Patents by Inventor Mark L. Faupel
Mark L. Faupel has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20140221846Abstract: An apparatus to interrogate, receive, and analyze full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics. The apparatus includes a base unit having illumination, detection and control sub-units, the illumination sub-unit providing illumination optical energy for illuminating a target tissue and the detection sub-unit detecting tissue characteristics of a target tissue, a separate tissue interface unit, and a pathway coupling the base unit and the tissue interface unit. The system and apparatus may also include a tube for maintaining the distance between the tissue and units and for surrounding the tissue to prevent patient movement from being transmitted to the tissue.Type: ApplicationFiled: November 6, 2013Publication date: August 7, 2014Inventors: Shabbir Bambot, Mark L. Faupel, Anant Agrawal, Keith D. Ignotz, Andrew Fordham
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Patent number: 8712515Abstract: Novel methods and apparatus for diagnosing or screening disease states in living organisms by the measurement and analysis of extremely low frequency electromagnetic fields, particularly extremely low frequency alternating current. The measurement of such fields is performed at a single point or at several test points on or in the body and compared to one or more reference. Information in the time-varying electromagnetic field is collected, then processed by diagnostic or screening algorithms to provide information about the disease state of the tissue being assessed.Type: GrantFiled: August 13, 2009Date of Patent: April 29, 2014Inventor: Mark L. Faupel
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Patent number: 8644912Abstract: An apparatus to interrogate, receive, and analyze full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics. The apparatus includes a base unit having illumination, detection and control sub-units, the illumination sub-unit providing illumination optical energy for illuminating a target tissue and the detection sub-unit detecting tissue characteristics of a target tissue, a separate tissue interface unit, and a pathway coupling the base unit and the tissue interface unit. The system and apparatus may also include a tube for maintaining the distance between the tissue and units and for surrounding the tissue to prevent patient movement from being transmitted to the tissue.Type: GrantFiled: August 22, 2011Date of Patent: February 4, 2014Assignee: SpectRx, Inc.Inventors: Shabbir Bambot, Mark L. Faupel, Anant Agrawal, Keith D. Ignotz, Andrew Fordham
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Publication number: 20110306887Abstract: A method and apparatus are provided that interrogate, receive, and analyze full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics. The method includes illuminating a first portion of a target tissue with optical energy, forming a first image of the target tissue, illuminating a second portion of the target tissue with optical energy, performing spectroscopic measurements on optical energy reflected and/or emitted by the target tissue upon illumination of the second portion of the target tissue with optical energy, and determining tissue characteristics of the target tissue based on the results of the spectroscopic measurements.Type: ApplicationFiled: August 22, 2011Publication date: December 15, 2011Applicant: SpectRx, Inc.Inventors: Shabbir Bambot, Mark L. Faupel, Anant Agrawal, Keith D. Ignotz, Andrew Fordham
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Publication number: 20100049078Abstract: Novel methods and apparatus for diagnosing or screening disease states in living organisms by the measurement and analysis of extremely low frequency electromagnetic fields, particularly extremely low frequency alternating current. The measurement of such fields is performed at a single point or at several test points on or in the body and compared to one or more reference. Information in the time-varying electromagnetic field is collected, then processed by diagnostic or screening algorithms to provide information about the disease state of the tissue being assessed.Type: ApplicationFiled: August 13, 2009Publication date: February 25, 2010Inventor: Mark L. FAUPEL
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Publication number: 20080188736Abstract: A method and apparatus are provided that interrogate, receive, and analyze full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics. The method includes illuminating a first portion of a target tissue with optical energy, forming a first image of the target tissue, illuminating a second portion of the target tissue with optical energy, performing spectroscopic measurements on optical energy reflected and/or emitted by the target tissue upon illumination of the second portion of the target tissue with optical energy, and determining tissue characteristics of the target tissue based on the results of the spectroscopic measurements.Type: ApplicationFiled: April 9, 2008Publication date: August 7, 2008Inventors: Shabbir Bambot, Mark L. Faupel, Anant Agrawal, Keith D. Ignotz, Andrew Fordham
