Patents by Inventor Mark Matzas

Mark Matzas has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11572593
    Abstract: The present invention relates to a method of selectively amplifying at least one nucleic acid sequence of at least one microorganism and/or virus in a sample of a subject, wherein k-mers 3 are applied that show a difference in frequency and/or context in the genome 2 of the at least one microorganism and/or virus compared to the genome of the subject 1.
    Type: Grant
    Filed: November 28, 2017
    Date of Patent: February 7, 2023
    Assignee: Siemens Aktiengesellschaft
    Inventors: Carsten Dietrich, Yiwei Huang, Mark Matzas, Andreas Emanuel Posch
  • Publication number: 20220275460
    Abstract: Disclosed are methods of predicting a radiotherapy success in a method of treating a lung cancer of a patient, the use of specific markers for predicting a radiotherapy success in a method of treating a lung cancer of a patient, a database comprising the markers, and a computer program product for use in such a method.
    Type: Application
    Filed: July 31, 2020
    Publication date: September 1, 2022
    Applicants: Siemens Healthcare GmbH, The Cleveland Clinic Foundation
    Inventors: Matthias SIEBERT, Carsten DIETRICH, Heike WEHNER, Jens-Christoph GEORGI, Mohamed ABAZEED, Andreas Emanuel POSCH, Andreas KAPPEL, Mark MATZAS
  • Patent number: 10876110
    Abstract: The invention relates to methods and devices for preparing synthetic nucleic acids.
    Type: Grant
    Filed: March 21, 2017
    Date of Patent: December 29, 2020
    Assignee: Codex DNA, Inc.
    Inventors: Peer F. Staehler, Raphael Carapito, Cord F. Staehler, Mark Matzas, Jack T. Leonard, Joachim Jaeger, Markus Beier
  • Patent number: 10604853
    Abstract: The invention relates to a method for converting carbon dioxide and water, wherein the electrolyte comprises a proton sponge which serves to accumulate CO2 in the electrolyte. The invention further relates to a corresponding use of a proton sponge and to an electrolyte comprising at least one proton sponge.
    Type: Grant
    Filed: November 18, 2014
    Date of Patent: March 31, 2020
    Assignee: SIEMENS AKTIENGESELLSCHAFT
    Inventors: Maximilian Fleischer, Philipp Groenninger, Ralf Krause, Mark Matzas, Guenter Schmid, Kerstin Wiesner
  • Publication number: 20190345569
    Abstract: The present invention relates to a method of selectively amplifying at least one nucleic acid sequence of at least one microorganism and/or virus in a sample of a subject, wherein k-mers 3 are applied that show a difference in frequency and/or context in the genome 2 of the at least one microorganism and/or virus compared to the genome of the subject 1.
    Type: Application
    Filed: November 28, 2017
    Publication date: November 14, 2019
    Inventors: Carsten Dietrich, Yiwei Huang, Mark Matzas, Andreas Emanuel Posch
  • Publication number: 20180185838
    Abstract: A biochemical analytical device and a biochemical analytical method for determining an analyte in a test sample are provided. In the technique, the biochemical analytical device includes a sample port to receive the test sample, a sensor to probe the test sample and to generate sensor data, and a processor. The sensor data corresponds to the analyte in the test sample. The processor receives the sensor data from the sensor and selects a non-linear function for the received sensor data. The processor fits the selected non-linear function to the sensor data. Additionally, the processor compares the fitted non-linear function to a reference data to determine the analyte in the test sample.
    Type: Application
    Filed: July 2, 2015
    Publication date: July 5, 2018
    Inventors: Ralph Grothmann, Walter Gumbrecht, Mark Matzas, Peter Paulicka, Stefanie Vogl, Hans-Georg Zimmermann
  • Publication number: 20170267999
    Abstract: The invention relates to methods and devices for preparing synthetic nucleic acids.
    Type: Application
    Filed: March 21, 2017
    Publication date: September 21, 2017
    Inventors: Peer F. STAEHLER, Raphael CARAPITO, Cord F. STAEHLER, Mark MATZAS, Jack T. LEONARD, Joachim JAEGER, Markus BEIER
  • Publication number: 20160376714
    Abstract: The invention relates to a method for converting carbon dioxide and water, wherein the electrolyte comprises a proton sponge which serves to accumulate CO2 in the electrolyte. The invention further relates to a corresponding use of a proton sponge and to an electrolyte comprising at least one proton sponge.
