Patents by Inventor Mark Mamula

Mark Mamula has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ErbB peptide pharmaceutical and vaccine compositions and therapeutic uses thereof for cancer
    Patent number: 11890335
    Abstract: Disclosed herein are peptide-adjuvant pharmaceutical compositions and vaccine compositions that trigger long lasting natural anti-tumor antibodies. Such compositions may be used alone, or in combination with anti-cancer agents, chemotherapeutic agents, anti-PD therapy, chemotherapy, radiation therapy, and surgery, in the prevention and treatment of cancer.
    Type: Grant
    Filed: September 27, 2018
    Date of Patent: February 6, 2024
    Assignees: L2 Diagnostics, LLC, Yale University
    Inventors: Mark Mamula, Raymond A. Koski
  • ErbB PEPTIDE PHARMACEUTICAL AND VACCINE COMPOSITIONS AND THERAPEUTIC USES THEREOF FOR CANCER
    Publication number: 20200246444
    Abstract: Disclosed herein are peptide-adjuvant pharmaceutical compositions and vaccine compositions that trigger long lasting natural anti-tumor antibodies. Such compositions may be used alone, or in combination with anti-cancer agents, chemotherapeutic agents, anti-PD therapy, chemotherapy, radiation therapy, and surgery, in the prevention and treatment of cancer.
    Type: Application
    Filed: September 27, 2018
    Publication date: August 6, 2020
    Inventors: Mark MAMULA, Raymond A. KOSKI
  • Selectable ramjet propulsion system
    Patent number: 9726115
    Abstract: A selectable ramjet propulsion system for propelling a rocket or missile includes a gas generator adjacent a booster. A frangible diaphragm is disposed between the gas generator and the booster. The booster and fuel gas generator can be operated in normal sequence, or operated at the same time in order to increase the thrust produced for short-range missions. A logic circuit contained on the rocket or missile determines a time to rupture the frangible diaphragm based on whether or not the distance to the target exceeds a threshold distance.
    Type: Grant
    Filed: January 23, 2012
    Date of Patent: August 8, 2017
    Assignee: AEROJET ROCKETDYNE, INC.
    Inventors: Patrick W. Hewitt, Mark Mamula
  • Isoaspartyl repair
    Publication number: 20050053984
    Abstract: Methods for identifying markers for autoimmune disease which can include comparing the expression of the enzyme “protein carboxyl methyltransferase” (PCMT) in normal subjects to the expression of PCMT in persons diagnosed with an autoimmune disease and methods of diagnosing a subject for an autoimmune disease or a predisposition to an autoimmune disease.
    Type: Application
    Filed: July 2, 2004
    Publication date: March 10, 2005
    Inventor: Mark Mamula