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Patent number: 7301629Abstract: An apparatus and method embodying the invention include utilizing a device with a limited number of interrogation devices to accomplish a large number of measurements on a target tissue (50). An instrument embodying the invention includes a plurality of detection devices (54) that are arranged in a predetermined pattern on a tissue contacting face of the instrument. The face of the instrument is located adjacent the target tissue (50), and a plurality of tissue characteristic measurement are simultaneously conducted. The detection devices (54) are moved to a new position, preferably without moving the tissue contacting face, and a second plurality of tissue characteristic measurements are simultaneously conducted. By conducting a series of measurements cycles in this manner, the ultimate resolution of the device is increased, while still obtaining a given resolution, which reduces potential cross-talk errors.Type: GrantFiled: February 9, 2006Date of Patent: November 27, 2007Assignee: SpectRx, Inc.Inventors: Shabbir Bambot, Mark L. Faupel, Glenn Steven Arche
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Patent number: 7041057Abstract: A tissue interface device (10) suitable for positioning on or about one or more artificial openings in a biological membrane of an organism and for coupling to a monitor and control unit and a vacuum source. The tissue interface device (10) comprises a housing (100), a sensor channel (130), and a sensor (150). The housing (100) defines an orifice (120), the orifice (120) having an open inlet port (122) on the bottom end (102) of the housing (100) and a distal end (124) that is in fluid communication with the sensor channel (130). The orifice (120) is in fluid communication with fluid that flows from the artificial opening formed in the biological membranes. The sensor channel (130) is for coupling to, and fluid communication therewith, the vacuum source. The sensor (150) is positioned in the sensor channel (130) in a flow path of the fluid for sensing a characteristic of the fluid as it flows out from the artificial opening. The sensor generates a sensor signal representative thereof.Type: GrantFiled: November 17, 2000Date of Patent: May 9, 2006Assignee: SpectRx, Inc.Inventors: Mark L. Faupel, Krishna Kumar, J. David Farquhar, Mark Vreeke, Alan Smith, Michael Hatch, Teresa Woods
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Patent number: 7006220Abstract: An apparatus and method embodying the invention including utilizing a device with a limited number of interrogation devices to accomplish a large number of measurements on a target tissue. An instrument embodying the invention includes a plurality of detection devices that are arranged in a predetermined pattern on a tissue contacting face of the instrument. The face of the instrument is located adjacent the target tissue, and a plurality of tissue characteristic measurement are simultaneously conducted. The detection devices are moved to a new position, preferably without moving the tissue contacting face, and a second plurality of tissue characteristic measurements are simultaneously conducted. By conducting a series of measurement cycles in this manner, the ultimate resolution of the device is increased, while still obtaining a given resolution, which reduces potential cross-talk errors.Type: GrantFiled: July 3, 2003Date of Patent: February 28, 2006Assignee: SpectRx, Inc.Inventors: Shabbir Bambot, Mark L. Faupel, Glenn Steven Arche
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Patent number: 6975899Abstract: An apparatus and method according to the invention combine more than one optical modality (spectroscopic method), including but not limited to fluorescence, absorption, reflectance, polarization anisotropy, and phase modulation, to decouple morphological and biochemical changes associated with tissue changes due to disease, and thus to provide an accurate diagnosis of the tissue condition.Type: GrantFiled: June 26, 2003Date of Patent: December 13, 2005Assignee: SpectRx, Inc.Inventors: Mark L. Faupel, Shabbir B. Bambot, Tim Harrell, Anant Agrawal
