Patents by Inventor Mark Ma

Mark Ma has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12590977
    Abstract: Provided herein are antibodies which bind to ceruloplasmin and are useful for various applications, including detecting ceruloplasmin and immunocapturing ceruloplasmin in biological samples. The antibodies are useful in methods of measuring non-ceruloplasmin-bound copper concentrations and labile-bound copper concentrations in biological samples.
    Type: Grant
    Filed: September 10, 2021
    Date of Patent: March 31, 2026
    Assignee: Alexion Pharmaceuticals, Inc.
    Inventors: David George Potter, Jennifer Ann Dzielawa, Brenda Sue Carter, Mark Ma
  • Patent number: 11965884
    Abstract: A method of quantitating free (unbound) human C5 complement protein (C5) from a sample comprising: binding biotinylated anti-C5 capture antibody to strepavidin-coated particles; capturing the free (unbound) C5 in the sample; detecting the captured free C5; and quantitating the captured free C5 using laser-induced fluorescence detection; wherein the method is performed in a Gyros Bioaffy 200 CD in a Gyrolab xPlore or a Gyrolab XP instrument.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: April 23, 2024
    Assignee: Alexion Pharmaceuticals, Inc.
    Inventors: Mark Dysinger, Mark Ma, Bruce A. Andrien
  • Patent number: 11951629
    Abstract: Systems, apparatuses, and methods for cost evaluation and motion planning for robotic devices are disclosed herein. According to at least one non-limiting exemplary embodiment, a method for producing and evaluating a continuous and differentiable total cost as a function of all available motion commands is disclosed and may be utilized in conjunction with a gradient descent to determine a minimum cost motion command corresponding to an optimal motion for a robotic device to execute in accordance with a target trajectory and obstacle avoidance.
    Type: Grant
    Filed: September 30, 2021
    Date of Patent: April 9, 2024
    Assignee: Brain Corporation
    Inventors: Oleg Sinyavskiy, Mark Ma, Tiger Lin
  • Publication number: 20240044920
    Abstract: Provided herein are antibodies which bind to ceruloplasmin and are useful for various applications, including detecting ceruloplasmin and immunocapturing ceruloplasmin in biological samples. The antibodies are useful in methods of measuring non-ceruloplasmin-bound copper concentrations and labile-bound copper concentrations in biological samples.
    Type: Application
    Filed: September 10, 2021
    Publication date: February 8, 2024
    Applicant: Alexion Pharmaceuticals, Inc.
    Inventors: David George Potter, Jennifer Ann Dzielawa, Brenda Sue Carter, Mark Ma
  • Publication number: 20230414654
    Abstract: This disclosure relates to methods of diagnosing and treating a copper metabolism-associated disease or disorder, such as Wilson disease (WD).
    Type: Application
    Filed: November 12, 2021
    Publication date: December 28, 2023
    Applicant: Alexion Pharmaceuticals, Inc.
    Inventors: Pan Wei-Jian, Mark Ma, Brian Meltzer, Eugene Scott Swenson, Scott Edward Mosley, Ryan Pelto, Adam Quicquaro, Guillermo del Angel, Hareesh Chamarthi
  • Patent number: 11828683
    Abstract: A method of quantitating free (unbound) human C5a complement protein (C5a) from a sample comprising: binding biotinylated anti-C5a capture antibody to strepavidin-coated particles; capturing the free (unbound) C5 in the sample; detecting the captured free C5a; and quantitating the captured free C5 using laser-induced fluorescence detection; wherein the method is performed in a Gyros Bioaffy 200 CD in a Gyrolab xPlore or a Gyrolab XP instrument; wherein human C5 is first removed from the sample.
    Type: Grant
    Filed: October 19, 2017
    Date of Patent: November 28, 2023
    Assignee: Alexion Pharmaceuticals, Inc.
