Abstract: The present invention is directed to the method and apparatus for the robotic harvesting of solids from liquids as exemplified by harvesting protein crystals. Further, the present invention is directed to a fluid/solid management system in a chamber that automates the task of solid harvesting. The fluid/solid management system includes two supporting structures for at least one pipette on one structure and a second pipette on the other structure, the two pipettes in tip-to-tip alignment. The pipettes each having a drop of liquid at the end thereof are moved apart to form a liquid bridge in which the solid crystal is isolated. A robotic arm has a device on the end thereof for the harvesting of the solid at the working point between the tips of the pipettes. The system has a flash freezing system in the chamber for the safe storage of the harvested solid.