Patents by Inventor Mark M. Dehdashtian

Mark M. Dehdashtian has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11446139
    Abstract: A collapsible device, such as an annuloplasty ring or prosthetic heart valve, is configured to be collapsed prior to being introduced into a patient via minimally-invasive access points such as port holes or intercostal incisions. A holder is configured to hold the collapsible device, and to selectively collapse the device for introduction into the patient and then re-enlarge the device at the desired deployment site. Collapsible devices include devices that can hingedly fold about hinge lines, and devices that can elongate to form substantially spiral forms with reduced diameters.
    Type: Grant
    Filed: December 23, 2019
    Date of Patent: September 20, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Teodoro S. Jimenez, Mark M. Dehdashtian, Raffaele Mazzei
  • Publication number: 20220183835
    Abstract: A method of delivering a prosthetic heart valve to the aortic valve annulus while a patient's heart is beating is disclosed. The method includes accessing the left ventricle through an intercostal incision and forming a puncture in the left ventricle. A guidewire is advanced into the left ventricle and through the native aortic valve. An introducer is passed over the guidewire and into the left ventricle. A valve delivery device is advanced over the guidewire and through the introducer until a prosthetic heart valve positioned thereon is located within the native aortic valve. The prosthetic heart valve is then radially expanded within the aortic valve annulus for replacing the function of the native aortic valve.
    Type: Application
    Filed: March 3, 2022
    Publication date: June 16, 2022
    Applicant: Edwards Lifesciences Corporation
    Inventors: Mark M. Dehdashtian, Jane M. Olin
  • Patent number: 11291542
    Abstract: Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.
    Type: Grant
    Filed: August 23, 2019
    Date of Patent: April 5, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Walter Lee, Mark M. Dehdashtian, Teodoro S. Jimenez, Gilbert S. Leung, Bryan A. Janish, Michael G. Valdez, Tram Ngoc Nguyen, Timothy C. Ulrich
  • Patent number: 11266500
    Abstract: A method of delivering a prosthetic heart valve to the aortic valve annulus while a patient's heart is beating is disclosed. The method includes accessing the left ventricle through an intercostal incision and forming a puncture in the left ventricle. A guidewire is advanced into the left ventricle and through the native aortic valve. An introducer is passed over the guidewire and into the left ventricle. A valve delivery device is advanced over the guidewire and through the introducer until a prosthetic heart valve positioned thereon is located within the native aortic valve. The prosthetic heart valve is then radially expanded within the aortic valve annulus for replacing the function of the native aortic valve.
    Type: Grant
    Filed: June 11, 2019
    Date of Patent: March 8, 2022
    Assignee: Edwards Lifesciences Corporation
    Inventors: Mark M. Dehdashtian, Jane M. Olin
  • Publication number: 20200289123
    Abstract: Aortic occlusion and embolic protection devices include radially expandable and collapsible proximal and distal end portions, such as annular self-expanding stents or frames, that are configured to radially expand within an aorta to secure the device within the aorta. The devices can also include a catheter extending axially between the distal end portion and the proximal end portion and a porous covering, or filter, positioned around the catheter and between the proximal end portion and the distal end portion and configured to filter emboli from blood flowing into upper-body arteries. The device can further include a one-way valve positioned at or adjacent to the distal end portion of the device and configured to restrict retrograde blood flow through the device toward the heart.
    Type: Application
    Filed: May 28, 2020
    Publication date: September 17, 2020
    Inventors: Mark M. Dehdashtian, Teodoro S. Jimenez, Nathan Satter, Fabian Daniel Schroeder, Raffaele Mazzei, Jeff Kosmoski, Shahram Zamani, Adam J. Yestrepsky
  • Patent number: 10751522
    Abstract: A bi-directional cannula for perfusing blood in two directions. The cannula has a distal opening in fluid communication with a cannula first lumen. The cannula has a secondary opening proximal of the distal opening, and may include a movable tubular extension selectively extendable from the cannula via the secondary opening. The tubular extension may be in fluid connection with the cannula first lumen and/or a cannula second lumen. The tubular extension may have distal and/or side openings, with the openings providing antegrade fluid perfusion. The cannula second lumen may be separate from the first lumen, so that perfusion can be selectively provided to just the cannula distal opening, just the secondary opening/tubular extension, or simultaneously to both the distal opening and secondary opening/tubular extension.
    Type: Grant
    Filed: May 29, 2018
    Date of Patent: August 25, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Thomas Walther, Mark M. Dehdashtian, Teodoro S. Jimenez, Norma A. Garcia
  • Publication number: 20200229921
    Abstract: Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.
    Type: Application
    Filed: April 6, 2020
    Publication date: July 23, 2020
    Inventors: Walter Lee, Mark M. Dehdashtian, Teodoro S. Jimenez, Gilbert S. Leung, Bryan A. Janish, Michael G. Valdez, Tram Ngoc Nguyen, Timothy C. Ulrich
  • Patent number: 10667821
    Abstract: Embodiments of aortic occlusion devices are described herein that include radially expandable and collapsible proximal and distal end portions, such as annular self-expanding stents or frames, that are configured to radially expand within an aorta to secure the device within the aorta. The devices can also include a catheter extending axially between the distal end portion and the proximal end portion and a porous covering, or filter, positioned around the catheter and between the proximal end portion and the distal end portion and configured to filter emboli from blood flowing into upper-body arteries. The device can further include a one-way valve positioned at or adjacent to the distal end portion of the device and configured to restrict retrograde blood flow through the device toward the heart.