    Inventors: Mark Dysinger, Mark Ma
  • Publication number: 20220334135
    Abstract: This disclosure relates to methods of measuring copper concentrations in biological samples. More particularly, this disclosure relates to methods of measuring non-ceruloplasmin-bound copper concentrations and/or labile-bound copper concentrations in biological samples. Such methods are particularly useful in management and treatment of metabolism-associated diseases or disorders.
    Type: Application
    Filed: September 11, 2020
    Publication date: October 20, 2022
    Applicant: Alexion Pharmaceuticals, Inc.
    Inventors: Mark Ma, Tao Liang, Ryan Pelto
  • Publication number: 20220016778
    Abstract: Systems, apparatuses, and methods for cost evaluation and motion planning for robotic devices are disclosed herein. According to at least one non-limiting exemplary embodiment, a method for producing and evaluating a continuous and differentiable total cost as a function of all available motion commands is disclosed and may be utilized in conjunction with a gradient descent to determine a minimum cost motion command corresponding to an optimal motion for a robotic device to execute in accordance with a target trajectory and obstacle avoidance.
    Type: Application
    Filed: September 30, 2021
    Publication date: January 20, 2022
    Inventors: Oleg Sinyavskiy, Mark Ma, Tiger Lin
  • Publication number: 20200333860
    Abstract: An information handling system includes a fan to generate airflow within the system, and an articulated duct component to modify the airflow. The information handling system further includes a baseboard management controller to selectively adjust an orientation of the articulated duct component based on operational parameters received at the controller.
    Type: Application
    Filed: April 18, 2019
    Publication date: October 22, 2020
    Inventors: Mark Ma, Eric M Tunks
  • Publication number: 20190250157
    Abstract: A method of quantitating free (unbound) human C5 complement protein (C5) from a sample comprising: binding biotinylated anti-C5 capture antibody to strepavidin-coated particles; capturing the free (unbound) C5 in the sample; detecting the captured free C5; and quantitating the captured free C5 using laser-induced fluorescence detection; wherein the method is performed in a Gyros Bioaffy 200 CD in a Gyrolab xPlore or a Gyrolab XP instrument.
    Type: Application
    Filed: October 19, 2017
    Publication date: August 15, 2019
    Inventors: Mark DYSINGER, Mark MA, Bruce A. ANDRIEN
  • Publication number: 20190242893
    Abstract: A method of quantitating free (unbound) human C5a complement protein (C5a) from a sample comprising: binding biotinylated anti-C5a capture antibody to strepavidin-coated particles; capturing the free (unbound) C5 in the sample; detecting the captured free C5a; and quantitating the captured free C5 using laser-induced fluorescence detection; wherein the method is performed in a Gyros Bioaffy 200 CD in a Gyrolab xPlore or a Gyrolab XP instrument; wherein human C5 is first removed from the sample.
    Type: Application
    Filed: October 19, 2017
    Publication date: August 8, 2019
    Inventors: Mark DYSINGER, Mark MA
  • Patent number: 9823628
    Abstract: A laboratory system and a method for controlling a laboratory system comprises multiple subsystems; each subsystem being configured to receive and carry out a command; and a master control device configured to process command groups and/or command(s) within the same command group simultaneously; to process command groups and/or command(s) of different command groups sequentially; and within a command group, to process command group(s) and/or command(s) grouped into a command group before processing other commands command group(s) and/or command(s).
    Type: Grant
    Filed: January 11, 2013
    Date of Patent: November 21, 2017
    Assignee: Tecan Trading AG
    Inventor: Mark Ma
  • Publication number: 20140200683
    Abstract: A laboratory system and a method for controlling a laboratory system comprises multiple subsystems; each subsystem being configured to receive and carry out a command; and a master control device configured to process command groups and/or command(s) within the same command group simultaneously; to process command groups and/or command(s) of different command groups sequentially; and within a command group, to process command group(s) and/or command(s) grouped into a command group before processing other commands command group(s) and/or command(s).