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Patent number: 6870620Abstract: An apparatus embodying the invention includes a probe head with an interrogation surface that is intended to be positioned adjacent or pushed into contact with a target material or tissue. The probe head is constructed to have a plurality of interrogation devices arranged across the face of the interrogation surface. The probe head is also constructed so that the interrogation device can conform to a non-uniform or non-planar surface of the target tissue. In some embodiments, the interrogation surface may have a particular shape that conforms to the shape of a target material. In other embodiments, one or more portions of the interrogation surface could be movable with respect to the remaining portions so that the interrogation surface could be movable with respect to remaining portions so that the interrogation surface can thereby conform to a non-uniform surface. In still other embodiments, a plurality of separately moveable interrogation devices can be arranged across the interrogation surface.Type: GrantFiled: May 29, 2003Date of Patent: March 22, 2005Assignee: Spectrx, Inc.Inventors: Mark L. Faupel, Shabbir B. Bambot, Tim Harrell, J. David Farquhar, Glenn S. Arche, Walter R. Sanders, Edward L. Kimbrell
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Publication number: 20040147843Abstract: A method and apparatus are provided that interrogate, receive, and analyze full emission spectra for at least one fluorescence excitation wavelength and for at least one reflectance measurement to determine tissue characteristics. The method includes illuminating a first portion of a target tissue with optical energy, forming a first image of the target tissue, illuminating a second portion of the target tissue with optical energy, performing spectroscopic measurements on optical energy reflected and/or emitted by the target tissue upon illumination of the second portion of the target tissue with optical energy, and determining tissue characteristics of the target tissue based on the results of the spectroscopic measurements.Type: ApplicationFiled: August 26, 2003Publication date: July 29, 2004Inventors: Shabbir Bambot, Mark L. Faupel, Anant Agrawal, Keith D. Ignotz, Andrew Fordham
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Publication number: 20040119976Abstract: An apparatus embodying the invention includes a probe head with an interrogation surface that is intended to be positioned adjacent or pushed into contact with a target material or tissue. The probe head is constructed to have a plurality of interrogation devices arranged across the face of the interrogation surface. The probe head is also constructed so that the interrogation device can conform to a non-uniform or non-planar surface of the target tissue. In some embodiments, the interrogation surface may have a particular shape that conforms to the shape of a target material. In other embodiments, one or more portions of the interrogation surface could be movable with respect to the remaining portions so that the interrogation surface could be movable with respect to remaining portions so that the interrogation surface can thereby conform to a non-uniform surface. In still other embodiments, a plurality of separately moveable interrogation devices can be arranged across the interrogation surface.Type: ApplicationFiled: May 29, 2003Publication date: June 24, 2004Applicant: SpectRx, Inc.Inventors: Mark L. Faupel, Shabbir B. Bambot, Tim Harrell, J. David Farquhar, Glenn S. Arche, Walter R. Sanders, Edward L. Kimbrell
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Patent number: 6730028Abstract: A method and device for forming artificial openings in a biological membrane with a pyrotechnic charge that is exploded in a controlled manner in proximity of the biological membrane to form the artificial opening(s) therein. The method and device are useful in connection with transdermal delivery and monitoring applications.Type: GrantFiled: October 29, 2001Date of Patent: May 4, 2004Assignee: Altea Therapeutics CorporationInventors: Jonathan A. Eppstein, Michael R. Hatch, Joseph Papp, Mark L. Faupel, Krishna Kumar
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Publication number: 20040021848Abstract: An apparatus and method embodying the invention include utilizing a device with a limited number of interrogation devices to accomplish a large number of measurements on a target tissue (50). An instrument embodying the invention includes a plurality of detection devices (54) that are arranged in a predetermined pattern on a tissue contacting face of the instrument. The face of the instrument is located adjacent the target tissue (50), and a plurality of tissue characteristic measurement are simultaneously conducted. The detection devices (54) are moved to a new position, preferably without moving the tissue contacting face, and a second plurality of tissue characteristic measurements are simultaneously conducted. By conducting a series of measurements cycles in this manner, the ultimate resolution of the device is increased, while still obtaining a given resolution, which reduces potential cross-talk errors.Type: ApplicationFiled: July 3, 2003Publication date: February 5, 2004Applicant: SpectRx, Inc.Inventors: Shabbir Bambot, Mark L. Faupel, Glenn Steven Arche
