Abstract: Provided for may be a pump failsafe apparatus for use with a pump motor, the pump failsafe apparatus comprising a foot pedal configured to generate a first signal when depressed and a second signal when released. The apparatus may comprise a power supply having an internal logic controlled power switch, the power supply in electrical communication with at least the pump motor, wherein the internal logic controlled power switch includes an active state (ON) and an inactive state (OFF). The apparatus may further include an overspeed detector, an under voltage detector in electrical communication with at least the power supply, the under voltage detector configured to measure a logic voltage, and a pump cartridge detector.

Abstract: A bioadhesive nanoparticle (BNP) for long-lasting local drug delivery to treat cancer was developed. The bioadhesive nanoparticles (BNP) are composed of biodegradable polymer such as poly(lactic acid)-hyperbranched polyglycerol (PLA-HPG), encapsulating a chemotherapeutic such as camptothecin (CPT). Nanoparticles (NPs) of PLA-HPG are non-adhesive NPs (NNPs), which are stealthy in their native state, but conversion of the vicinal diols of HPG to aldehydes confers the ability to form strong covalent bonds with amine-rich surfaces. The formulation is administered in combination with immunostimulatory molecules such as CPG and shows unexpectedly better killing of cancer cells.

Abstract: A method for notifying and mitigating a suboptimal event occurring in a transport climate control system that provides climate control to a climate controlled space of a transport unit is provided. The method includes monitoring an amount of power available for powering the transport climate control system, monitoring a power demand from the transport climate control system, and accessing operational data of the transport climate control system and the transport unit. The method also includes a controller determining whether a suboptimal event is detected based on one or more of the monitored amount of power available, the monitored power demand and the accessed operational data. Also, the method includes the controller generating a notification when a suboptimal event is detected, and the controller instructing the generated notification to be displayed on a display.

Abstract: Provided herein are compositions comprising a composite of peptide amphiphile nanofibers and hyaluronic acid (HA) particles, and methods of preparation and use thereof, such as for repair of a cartilage or osteochondral defects.

Abstract: The present disclosure is directed to an apparatus and method for processing lignocellulosic material. The apparatus includes a vessel having a fluid separation plate disposed therein, a fluid circulating system in fluid communication with the vessel and various component parts including nozzles, valves, lines and pumps as needed for discharging processed lignocellulosic materials.

Abstract: A method implemented by a memory controller may comprise receiving segment pointers that identify memory devices and slices for associated segments. The method may comprise identifying a most-full first one of the memory devices. The method may comprise identifying a most-empty second one of the memory devices. The method may comprise identifying one of the segments in the most-full one of the memory devices. The method may comprise moving a slice from the identified one of the segments in the most-full one of the memory devices to the most-empty one of the memory devices. The method may comprise updating one of the segment pointers for the identified segment.

Abstract: A connector assembly includes a base and a detachable cover. Ports on separate sidewalls receive an extension cable and a lead. A blade assembly maintains electrical contact between the cable and the lead, while providing a surface to strip insulation and/or sever the lead. Further, the blade is resilient so as to maintain sufficient contact with the lead when the cover is attached and/or locked to the base.

Abstract: Systems and methods are provided for providing energy consumption feedback for powering a transport climate control system using external data. This can include determining whether an energy level of an energy storage source is greater than an expected energy consumption of a transport climate control system during a route, based on route parameters and route conditions. The route conditions may be obtained from a source such as a remote server, and include data such as weather data, traffic data, or the like. The systems and methods may further compare current energy levels to an updated predictions of energy consumption during transit to determine if the energy level is sufficient to complete the route and alert the user when the energy level is insufficient to complete the route.

Abstract: A portable, self-contained beverage apparatus includes a container assembly having a known storage capacity for storing a consumable liquid, and a dispensing assembly disposed within the container assembly that dispenses variable, non-zero quantities of additives into the consumable liquid. The dispensing assembly includes multiple apertures structured and arranged to retain vessels containing the additives to be dispensed into the consumable liquid. The beverage apparatus also includes a level sensor disposed within the container assembly that determines a consumable liquid level of the consumable liquid stored in the container assembly. In certain embodiments, one or more positive displacement pumping mechanisms are configured to pump additive liquid from additive containers into a beverage chamber.