    Type: Grant
    Filed: November 16, 2018
    Date of Patent: June 2, 2020
    Assignee: Edwards Lifesciences Corporation
    Inventors: Mark M. Dehdashtian, Teodoro S. Jimenez, Nathan Satter, Fabian Daniel Schroeder, Raffaele Mazzei, Jeff Kosmoski, Shahram Zamani, Adam J. Yestrepsky
  • Publication number: 20200129289
    Abstract: A collapsible device, such as an annuloplasty ring or prosthetic heart valve, is configured to be collapsed prior to being introduced into a patient via minimally-invasive access points such as port holes or intercostal incisions. A holder is configured to hold the collapsible device, and to selectively collapse the device for introduction into the patient and then re-enlarge the device at the desired deployment site. Collapsible devices include devices that can hingedly fold about hinge lines, and devices that can elongate to form substantially spiral forms with reduced diameters.
    Type: Application
    Filed: December 23, 2019
    Publication date: April 30, 2020
    Inventors: Teodoro S. Jimenez, Mark M. Dehdashtian, Raffaele Mazzei
  • Publication number: 20200100896
    Abstract: A delivery system and method for delivering a prosthetic heart valve to the aortic valve. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic valve through an introducer passing into the left ventricle through its apex. The introducer may have a more floppy distal section than a proximal section to reduce trauma to the heart wall while preserving good operating field stability. The delivery catheter includes a deflecting segment just proximal to a distal balloon to facilitate positioning of the prosthetic heart valve in the proper orientation. A trigger in a catheter handle may be coupled to a deflection wire that actuates the deflecting segment, while a slider in the handle controls retraction of a valve pusher. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.
    Type: Application
    Filed: December 4, 2019
    Publication date: April 2, 2020
    Inventors: Teodoro S. Jimenez, Walter Lee, Mark M. Dehdashtian, Kristopher J. Yee
  • Patent number: 10512536
    Abstract: A collapsible device, such as an annuloplasty ring or prosthetic heart valve, is configured to be collapsed prior to being introduced into a patient via minimally-invasive access points such as port holes or intercostal incisions. A holder is configured to hold the collapsible device, and to selectively collapse the device for introduction into the patient and then re-enlarge the device at the desired deployment site. Collapsible devices include devices that can hingedly fold about hinge lines, and devices that can elongate to form substantially spiral forms with reduced diameters.
    Type: Grant
    Filed: October 26, 2017
    Date of Patent: December 24, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Teodoro S. Jimenez, Mark M. Dehdashtian, Raffaele Mazzei
  • Publication number: 20190374341
    Abstract: Described herein are systems and methods from delivering prosthetic devices, such as prosthetic heart valves, through the body and into the heart for implantation therein. The prosthetic devices delivered with the delivery systems disclosed herein are, for example, radially expandable from a radially compressed state mounted on the delivery system to a radially expanded state for implantation using an inflatable balloon of the delivery system. Exemplary delivery routes through the body and into the heart include transfemoral routes, transapical routes, and transaortic routes, among others.
    Type: Application
    Filed: August 23, 2019
    Publication date: December 12, 2019
    Inventors: Walter Lee, Mark M. Dehdashtian, Teodoro S. Jimenez, Gilbert S. Leung, Bryan A. Janish, Michael G. Valdez, Tram Ngoc Nguyen, Timothy C. Ulrich
  • Patent number: 10500044
    Abstract: A delivery system and method for delivering a prosthetic heart valve to the aortic valve. The system includes a delivery catheter having a steering mechanism thereon for delivering a balloon-expandable prosthetic heart valve to the aortic valve through an introducer passing into the left ventricle through its apex. The introducer may have a more floppy distal section than a proximal section to reduce trauma to the heart wall while preserving good operating field stability. The delivery catheter includes a deflecting segment just proximal to a distal balloon to facilitate positioning of the prosthetic heart valve in the proper orientation. A trigger in a catheter handle may be coupled to a deflection wire that actuates the deflecting segment, while a slider in the handle controls retraction of a valve pusher. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.
    Type: Grant
    Filed: July 27, 2017
    Date of Patent: December 10, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Teodoro S. Jimenez, Walter Lee, Mark M. Dehdashtian, Kristopher J. Yee
  • Publication number: 20190290425
    Abstract: A method of delivering a prosthetic heart valve to the aortic valve annulus while a patient's heart is beating is disclosed. The method includes accessing the left ventricle through an intercostal incision and forming a puncture in the left ventricle. A guidewire is advanced into the left ventricle and through the native aortic valve. An introducer is passed over the guidewire and into the left ventricle. A valve delivery device is advanced over the guidewire and through the introducer until a prosthetic heart valve positioned thereon is located within the native aortic valve. The prosthetic heart valve is then radially expanded within the aortic valve annulus for replacing the function of the native aortic valve.
