Abstract: Medical devices and systems for treating a stricture, for example along the biliary and/or pancreatic tract, are disclosed. An example system may include a guidewire having a distal end and defining a lumen. A stiffening rod may be slidably disposed within the lumen. The stiffening rod may have a distal end and a distal end region disposed adjacent to the distal end. The stiffening rod may be configured to shift between a first position where the distal end of the stiffening rod is disposed proximally of the distal end of the guidewire and a second position where the distal end of the stiffening rod is disposed distally of the distal end of the guidewire.

Abstract: A method may comprise: receiving, via a controller and through a camera, visual data corresponding to a row of latch assemblies in a cargo handling system; and determining, via the controller, whether each latch assembly in the row of latch assemblies is in a properly securing state.

Abstract: A restraint assembly includes a base configured to be mounted to a tray of the cargo system, a lateral restraint, and a vertical restraint. The lateral restraint comprises a guide face and a top edge, wherein the lateral restraint is rotatably coupled to the base, according to various embodiments. The vertical restraint extends from the top edge of the lateral restraint, according to various embodiments. The restraint assembly comprises a stored position and a raised position. In the stored position both the lateral restraint and the vertical restraint are configured to be disposed within a volume defined by the tray of the cargo system. In the raised position the vertical restraint and at least the guide face of the lateral restraint are configured to be disposed above the volume defined by the tray of the cargo system to provide guidance and restraint to cargo.

Abstract: A restraint assembly includes a lateral restraint comprising a guide face, wherein the lateral restraint is configured to be rotatably coupled to a tray of the cargo system. The restraint assembly also includes a vertical restraint rotatably coupled to the lateral restraint. The restraint assembly is configured to have a stored position and a raised position. In the stored position, both the lateral restraint and the vertical restraint are configured to be disposed within a volume defined by the tray of the cargo system. In the raised position, the vertical restraint and at least the guide face of the lateral restraint are configured to be disposed above the volume defined by the tray of the cargo system such that the restraint assembly provides at least one of longitudinal guidance, lateral restraint, and vertical restraint to cargo.

Abstract: A restraint assembly includes a lateral restraint comprising a guide face, wherein the lateral restraint is configured to be rotatably coupled to a tray of the cargo system. The restraint assembly also includes a vertical restraint rotatably coupled to the lateral restraint. The restraint assembly is configured to have a stored position and a raised position. In the stored position, both the lateral restraint and the vertical restraint are configured to be disposed within a volume defined by the tray of the cargo system. In the raised position, the vertical restraint and at least the guide face of the lateral restraint are configured to be disposed above the volume defined by the tray of the cargo system such that the restraint assembly provides at least one of longitudinal guidance, lateral restraint, and vertical restraint to cargo.

Abstract: A restraint assembly includes a base configured to be mounted to a tray of the cargo system, a lateral restraint, and a vertical restraint. The lateral restraint comprises a guide face and a top edge, wherein the lateral restraint is rotatably coupled to the base, according to various embodiments. The vertical restraint extends from the top edge of the lateral restraint, according to various embodiments. The restraint assembly comprises a stored position and a raised position. In the stored position both the lateral restraint and the vertical restraint are configured to be disposed within a volume defined by the tray of the cargo system. In the raised position the vertical restraint and at least the guide face of the lateral restraint are configured to be disposed above the volume defined by the tray of the cargo system to provide guidance and restraint to cargo.

Abstract: A tray mounted lateral guide for use between trays of a cargo bay having a bay floor includes a main body defining a roller slot. The tray mounted lateral guide further includes a roller configured to be at least partially positioned in the roller slot and to facilitate conveyance of a pallet through the cargo bay. The tray mounted lateral guide further includes a lifter coupled to the main body and configured to be coupled to a tray and to maintain the main body in at least one of a lowered position or a raised position, the main body being further from the bay floor when in the raised position than when in the lowered position.

Abstract: A tray mounted lateral guide for use between trays of a cargo bay having a bay floor includes a main body defining a roller slot. The tray mounted lateral guide further includes a roller configured to be at least partially positioned in the roller slot and to facilitate conveyance of a pallet through the cargo bay.