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Publication number: 20040010197Abstract: An apparatus and method according to the invention combine more than one optical modality (spectroscopic method), including but not limited to fluorescence, absorption, reflectance, polarization anisotropy, and phase modulation, to decouple morphological and biochemical changes associated with tissue changes due to disease, and thus to provide an accurate diagnosis of the tissue condition.Type: ApplicationFiled: June 26, 2003Publication date: January 15, 2004Applicant: SpectRx, IncInventors: Mark L. Faupel, Shabbir B. Bambot, Tim Harrell, Anant Agrawal
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Publication number: 20030135122Abstract: An apparatus and method according to the invention combine more than one optical modality (spectroscopic method), including but not limited to fluorescence, absorption, reflectance, polarization anisotropy, and phase modulation, to decouple morphological and biochemical changes associated with tissue changes due to disease, and thus to provide an accurate diagnosis of the tissue condition.Type: ApplicationFiled: January 8, 2003Publication date: July 17, 2003Applicant: SpectRx, Inc.Inventors: Shabbir B. Bambot, Mark L. Faupel, Tim Harrell, Anant Agrawal
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Patent number: 6590651Abstract: An apparatus and method embodying the invention include utilizing a device with a limited number of interrogation devices to accomplish a large number of measurements on a target tissue (50). An instrument embodying the invention includes a plurality of detection devices (54) that are arranged in a predetermined pattern on a tissue contacting face of the instrument. The face of the instrument is located adjacent the target tissue (50), and a plurality of tissue characteristic measurement are simultaneously conducted. The detection devices (54) are moved to a new position, preferably without moving the tissue contacting face, and a second plurality of tissue characteristic measurements are simultaneously conducted. By conducting a series of measurements cycles in this manner, the ultimate resolution of the device is increased, while still obtaining a given resolution, which reduces potential cross-talk errors.Type: GrantFiled: November 16, 2000Date of Patent: July 8, 2003Assignee: SpectRx, Inc.Inventors: Shabbir Bambot, Mark L. Faupel, Glenn Steven Arche
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Patent number: 6577391Abstract: An apparatus embodying the invention includes a probe head with an interrogation surface that is intended to be positioned adjacent or pushed into contact with a target material or tissue. The probe head is constructed to have a plurality of interrogation devices arranged across the face of the interrogation surface. The probe head is also constructed so that the interrogation device can conform to a non-uniform or non-planar surface of the target tissue. In some embodiments, the interrogation surface may have a particular shape that conforms to the shape of a target material. In other embodiments, one or more portions of the interrogation surface could be movable with respect to the remaining portions so that the interrogation surface could be movable with respect to remaining portions so that the interrogation surface can the thereby conform to a non-uniform surface. In still other embodiments, a plurality of separately moveable interrogation devices can be arranged across the interrogation surface.Type: GrantFiled: March 24, 2000Date of Patent: June 10, 2003Assignee: SpectRx, Inc.Inventors: Mark L. Faupel, Shabbir B. Bambot, Tim Harrell, J. David Farquhar, Glenn S. Arche, Walter R. Sanders, Edward L. Kimbrell
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Publication number: 20020091311Abstract: A method and device for forming artificial openings in a biological membrane with a pyrotechnic charge that is exploded in a controlled manner in proximity of the biological membrane to form the artificial opening(s) therein. The method and device are useful in connection with transdermal delivery and monitoring applications.Type: ApplicationFiled: October 29, 2001Publication date: July 11, 2002Inventors: Jonathan A. Eppstein, Michael R. Hatch, Joseph Papp, Mark L. Faupel, Krishna Kumar