Abstract: A fluidic cartridge is provided, comprising: a fluidic chamber including a first fluidic compartment and a semipermeable membrane separating the first fluidic compartment from a second fluidic compartment, wherein the semipermeable membrane is non-permeable for liquid and permeable for air, and wherein the second fluidic compartment is a closed compartment configured for accumulating air, and a pumping device configured for pumping a liquid into the first fluidic compartment such that the first fluidic compartment is filled with the liquid, whereby air contained in the first fluidic compartment is forced through the semipermeable membrane into the second fluidic compartment and accumulates in the second fluidic compartment such that a pressure within the second fluidic compartment increases, and a fluidic discharge line coupled to the first fluidic compartment and configured for discharging the first fluidic compartment using the pressure within the second fluidic compartment.

Abstract: Purifying target biomolecules, such as nucleic acids or proteins, from a biological source is a time intensive process and is typically performed by a skilled technician or scientist owing to the highly technical nature of the work. Systems, devices, and methods disclosed herein enable the automated bioprocessing and purification of target biomolecules from a biological source. For example, an instrument and disposable cartridge are provided for automatedly isolating and purifying nucleic acids (such as plasmid DNA from a bacterial culture) or for isolating protein from any biological sample. Such an exemplary instrument and cartridge can work in concert to timely release, mix, and move the target biomolecule and various reagents and buffers through a target biomolecule purification process, resulting in a purified target biomolecule with less manual oversight than traditional approaches.

Abstract: Purifying target biomolecules, such as nucleic acids or proteins, from a biological source is a time intensive process and is typically performed by a skilled technician or scientist owing to the highly technical nature of the work. Systems, devices, and methods disclosed herein enable the automated bioprocessing and purification of target biomolecules from a biological source. For example, an instrument and disposable cartridge are provided for automatedly isolating and purifying nucleic acids (such as plasmid DNA from a bacterial culture) or for isolating protein from any biological sample. Such an exemplary instrument and cartridge can work in concert to timely release, mix, and move the target biomolecule and various reagents and buffers through a target biomolecule purification process, resulting in a purified target biomolecule with less manual oversight than traditional approaches.

Abstract: Purifying target biomolecules, such as nucleic acids or proteins, from a biological source is a time intensive process and is typically performed by a skilled technician or scientist owing to the highly technical nature of the work. Systems, devices, and methods disclosed herein enable the automated bioprocessing and purification of target biomolecules from a biological source. For example, an instrument and disposable cartridge are provided for automatedly isolating and purifying nucleic acids (such as plasmid DNA from a bacterial culture) or for isolating protein from any biological sample. Such an exemplary instrument and cartridge can work in concert to timely release, mix, and move the target biomolecule and various reagents and buffers through a target biomolecule purification process, resulting in a purified target biomolecule with less manual oversight than traditional approaches.

Abstract: Provided herein are analyzers as well as related methods for measuring both an absorbance and emission of a sample. The analyzer includes light sources for epi-illumination and transillumination of the sample, and detectors for measuring the intensities of excitation, emission, and transillumination light. A dichroic mirror permits a portion of the excitation light to transmit to a detector that monitors changes in excitation light intensity. Temperature sensors allow for signal corrections based on temperature variations of the detectors and sample.

Abstract: Purifying target biomolecules, such as nucleic acids or proteins, from a biological source is a time intensive process and is typically performed by a skilled technician or scientist owing to the highly technical nature of the work. Systems, devices, and methods disclosed herein enable the automated bioprocessing and purification of target biomolecules from a biological source. For example, an instrument and disposable cartridge are provided for automatedly isolating and purifying nucleic acids (such as plasmid DNA from a bacterial culture) or for isolating protein from any biological sample. Such an exemplary instrument and cartridge can work in concert to timely release, mix, and move the target biomolecule and various reagents and buffers through a target biomolecule purification process, resulting in a purified target biomolecule with less manual oversight than traditional approaches.

Abstract: Provided herein are analyzers as well as related methods for measuring both an absorbance and emission of a sample. The analyzer includes light sources for epi-illumination and transillumination of the sample, and detectors for measuring the intensities of excitation, emission, and transillumination light. A dichroic mirror permits a portion of the excitation light to transmit to a detector that monitors changes in excitation light intensity. Temperature sensors allow for signal corrections based on temperature variations of the detectors and sample.

Abstract: A method and apparatus for selectively configuring, in a router, physical ports to either a Wide Area Network (WAN) or a Local Area Network (LAN). Method steps include receiving a message to configure a physical port for use with either the LAN or WAN; associating, in response to receiving the message, a set of mapping assignments for using the physical port to access the network; and implementing the mapping assignments, in response to associating the mapping assignments, to configure the physical port for coupling to the network.

Abstract: Method (300) and apparatus for validating application level gateway files or firewall rulsets. The method and apparatus include receiving at a bidirectional communications device, an application level gateway file, and comparing at least one compatibility parameter of said ALG file with features of said bi-directional communications device. In an instance where all of the compatibility parameters compare favorably, the ALG file is stored at the bidirectional communications device.

Abstract: A security system for use in a distributed network includes a service provider selectively accessible via a network by a plurality of end users each having an access device for accessing the network. A control mechanism is included which is disposed at a location of the service provider and accesses and modifies stored information on each access device of the end users to designate portions of the information to prevent access thereof by the end users.