Abstract: A cargo handling system for restraining a unit load device includes a structural channel having a hollow interior and at least one roller rotatably mounted within said hollow interior. At least one locking mechanism associated with said structural channel is movable to engage the unit load device. At least one side roller assembly is operably coupled to an exterior surface of said structural channel. The at least one side roller assembly includes a side roller positioned such that said an upper surface of said at least one roller and an upper surface of said side roller are disposed within a plane for supporting said unit load device.

Abstract: Systems, methods, and apparatus are provided that allow a user to draw and edit a chemical structure. Aspects of the present disclosure may include receiving an input corresponding to an amendment to a portion of an in-progress chemical structure, and identifying, based at least in part upon the amended in-progress chemical structure, one or more molecular scaffolds from a set of candidate molecular scaffolds. Each molecular scaffold may be configured to, upon one or both of (i) appending to the amended portion of the in-progress chemical structure and (ii) replacing or partially replacing the amended portion of the in-progress chemical structure, provide a resulting chemical structure or chemical structure fragment that has been previously rendered. The one or more molecular scaffolds may be provided for presentation on the graphical display as option(s) for selection by a user in creating the graphical representation of the chemical structure.

Abstract: Systems, methods, and apparatus are provided that allow a user to draw and edit a chemical structure. Aspects of the present disclosure may include receiving an input corresponding to an amendment to a portion of an in-progress chemical structure, and identifying, based at least in part upon the amended in-progress chemical structure, one or more molecular scaffolds from a set of candidate molecular scaffolds. Each molecular scaffold may be configured to, upon one or both of (i) appending to the amended portion of the in-progress chemical structure and (ii) replacing or partially replacing the amended portion of the in-progress chemical structure, provide a resulting chemical structure or chemical structure fragment that has been previously rendered. The one or more molecular scaffolds may be provided for presentation on the graphical display as option(s) for selection by a user in creating the graphical representation of the chemical structure.

Abstract: A method for graphically forming a difference spectrum from a sample spectrum and a reference spectrum on a computer system includes displaying an initial difference spectrum on the display the initial difference spectrum being equal to the sample spectrum, selecting a data point in the initial difference spectrum, having an associated wave number, with a relative pointing device on the display, moving the data point a measurable amount on the display with the relative pointing device, determining a scaling factor in response to the measurable amount and to a data point in the reference spectrum having the same associated wave number, scaling each data point in the reference spectrum by the scaling factor to form a scaled reference spectrum, determining the difference spectrum between the sample spectrum and the scaled reference spectrum, and displaying at least a portion of the difference spectrum on the display.

Abstract: A method for graphically forming a difference spectrum from a sample spectrum and a reference spectrum on a computer system includes displaying an initial difference spectrum on the display the initial difference spectrum being equal to the sample spectrum, selecting a data point in the initial difference spectrum, having an associated wave number, with a relative pointing device on the display, moving the data point a measurable amount on the display with the relative pointing device, determining a scaling factor in response to the measurable amount and to a data point in the reference spectrum having the same associated wave number, scaling each data point in the reference spectrum by the scaling factor to form a scaled reference spectrum, determining the difference spectrum between the sample spectrum and the scaled reference spectrum, and displaying at least a portion of the difference spectrum on the display.

Abstract: A method for graphically forming a difference spectrum from a sample spectrum and a reference spectrum on a computer system includes displaying an initial difference spectrum on the display the initial difference spectrum being equal to the sample spectrum, selecting a data point in the initial difference spectrum, having an associated wave number, with a relative pointing device on the display, moving the data point a measurable amount on the display with the relative pointing device, determining a scaling factor in response to the measurable amount and to a data point in the reference spectrum having the same associated wave number, scaling each data point in the reference spectrum by the scaling factor to form a scaled reference spectrum, determining the difference spectrum between the sample spectrum and the scaled reference spectrum, and displaying at least a portion of the difference spectrum on the display.