    Type: Application
    Filed: June 11, 2019
    Publication date: September 26, 2019
    Inventors: Mark M. Dehdashtian, Jane M. Olin
  • Patent number: 10314702
    Abstract: A method of delivering a prosthetic heart valve to the aortic valve annulus while a patient's heart is beating is disclosed. The method includes accessing the left ventricle through an intercostal incision and forming a puncture in the left ventricle. A guidewire is advanced into the left ventricle and through the aortic valve. An introducer is passed over the guidewire and into the left ventricle. A valve delivery device is advanced over the guidewire and through the introducer until a prosthetic heart valve positioned thereon is located within the aortic valve. The prosthetic heart valve is then radially expanded within the aortic valve annulus for replacing the function of the native aortic valve.
    Type: Grant
    Filed: May 16, 2017
    Date of Patent: June 11, 2019
    Assignee: Edwards Lifesciences Corporation
    Inventors: Mark M. Dehdashtian, Jane M. Olin
  • Publication number: 20190083102
    Abstract: Embodiments of aortic occlusion devices are described herein that include radially expandable and collapsible proximal and distal end portions, such as annular self-expanding stents or frames, that are configured to radially expand within an aorta to secure the device within the aorta. The devices can also include a catheter extending axially between the distal end portion and the proximal end portion and a porous covering, or filter, positioned around the catheter and between the proximal end portion and the distal end portion and configured to filter emboli from blood flowing into upper-body arteries. The device can further include a one-way valve positioned at or adjacent to the distal end portion of the device and configured to restrict retrograde blood flow through the device toward the heart.
    Type: Application
    Filed: November 16, 2018
    Publication date: March 21, 2019
    Inventors: Mark M. Dehdashtian, Jorge H. Jimenez, Nathan Satter, Fabian Daniel Schroeder, Raffaele Mazzei, Jeff Kosmoski, Shahram Zamani, Adam J. Yestrepsky
  • Publication number: 20190070000
    Abstract: A delivery system and method for delivering a prosthetic heart valve to the aortic valve annulus via a transaortic approach. The system includes a balloon catheter for delivering a balloon-expandable prosthetic heart valve through an introducer from an approach from outside the patient, through a minimally-invasive opening in the chest cavity through an incision in the aorta, and into the aorta and aortic annulus. The balloon catheter includes a flexible, tapered tip just distal of the balloon to facilitate positioning of the prosthetic heart valve in the proper orientation within the aortic annulus. The prosthetic heart valve may be installed over the existing calcified leaflets, and a pre-dilation valvuloplasty procedure may also be utilized.
    Type: Application
    Filed: November 1, 2018
    Publication date: March 7, 2019
    Inventors: Mark M. Dehdashtian, Teodoro S. Jimenez
  • Publication number: 20180280017
    Abstract: A device is described that has an instrument portion secured to a sleeve/cuff portion, where the sleeve/cuff portion is configured to receive a portion of user's finger therein and to radially compress onto the user's finger to hold the instrument portion thereon. The present invention is particularly well suited for use in minimally invasive surgical procedures. The present invention also teaches a method of forming a knot in suture material as well as other techniques for treating patients.
    Type: Application
    Filed: June 7, 2018
    Publication date: October 4, 2018
    Inventors: L'Emir Ahmad El-Ayoubi, Mark M. Dehdashtian, Teodoro S. Jimenez, Yoon H. Kwon, Norma A. Garcia
  • Publication number: 20180272116
    Abstract: A bi-directional cannula for perfusing blood in two directions. The cannula has a distal opening in fluid communication with a cannula first lumen. The cannula has a secondary opening proximal of the distal opening, and may include a movable tubular extension selectively extendable from the cannula via the secondary opening. The tubular extension may be in fluid connection with the cannula first lumen and/or a cannula second lumen. The tubular extension may have distal and/or side openings, with the openings providing antegrade fluid perfusion. The cannula second lumen may be separate from the first lumen, so that perfusion can be selectively provided to just the cannula distal opening, just the secondary opening/tubular extension, or simultaneously to both the distal opening and secondary opening/tubular extension.
    Type: Application
    Filed: May 29, 2018
    Publication date: September 27, 2018
    Inventors: Thomas Walther, Mark M. Dehdashtian, Teodoro S. Jimenez, Norma A. Garcia
  • Publication number: 20180042722
    Abstract: A collapsible device, such as an annuloplasty ring or prosthetic heart valve, is configured to be collapsed prior to being introduced into a patient via minimally-invasive access points such as port holes or intercostal incisions. A holder is configured to hold the collapsible device, and to selectively collapse the device for introduction into the patient and then re-enlarge the device at the desired deployment site. Collapsible devices include devices that can hingedly fold about hinge lines, and devices that can elongate to form substantially spiral forms with reduced diameters.
    Type: Application
    Filed: October 26, 2017
    Publication date: February 15, 2018
    Inventors: Teodoro S. Jimenez, Mark M. Dehdashtian, Raffaele Mazzei