Patents by Inventor Mark L. Spano

Mark L. Spano has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • System behavior modification for maintenance of chaos
    Patent number: 6606526
    Abstract: An accessible parameter of a chaos embodying system of a physical or biological type is monitored by extraction of measurement data and recordation thereof on a return map as a dynamic representation of the system activity, from which the magnitude and timing of intervention is determined and applied to the system in order to sustain chaos behavior.
    Type: Grant
    Filed: September 26, 2001
    Date of Patent: August 12, 2003
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Mark L. Spano, William L. Ditto, Visarath In
  • Electric field control of epiletiform activity
    Patent number: 5800459
    Abstract: A DC electric field is applied to brain tissue in parallel alignment with urons thereof during periods of brief duration while the tissue is undergoing epileptic activity. The electric field is controllably changed in polarity and magnitude to modify such epileptic activity based on data obtained by recording such activity through electrodes that are isopotentially aligned within the electric field imposed on a slice of the brain tissue.
    Type: Grant
    Filed: December 24, 1996
    Date of Patent: September 1, 1998
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Mark L. Spano, Steven J. Schiff, Bruce J. Gluckman, William L. Ditto
  • Suppression of epileptiform activity
    Patent number: 5797965
    Abstract: A DC electric field is applied to brain tissue in parallel alignment with urons thereof during periods of brief duration while the tissue is undergoing epileptic activity. The electrical field is controllably varied in magnitude to suppress such epilieptic activity.
    Type: Grant
    Filed: March 26, 1997
    Date of Patent: August 25, 1998
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Mark L. Spano, Steven J. Schiff, Bruce J. Gluckman, William L. Ditto
  • Pulsating behavior monitoring and modification system for neural networks
    Patent number: 5522863
    Abstract: The pulsating behavioral activity of a neural network such as that embodied n a brain tissue slice is monitored by measurement of intervals between spontaneous events to identify the presence of a chaotic regime and determine by real-time calculation a waiting time for electrical pulse intervention pursuant to a behavioral modifying program having a control or anti-control strategy.
    Type: Grant
    Filed: August 19, 1994
    Date of Patent: June 4, 1996
    Assignee: The United States of America as represented by the Secretary of the Navy
    Inventors: Mark L. Spano, William L. Ditto, Steven J. Schiff
  • Real time stabilizing system for pulsating activity
    Patent number: 5447520
    Abstract: Electrical stimuli delivered to cardiac tissue at times determined from a chaos stabilizing algorithm, converts arrhythmia activity to periodic beating by an interbeat interval shortening action, utilizing real time calculation based on a system parameter experimentally determined from intervention by the electrical stimuli.
    Type: Grant
    Filed: March 29, 1994
    Date of Patent: September 5, 1995
    Assignee: The Regents of the University of California
    Inventors: Mark L. Spano, William L. Ditto, Alan Garfinkel, James N. Weiss
  • Real time cardiac arrhythmia stabilizing system
    Patent number: 5342401
    Abstract: Electrical stimuli delivered to cardiac tissue at times determined from a chaos stabilizing algorithm, converts arrhythmia activity to periodic beating by an interbeat interval shortening action, utilizing real time calculation based on a system parameter experimentally determined from intervention by the electrical stimuli.
    Type: Grant
    Filed: August 19, 1992
    Date of Patent: August 30, 1994
    Assignee: The Regents of the University of California
    Inventors: Mark L. Spano, William L. Ditto, Alan Garfinkel, James N. Weiss