Patents by Inventor Mark McDonnell

Mark McDonnell has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Tricyclic Delta-Opioid Modulators
    Publication number: 20090042871
    Abstract: The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic ?-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Application
    Filed: October 9, 2008
    Publication date: February 12, 2009
    Inventors: Steven J. Coats, Scott L. Dax, Bart DeCorte, Li Liu, Mark McDonnell, James J. McNally
  • TRICYCLIC DELTA-OPIOID MODULATORS
    Publication number: 20080318937
    Abstract: The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic ?-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Application
    Filed: August 22, 2008
    Publication date: December 25, 2008
    Inventors: Steven J. Coats, Scott L. Dax, Bart DeCorte, Li Liu, Mark McDonnell, James J. McNally
  • TRICYCLIC DELTA- OPIOID MODULATORS
    Publication number: 20080306111
    Abstract: The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic ?-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Application
    Filed: August 7, 2008
    Publication date: December 11, 2008
    Inventors: John R. Carson, Scott L. Dax, Bart DeCorte, Li Liu, Mark McDonnell, James McNally
  • QUINOLINE-DERIVED AMIDE MODULATORS OF VANILLOID VR1 RECEPTOR
    Publication number: 20080300236
    Abstract: This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to quinoline-derived amides that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.
    Type: Application
    Filed: July 16, 2008
    Publication date: December 4, 2008
    Inventors: Ellen Codd, Scott L. Dax, Michele Jetter, Mark McDonnell, James J. McNally, Mark Youngman
  • Tricyclic ?- opioid modulators
    Patent number: 7439239
    Abstract: Disclosed are compounds, compositions and methods for treating various diseases and conditions, including pain. Such compounds are represented by Formula I as follows: wherein A, G, Y, R3-R5 are defined herein.
    Type: Grant
    Filed: December 21, 2005
    Date of Patent: October 21, 2008
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Steve Coats, Scott L. Dax, Bart DeCorte, Li Liu, Mark McDonnell, James J. McNally
  • Piperdinyl-phenoxazine and phenothiazine derivatives as ?-opioid modulators
    Patent number: 7432257
    Abstract: The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic ?-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Grant
    Filed: January 5, 2006
    Date of Patent: October 7, 2008
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Steve J. Coats, Scott L. Dax, Bart DeCorte, Li Liu, Mark McDonnell, James J. McNally
  • AMINOTETRALIN-DERIVED UREA MODULATORS OF VANILLOID VR1 RECEPTOR
    Publication number: 20080097102
    Abstract: This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to ?-aminotetralin-derived ureas that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.
    Type: Application
    Filed: October 23, 2007
    Publication date: April 24, 2008
    Inventors: Ellen Codd, Scott Dax, Michele Jetter, Mark McDonnell, James McNally, Mark Youngman
  • Naphthol, quinoline and isoquinoline-derived urea modulators of vanilloid VR1 receptor
    Patent number: 7183411
    Abstract: This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to naphthol, quinoline and isoquinoline-derived ureas that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.
    Type: Grant
    Filed: July 10, 2003
    Date of Patent: February 27, 2007
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Ellen Codd, Scott L. Dax, Michele Jetter, Mark McDonnell, James J. McNally, Mark Youngman
  • Perforator
    Publication number: 20070000364
    Abstract: Various embodiments of a perforator are disclosed.
    Type: Application
    Filed: July 1, 2005
    Publication date: January 4, 2007
    Inventors: Wade Powell, Scott Carter, Mark McDonnell
  • TRICYCLIC OPIOID MODULATORS
    Publication number: 20060287297
    Abstract: The invention is directed to compounds of Formula (I) useful as delta and mu opioid receptor modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Application
    Filed: June 15, 2006
    Publication date: December 21, 2006
    Inventors: Bart DeCorte, Li Liu, Mark McDonnell, Jim McNally
  • Tricyclic delta-opioid modulators
    Publication number: 20060148823
    Abstract: The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic ?-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Application
    Filed: January 5, 2006
    Publication date: July 6, 2006
    Inventors: Steven Coats, Scott Dax, Bart DeCorte, Li Liu, Mark McDonnell, James McNally
  • Tricyclic delta-opioid modulators
    Publication number: 20060135763
    Abstract: The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic ?-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Application
    Filed: December 21, 2005
    Publication date: June 22, 2006
    Inventors: Steve Coats, Scott Dax, Bart DeCorte, Li Liu, Mark McDonnell, James McNally
  • Tricyclic delta-opioid modulators
    Publication number: 20060135522
    Abstract: The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic ?-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Application
    Filed: December 21, 2005
    Publication date: June 22, 2006
    Inventors: John Carson, Scott Dax, Bart DeCorte, Li Liu, Mark McDonnell, James McNally
  • Tricyclic delta-opioid modulators
    Publication number: 20060135524
    Abstract: The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic ?-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Application
    Filed: December 21, 2005
    Publication date: June 22, 2006
    Inventors: John Carson, Scott Dax, Bart DeCorte, Li Liu, Mark McDonnell, James McNally
  • Tricyclic delta-opioid modulators
    Publication number: 20060030585
    Abstract: The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic ?-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Application
    Filed: August 2, 2005
    Publication date: February 9, 2006
    Inventors: Scott Dax, Bart DeCorte, Li Liu, Mark McDonnell, James McNally
  • Aminotetralin-derived urea modulators of vanilloid VR1 receptor
    Patent number: 6984647
    Abstract: This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to ?-aminotetralin-derived ureas that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.
    Type: Grant
    Filed: May 15, 2003
    Date of Patent: January 10, 2006
    Assignee: Janssen Pharmaceutica N.V.
    Inventors: Scott L. Dax, Michele Jetter, Mark McDonnell, James J. McNally, Mark Youngman
  • Aminotetralin-derived urea modulators of vanilloid VR1 receptor
    Publication number: 20050187291
    Abstract: This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to ?-aminotetralin-derived ureas that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.
    Type: Application
    Filed: January 28, 2005
    Publication date: August 25, 2005
    Inventors: Ellen Codd, Scott Dax, Michele Jetter, Mark McDonnell, James McNally, Mark Youngman
  • Tricyclic delta-opioid modulators
    Publication number: 20050009860
    Abstract: The invention is directed to delta opioid receptor modulators. More specifically, the invention relates to tricyclic ?-opioid modulators. Pharmaceutical and veterinary compositions and methods of treating mild to severe pain and various diseases using compounds of the invention are also described.
    Type: Application
    Filed: June 22, 2004
    Publication date: January 13, 2005
    Inventors: John Carson, Ellen Codd, Christine Razler, Andrea Works, Mark McDonnell, James McNally
  • Quinoline-derived amide modulators of vanilloid VR1 receptor
    Publication number: 20040192728
    Abstract: This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to quinoline-derived amides that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.
    Type: Application
    Filed: February 2, 2004
    Publication date: September 30, 2004
    Inventors: Ellen Codd, Scott L. Dax, Michele Jetter, Mark McDonnell, James J. McNally, Mark Youngman
  • Naphthol, quinoline and isoquinoline-derived urea modulators of vanilloid VR1 receptor
    Publication number: 20040157865
    Abstract: This invention is directed to vanilloid receptor VR1 ligands. More particularly, this invention relates to naphthol, quinoline and isoquinoline-derived ureas that are potent antagonists or agonists of VR1 which are useful for the treatment and prevention of inflammatory and other pain conditions in mammals.
    Type: Application
    Filed: July 10, 2003
    Publication date: August 12, 2004
    Inventors: Ellen Codd, Scott L. Dax, Michele Jetter, Mark McDonnell, James J. McNally, Mark Youngman