    Type: Application
    Filed: November 18, 2014
    Publication date: December 29, 2016
    Applicant: Siemens Aktiengesellschaft
    Inventors: Maximilian Fleischer, Philipp Groenninger, Ralf Krause, Mark Matzas, Guenter Schmid, Kerstin Wiesner
  • Publication number: 20140163200
    Abstract: The invention relates to a method for the sequence information of PNA molecules of a specific PNA molecule species, wherein, the PNA molecules are contacted with different nucleic acid molecule species comprising nucleic acid molecules with nucleotides, wherein the nucleic acid molecules partially comprise a nucleic acid sequence that is complementary to a partial sequence of the PNA molecule, wherein nucleic acid molecules having complementary sequences bind to the PNA molecules forming nucleic acid/PNA hybrids, wherein nucleic acid molecules with non-complementary sequences are separated from the hybrids, wherein thereafter the hybrids are dissociated into single stranded hybrid nucleic acid molecules and PNA molecules, wherein the single stranded hybrid nucleic acid molecules are subjected to a sequencing process providing hybrid sequence information about the single stranded hybrid nucleic acid sequence, and wherein the hybrid sequence information is optionally translated into the complementary PNA sequen
    Type: Application
    Filed: November 7, 2013
    Publication date: June 12, 2014
    Applicants: PLS-Design GmbH, RiNA NETZWERK RNA-TECHNOLOGIEN GMBH
    Inventors: Reinhard Bredehorst, Jom Glockler, Thomas Grunwald, Mark Matzas, Edzard Spillner
  • Publication number: 20110092380
    Abstract: The invention relates to improved molecular-biological processing equipment and an improved method of processing biological samples. The invention combines the provision of biologically functional molecules such as nucleic acids and peptides and of derivatives or analogs of these two classes of molecules in miniaturized flow cells with the sequential addition of reagents or fluids and serves for the processing of biological samples, such as proteins, nucleic acids, biogenic small molecules such as e.g. metabolites, viruses or cells, which for this purpose are introduced into the miniaturized flow cells.
    Type: Application
    Filed: December 31, 2007
    Publication date: April 21, 2011
    Applicant: FEBIT HOLDING GMBH
    Inventors: Peer Stahler, Markus Beier, Cord Stahler, Daniel Summerer, Mark Matzas, Sonja Vorwerk
  • Publication number: 20100256012
    Abstract: The invention relates to an extraction method for isolating target molecules from a sample with the help of a molecule library.
    Type: Application
    Filed: November 24, 2008
    Publication date: October 7, 2010
    Applicant: FEBIT HOLDING GMBH
    Inventors: Markus Beier, Stephan Bau, Daniel Summerer, Mark Matzas, Peer F. Staehler
  • Publication number: 20100216648
    Abstract: The invention relates to methods and devices for preparing synthetic nucleic acids.
    Type: Application
    Filed: February 19, 2010
    Publication date: August 26, 2010
    Applicant: FEBIT HOLDING GMBH
    Inventors: Peer F. STAEHLER, Raphael CARAPITO, Cord F. STAEHLER, Mark MATZAS, Jack T. LEONARD, Joachim JAEGER, Markus BEIER
  • Publication number: 20100081801
    Abstract: The invention relates to a method for determining an unknown PNA sequence information of PNA molecules of a specific PNA molecule species, wherein, the PNA molecules are contacted with one or several different nucleic acid molecule species comprising nucleic acid molecules with at least one nucleotide, wherein the nucleic acid molecules at least partially comprise a nucleic acid sequence that is complementary to at least a partial sequence of the PNA molecule, wherein nucleic acid molecules having complementary sequences bind to the PNA molecules forming nucleic acid/PNA hybrids, wherein nucleic acid molecules with non-complementary sequences are separated from the nucleic acid/PNA hybrids, wherein thereafter the nucleic acid/PNA hybrids are dissociated into single stranded hybrid nucleic acid molecules and PNA molecules, wherein the single stranded hybrid nucleic acid molecules are subjected to a sequencing process providing hybrid sequence information about the single stranded hybrid nucleic acid sequence,
    Type: Application
    Filed: October 17, 2006
    Publication date: April 1, 2010
    Applicants: RiNA Netzwerk RNA-Technologien GmbH, PLS-Design GmbH
    Inventors: Reinhard Bredehorst, Jorn Glokler, Thomas Grunwald, Mark Matzas, Edzard Spillner