Mason, Y. Tom Tang, Jayalaxmi Ramkumar, Brooke M. Emerling, Ernestine A. Lee, Vicki S. Elliott, April J.A. Hafalia, Brendan M. Duggan, Narinder K. Chawla, Amy E. Kable, Hsin-Ru Chang, Reena Khare, Shanya D. Becha, Pei Jin, Sally Lee
  • Kinases and phosphatases
    Publication number: 20040203097
    Abstract: The invention provides human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.
    Type: Application
    Filed: November 18, 2003
    Publication date: October 14, 2004
    Inventors: Henry Yue, Dyung Aina M Lu, Yalda Azimzai, Li Ding, Ernestine A Lee, April J A Hafalia, Shanya D Becha, Y Tom Tang, Preeti G. Lal, Jennifer A Griffin, Rajagopal Gururajan, Jayalaxmi Ramkumar, Vicki S Elliott, Chandra S Arvizu, Wen Luo, Anita Swarnakar, Brendan M Duggan, Uyen K Tran, Narinder K Chawla, Ameena E Gandhi, Monique G Yao, Farrah A Khan, Mariah R Baughn, Mark L Borowsky, Yeganeh Zebarjadian, Thomas W Richardson, Joseph P Marquis, David Chien, Pei Jin
  • Nucleic acid-associated proteins
    Publication number: 20040171012
    Abstract: Various embodiments of the invention provide human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. Embodiments of the invention also provide expression vectors, host cells, antibodies, agonists, and antagonists. Other embodiments provide methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
    Type: Application
    Filed: December 1, 2003
    Publication date: September 2, 2004
    Inventors: Henry Yue, Y Tom Tang, Mariah R Baughn, Shanya D Becha, Bridget A Warren, Narinder K Chawla, Preeti G Lal, Ernestine A Lee, April J A Hafalia, Thomas W Richardson, Jennifer A Griffin, Brooke M Emerling, Jayalaxmi Ramkumar, Huibin Yue, Anita Swarnakar, Bao Tran, Joana X Li, Monique G Yao, Junming Yang, Craig H Ison, Ian J Forsythe, Cynthia D Honchell, Vicki S Elliott, Yan Lu, Li Ding, Wen Luo, Yu-Mei E Wang, Neil Burford, Mark L Borowsky, Danniel B Nguyen, Anna M Chinn, Amy E Kable, Chandra S Arvizu
  • G-protein coupled receptors
    Publication number: 20040152157
    Abstract: The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
    Type: Application
    Filed: October 27, 2003
    Publication date: August 5, 2004
    Inventors: Michael B. Thornton, Narinder K. Chawla, Kimberly J. Gietzen, Anita Swarnakar, Mariah R Baughn, Bridget A Warren, Jayalaxmi Ramkumar, Monique G Yao, Pei Jin, Deborah A Kallick, Thomas W Richardson, Mark L Borowsky, Richard C Graul, Junming Yang, Li Ding, Glenn K Fu
  • Nucleic acid-associated proteins
    Publication number: 20040152877
    Abstract: The invention provides human nucleic acid-associated proteins (NAAP) and polynucleotides which identify and encode NAAP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of NAAP.
    Type: Application
    Filed: February 25, 2004
    Publication date: August 5, 2004
    Inventors: Jennifer L. Hillman, Mariah R. Baughn, Anita Swarnakar, Henry Yue, Vicki S. Elliott, Neil Burford, Li Ding, Y. Tom Tang, Soo Yeun Lee, Yalda Azimzai, Narinder K. Walia, Kimberly J. Gietzen, Jennifer A. Griffin, Preeti G. Lal, Junming Yang, Mark L. Borowsky, Thomas W. Richardson, Huibin Yue, Shanya Becha, Ian Forsythe, Karen Anne Jones, Bridget A. Warren, Kavitha Thangavelu, Cynthia D. Honchell, Helen E. Jolley, April J.A. Hafalia, Huijun Z. Ring
  • G-protein coupled receptors
    Publication number: 20040138416
    Abstract: The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
    Type: Application
    Filed: September 30, 2003
    Publication date: July 15, 2004
    Inventors: Michael B Thornton, Monique G Yao, Thomas W Richardson, Anita Swarnakar, Deborah A Kallick, Craig H Ison, Narinder K Chawla, Ameena R Gandhi, Ernestine A Lee, Vicki S Elliott, April J A Hafalia, Janice K Au-Young, Jennifer A Griffin, Mariah R Baughn, Farrah A Khan, Shanya D Becha, Yan Lu, Chandra S Arvizu, Mark L Borowsky, Preeti G Lal, Jayalaxmi Ramkumar, Brooke M Emerling, Roderick T Walsh, Henry Yue, Neil Burford, Richard C Graul
  • Proteins Associated with cell growth, differentiation, and death
    Publication number: 20040132043
    Abstract: The invention provides human proteins associated with cell growth, differentiation, and death (CGDD) and polynucleotides which identify and encode CGDD. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of CGDD.