    Type: Application
    Filed: January 11, 2013
    Publication date: July 17, 2014
    Applicant: Tecan Trading AG
    Inventor: Mark MA
  • Patent number: 7694609
    Abstract: A hand-held device for extracting a base of a light bulb from a socket, including a body portion, circular in cross-section, and of a diameter which is easily grasped by the human hand; and constructed of rubber or the like material which does not convey electrical current; a rubber jacket over the body portion having protrusions to allow the user to have a firm, non-slip grip on the device when in use; each end being conically shaped end; the first end being of an increasing conical diameter, so as to allow the end to be inserted into a typically sized light bulb base, and the second end being of a slightly less conical diameter to allow the end to be inserted into smaller bulbs, such as Christmas tree or chandelier sized bulbs. Each of the two conical ends would be hollowed out to a certain extent. Further the surface of each conically shaped end would comprise a plurality of parallel ridges which would provide a firmer grip between the device and the bulb base.
    Type: Grant
    Filed: April 3, 2008
    Date of Patent: April 13, 2010
    Inventor: Mark Ma
  • Patent number: 6095060
    Abstract: A tray apparatus securable to the windshield via suction cups or the like, and for providing a second pair of suction cups which are adjustable in height to be attachable onto the dash board. There is further provided a framework which allows the tray to slide from the frame and rotate to a position below the dashboard at the level of the lap of a driver of a car. When not in use, the tray is returnable to the tray framework so that it may be stored atop the dashboard for further use. There are further included cup holders foldable out from the tray surface for supporting cups therein.
    Type: Grant
    Filed: November 9, 1998
    Date of Patent: August 1, 2000
    Inventor: Mark Ma
  • Patent number: 5795029
    Abstract: A method of assembling a chair back onto a chair bottom by providing a back portion of material having first and second end portions insertable into the chair bottom, boring a hole longitudinally into the ends of the back members, providing a bore transverse to the longitudinal bore on each of the end portions of the chair back, inserting peg member into the transverse bore, the peg member further including a threaded bore which aligns with the longitudinal bore when the member is positioned therein, providing a bolt member insertable into the longitudinal bore from the underside of the chair bottom and threadably engaging the peg member inserted therein, and threadably tightening the bolt member so that as the bolt member is tightened the chair back end portions are fulled in engagement with the chair bottom.
    Type: Grant
    Filed: August 8, 1996
    Date of Patent: August 18, 1998
    Inventor: Mark Ma
  • Patent number: 5465673
    Abstract: A collapsible stool apparatus having a plurality of leg members attached to a wooden seat, and further including a swivel bracket for allowing the legs of the apparatus to be moved from a substantially flat, parallel closed position to an "X" configured open position. There is further included a handle member secured to the lower face of the seat for carrying the stool apparatus when it is in the closed position.
    Type: Grant
    Filed: February 22, 1994
    Date of Patent: November 14, 1995
    Inventor: Mark Ma
  • Patent number: 5282592
    Abstract: A vessel holder for cups or the like, having a generally square or rectangular base portion for positioning on a flat surface such as the dashboard or a seat, a plurality of side members positionable from a storage position substantially horizontal against the upper face of the base, and movable to a substantially vertical position wherein a cup or a bottle may be placed within the space defined by the four upright members. It is further included a wire border which is a generally rectangular portion of wire positionable as a continuous border around the upper portions of the upright sides, in order to define a substantially continuous member in order to hold the side members in an upright position. Further, one of the ends of the upper border is somewhat truncated in order to define an opening in the sidewall so that a handle on the cup may extend therefrom.
    Type: Grant
    Filed: November 20, 1992
    Date of Patent: February 1, 1994
    Inventor: Mark Ma
  • Patent number: D436201
    Type: Grant
    Filed: February 15, 2000
    Date of Patent: January 9, 2001
    Inventor: Mark Ma
  • Patent number: D862743
    Type: Grant
    Filed: March 7, 2018
    Date of Patent: October 8, 2019
    Assignee: Lumileds Holding B.V.
    Inventors: Chunheng Kang, Colin Huang, Mark Ma, Xin Sheng, Song Yang