Abstract: A computer-implemented method includes a machine learning system receiving distinct types of data associated with multiple individual entities. For each of the individual entities, the machine learning system determines a first attribute that indicates a predicted attribute of the entity based on analysis of the data. The machine learning system also determines a second attribute that indicates a predicted quality attribute of the entity, based on analysis of the data. An attribute weighting module of the machine learning system generates weight values for each of the first attribute and the second attribute of the entity. The machine learning system generates a data structure that identifies a set of entities from among the multiple individual entities, where entities of the set are ranked based on a tier indicator that corresponds to either the first attribute, the second attribute, or both.

Abstract: Systems and methods are provided for providing predictive energy consumption feedback for powering a transport climate control system. This can include determining whether an energy level of an energy storage source is greater than an expected energy consumption of a transport climate control system during a route, based on route parameters. The route parameters may be obtained via a human-machine interface. When the energy storage source is less than the expected energy consumption, a user is alerted. The systems and methods may further compare the energy level to an expected energy level during transit to determine if the energy level is greater or less than expected and alert the user when the energy level is less than expected.

Abstract: Provided for may be a motor speed control apparatus for use with a piston pump. The piston may be adapted to create a plurality of compressions and the piston may have a compression path and a decompression path. Further, the piston cylinder may include a proximal end, a distal end, and a piston length. The piston cylinder may have a proximal threshold position and a distal threshold position. In an embodiment, the apparatus includes a proximal and a distal hall effect sensor. The apparatus may comprise a computer, wherein instructions instruct the piston to decelerate at the distal threshold position during the compression path and the proximal threshold position during the decompression path, and/or wherein the computer executable instructions instruct the piston to accelerate at the distal threshold position during the decompression path and the proximal threshold position during the compression path.

Abstract: A blow molded article obtained by blow molding of a preform made via parallel flow coinjection, having a wall formed by 3 layers in at least a region wherein the outside layer is transparent and the inner layer comprises an effect pigment visible through the transparent layer. Articles according to the invention have an improved gloss, low haze and higher resistance to delamination than previous articles. The invention relates also to preforms for making articles as described and to methods for making preforms and articles.

Abstract: A method for notifying and mitigating a suboptimal event occurring in a transport climate control system that provides climate control to a climate controlled space of a transport unit is provided. The method includes monitoring an amount of power available for powering the transport climate control system, monitoring a power demand from the transport climate control system, and accessing operational data of the transport climate control system and the transport unit. The method also includes a controller determining whether a suboptimal event is detected based on one or more of the monitored amount of power available, the monitored power demand and the accessed operational data. Also, the method includes the controller generating a notification when a suboptimal event is detected, and the controller instructing the generated notification to be displayed on a display.

Abstract: Methods and apparatuses for sequencing by synthesis using mechanical compression. These methods and apparatuses may mechanically control microfluidic movement using a force applicator and an elastically deformable sheet.

Abstract: A group head (20) for an espresso machine (10), the group head (20) comprising: a group head bracket (36) for detachable engagement with a portafilter (30) holding a puck (22) of ground coffee in a filter basket (64) to dispense an espresso coffee; a conduit (34) for receiving a flow of water to the portafilter (30); and, a heater (32) mounted in the group head (20) to heat the flow of water to the portafilter (30).

Abstract: Provided is an electromagnetic interference mitigation apparatus including a power supply; a power cord; a power supply chassis encapsulating at least the power supply, the power supply physically isolated from the power cord; a low value resistor in electrical communication with at least the power cord and the power supply; and a capacitor disposed between the power supply chassis and an equipment chassis, wherein the equipment chassis encapsulates the power supply chassis, wherein the equipment chassis is disposed a distance from the power supply chassis, and wherein the capacitor is formed by the equipment chassis and the power supply chassis.

Abstract: Methods and apparatuses for mechanically controlling microfluidic movement using a force applicator and an elastically deformable sheet are described herein. These apparatuses may include a mechanical microfluidics actuator devices and a cartridge. A microfluidic droplet may be moved or displaced within an air gap of the cartridge by applying a compressive force locally and selectively reduce the gap width of the air gap near the microfluidic droplet causing the microfluidic droplet to move toward the reduced gap. Compressive forces may also be used to divide, join, mix or perform other operations on the microfluidic droplets.

Abstract: An integrated circuit includes conversion circuitry for converting first data in a first data format optimized for efficient data storage into second data in a second data format optimized for processing by a processing circuit. The integrated circuit also includes filter circuitry for filtering the second data to generate filtered data in the second data format. The integrated circuit outputs the filtered data for processing by the processing circuit.