    Type: Application
    Filed: October 6, 2003
    Publication date: July 8, 2004
    Inventors: Yalda Azimzai, Janice K Au-Young, Sajeev Batra, Mariah R Baughn, Shanya D Becha, Mark L Borowsky, Neil Burford, Li Ding, Vicki S Elliott, Brooke M Emerling, Ameena R Gandhi, Kimberly J Gietzen, Jennifer A Griffin, April J A Hafalia, Cynthia D Honchell, Preeti G Lal, Soo Yeun Lee, Dyung Aina M Lu, Chandra S Arvizu, Jayalaxmi Ramkumar, Roopa M Reddy, Madhusudan M Sanjanwala, Y Tom Tang, Narinder K Chawla, Yu-Mei E Wang, Bridget A Warren, Yuming Xu, Junming Yang, Monique G Yao, Henry Yue, Yeganeh Zebarjadian
  • Kinases and phosphatases
    Publication number: 20040110180
    Abstract: The invention provides human kinases and phosphatases (KPP) and polynucleotides which identify and encode KPP. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of KPP.
    Type: Application
    Filed: October 1, 2003
    Publication date: June 10, 2004
    Inventors: Shirley Recipon, John D. Burrill, Gregory A. Marcus, Kurt A. Zingler, Y Tom Tang, Michael M. Thornton, Mark L. Borowsky, Mariah R. Baughn, Neil Burford, Soo Yeun Lee, Olga Bandman, April J.A. Hafalia, Monique G Yao, Jayalaxmi Ramkumar, Narinder K. Chawla, Dyung Aina M. Lu, Chandra S. Arvizu, Ison H. Craig, Li Ding, Yan Lu, Rajagopal Gururajan, Roderick T. Walsh, Ameena R. Gandhi, Anita Swarnakar, Ian J. Forsythe, Henry Yue, Janice K. Au-Young, Vicki S. Elliott, Sally Lee
  • Proteases
    Publication number: 20040091962
    Abstract: The invention provides human proteases (PRTS) and polynucleotides which identify and encode PRTS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PRTS.
    Type: Application
    Filed: January 21, 2003
    Publication date: May 13, 2004
    Inventors: Angelo M Delegeane, Ameena R Gandhi, April J A Hafalia, Dyung Aina M Lu, Chandra S Arvizu, Catherine M Tribouley, Debopriya Das, Deborah A Kallick, Danniel B Nguyen, Ernestine A Lee, Farrah A Khan, Henry Yue, Janice K Au-Young, Jennifer A Griffin, Jennifer L Policky, Jayalaxmi Ramkumar, Junming Yang, Kavitha Thangavelu, Li Ding, Liam Kearney, Mariah R Baughn, Mark L Borowsky, Madhusudan M Sanjanwala, Monique G Yao, Neil Burford, Narinder K Chawla, Preeti G Lal, Sally Lee, Stephen Todd, Terence P Lo, Y Tom Tang, Vicki S Elliott, Yalda Azimzai, Yan Lu
  • Drug metabolizing enzymes
    Publication number: 20040086887
    Abstract: The invention provides human drug metabolizing enzymes (DME) and polynucleotides which identify and encode DME. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of DME.
    Type: Application
    Filed: March 27, 2003
    Publication date: May 6, 2004
    Inventors: Yalda Azimzai, Mariah R Baughn, Mark L Borowsky, Li Ding, Brendan M Duggan, Vicki S Elliott, Ameena R Gandhi, Jennifer A Griffin, April J A Hafalia, Craig H Ison, Farrah A Khan, Preeti G Lal, Ernestine A Lee, Dyung Aina M Lu, Danniel B Nguyen, Chandra S Arvizu, Jennifer L Policky, Jayalaxmi Ramkumar, Huizun Z Ring, Madhusudan M Sanjanwala, Y Tom Tang, Catherine M Tribouley, Narinder K Chawla, Roderick T Walsh, Bridget A Warren, Yuming Xu, Junming Yang, Monique G Yao, Henry Yue
  • Protein modification and maintenance molecules
    Publication number: 20040077048
    Abstract: The invention provides human protein modification and maintenance molecules (PMMM) and polynucleotides which identify and encode PMMM. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PMMM.
    Type: Application
    Filed: July 31, 2003
    Publication date: April 22, 2004
    Inventors: Bridget A. Warren, Cynthia D. Honchell, Yan Lu, Narinder K. Chawla, Neil Burford, Angelo M. Delegeane, Ameena R. Gandhi, Mariah R. Baughn, Jennifer A. Griffin, Kimberly J. Gietzen, Dyung Aina M. Lu, Craig H. Ison, Jayalaxmi Ramkumar, Y Tom Tang, Preeti G. Lal, Mark L. Borowsky, Brendan M. Duggan, April J A Hafalia, Chandra S. Arvizu, Kavitha Thangavelu, Monique G. Yao, Vicki S. Elliott, Li Ding, Henry Yue, Sally Lee, Anita Swarnakar, Uyen K. Tan, Yuming Xu
  • G-protein coupled receptors
    Publication number: 20040072996
    Abstract: The invention provides human G-protein coupled receptors (GCREC) and polynucleotides which identify and encode GCREC. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of GCREC.
