Abstract: The present disclosure provides, inter alia, compositions and methods for treating or ameliorating the effect of a disorder such as, e.g., anxiety or depression in a subject, with less or no off- and/or on-target side effects. Also provided are methods for treating such disorder in a pregnant woman.

Abstract: Low cost spectacles may include a paper or plastic frame and injection molded plastic lens or lenses, where the lens may be easily removed and changed within the frame. In one example, the lens may have a round shape, and securing the lens within the frame may be accomplished by inserting the lens into the aperture in the frame, and rotating the lens, for example, by ¼ of a turn. The lens may have a flange extending radially outward from an edge of the lens, wrapping substantially around a circumference of the lens. The lens may further have a key extending radially outward from an edge of the lens. The key is configured to fit the lens into the aperture of the frame. When the lens is rotated within the aperture, a portion of the frame enters a channel between the key and the flange to secure the lens to the frame.

Abstract: A pair of glasses includes a paper frame having at least one aperture and a substrate arranged with each of said at least one aperture to magnify objects for a user when viewing through each of said at least one aperture.

Abstract: A solar viewing filter comprising a paperboard tube, and a paperboard disc having an aperture and film extending across the aperture, the paperboard disc being arranged within the paperboard tube to enable a user to view a solar event through the film when looking into the paperboard tube.

Abstract: A pair of glasses includes a paper frame having at least one aperture and a substrate arranged with each of said at least one aperture to magnify objects for a user when viewing through each of said at least one aperture.