    Type: Application
    Filed: August 21, 2003
    Publication date: April 15, 2004
    Inventors: Preeti G Lal, Mariah R. Baughn, April J.A. Hafalia, Danniel B. Nguyen, Ameena R. Gandhi, Deborah A. Kallick, Jennifer A. Griffin, Henry Yue, Farrah A. Khan, Chandra S. Arvizu, Dyung Aina M. Lu, Catherine M. Tribouley, Yan Lu, Narinder K. Chawla, Richard C. Graul, Monique G. Yao, Junming Yang, Jayakaxmi Ramkumar, Janice K. Au-Young, Vicky S. Elliott, Roberto Hernandez, Roderick T. Walsh, Mark L. Borowsky, Michael R. Thornton, Ann He
  • Extracellular matrix and cell adhesion molecules
    Publication number: 20040053824
    Abstract: The invention provides human extracellular matrix and cell adhesion molecules (ECMCAD) and polynucleotides which identity and encode ECMCAD. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of ECMCAD.
    Type: Application
    Filed: December 18, 2002
    Publication date: March 18, 2004
    Inventors: Y Tom Tang, Henry Yue, Yalda Azimzai, Ann He, Terence P Lo, Daniel B Nguyen, John D Burrill, Gregory A Marcus, Kurt A Zingler, Ameena R Gandhi, Liam Kearney, Neil Burford, Monique G Yao, Narinder K Chawla, Vicki S Elliott, Chandra S Arvizu, Mariah R Baughn, April J A Hafalia, Jennifer L Policky, Janice K Au-Young, Yan Lu, Mark L Borowsky, Dyung Aina M Lu, Jayalaxmi Ramkumar, Junming Yang, Rajagopal Gururajan, Bridget A Warren, Kimberly J Gietzen, Yuming Xu, Deborah A Kallick, Ernestine A Lee, Kavitha Thangavelu, Angelo M Delegeane, Sally Lee, Sajeev Batra, Preetr G. Lal, Farrah A. Khan
  • Proteases
    Publication number: 20040053269
    Abstract: The invention provides human proteases (PRTS) and polynucleotides which identify and encode PRTS. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PRTS.
    Type: Application
    Filed: March 4, 2003
    Publication date: March 18, 2004
    Inventors: Stephen Todd, Angelo M Delegeane, Ameena R Gandhi, Danniel B Nguyen, April J A Hafalia, Liam Kearney, Yan Lu, Ernestine A Lee, Narinder K Chawla, Debopriya Das, Chandra S Arvizu, Monique G Yao, Deborah A Kallick, Vicki S Elliott, Li Ding, Henry Yue, Roopa M Reddy, Dyung Aina M Lu, Jayalaxmi Ramkumar, Junming Yang, Catherine M Tribouley, Neil Burford, Mariah R Baughn, Preeti G Lal, Mark L Borowsky, Farrah A Khan, Rajagopal Gururajan, Y Tom Tang, Janice K Au-Young, Bridget A Warren, Roberto Hernandez, Brendan M Duggan
  • Human kinases
    Publication number: 20040053394
    Abstract: The invention provides human human kinases (PKIN) and polynucleotides which identify and encode PKIN. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of PKIN.
    Type: Application
    Filed: April 18, 2003
    Publication date: March 18, 2004
    Inventors: Rajagopal Gururajan, Mariah R Baughn, Narinder K Chawla, Vicki S Elliott, Yuming Xu, Chandra S Arvizu, Monique G Yao, Jayalaxmi Ramkumar, Li Ding, Y Tom Tang, April J A Hafalia, Danniel B Nguyen, Ameena R Gandhi, Yan Lu, Henry Yue, Neil Burford, Olga Bandman, Catherine M Tribouley, Preeti G Lal, Shirley A Recipon, Dyung Aina M Lu, Mark L Borowsky, Michael B Thornton, Anita Swarnakar, Kavitha Thangavelu, Farrah A Khan, Craig H Ison
  • Transporters and ion channels
    Publication number: 20040053258
    Abstract: The invention provides human transporters and ion channels (TRICH) and polynucleotides which identify and encode TRICH. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for diagnosing, treating, or preventing disorders associated with aberrant expression of TRICH.
    Type: Application
    Filed: September 22, 2003
    Publication date: March 18, 2004
    Inventors: Brigitte E. Raumann, Michael B. Thornton, Li Ding, Henry Yue, Y Tom Tang, Lee Harland, Neil Burford, Barrie D. Greene, Madhusudan M. Sanjanwala, Mariah R. Baughn, Monique G. Yao, Junming Yang, Chandra S. Arvizu, Ameena R. Gandhi, April J.A. Hafalia, Catherine M. Tribouley, Narinder K. Chawla, Janice K. Au-Young, Roderick T. Walsh, Jayalaxmi Ramkumar, Yan Lu, Dyung Aina M. Lu, Yalda Azimzai, Preeti G Lal, Vicki S. Elliott, Danniel B. Nguyen, Yuming Xu, Jeffrey J. Seilhamer, Mark L. Borowsky, Farrah A. Khan, Liam Kearney, Kavitha Thangavelu, Debopriya Das, Jennifer L. Policky