Patents by Inventor Mark McKinlay

Mark McKinlay has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method of Treatment
    Publication number: 20160161495
    Abstract: A method of diagnosing and treating proliferative disorders in connection with the use of a Smac mimetic.
    Type: Application
    Filed: July 30, 2014
    Publication date: June 9, 2016
    Applicant: Health Researc Inc.
    Inventors: C. Glenn Begley, Srinivas Chunduru, Mark McKinlay, Hans Minderman, Yasuhiro Mitsuuchi, David Weng
  • Smac Mimetic Therapy
    Publication number: 20130196927
    Abstract: A Smac mimetic therapy wherein the Smac mimetic is selected and developed based at least in part on its cIAP degradation properties.
    Type: Application
    Filed: January 28, 2013
    Publication date: August 1, 2013
    Inventors: Christopher BENETATOS, Srinivas CHUNDURU, Stephen CONDON, Mark McKINLAY, Yasuhiro MITSUUCHI
  • TREATMENT OF PROLIFERATIVE DISORDERS
    Publication number: 20130040893
    Abstract: Inhibitors of cIAP-1 and methods and compositions for treating proliferative disorders.
    Type: Application
    Filed: April 13, 2012
    Publication date: February 14, 2013
    Applicant: TETRALOGIC PHARMACEUTICALS CORPORATION
    Inventors: Stacy SPRINGS, Mark McKINLAY, Sri CHUNDURU, Chris BENETATOS
  • METHOD OF TREATMENT
    Publication number: 20110287001
    Abstract: The invention provides methods for inducing apoptosis, comprising treatment of a patient with a TNF? inhibitor as well as with an IAP inhibitor and a TRAIL receptor agonist. The methods ameliorate the risk of unwanted effects, thereby resulting in an improved therapeutic index for IAP inhibitors in combination with a TRAIL receptor agonist.
    Type: Application
    Filed: August 5, 2009
    Publication date: November 24, 2011
    Applicants: TETRALOGIC PHARMACEUTICALS, AMGEN INC.
    Inventors: Pamela M. Holland, Julia C. Piasecki, Christopher A. Benetatos, Srinivas K. Chunduru, Mark A. McKinlay
  • TNFalpha GENE EXPRESSION AS A BIOMARKER OF SENSITIVITY TO ANTAGONISTS OF INHIBITOR OF APOPTOSIS PROTEINS
    Publication number: 20110008802
    Abstract: TNF? gene expression can be used as a biomarker of a cell's sensitivity to antagonists of inhibitor of apoptosis proteins (IAPs). Methods of the invention are useful for screening patients to identify those who could benefit from administration of an IAP antagonist to treat various malignant or benign tumors, benign proliferative diseases, or autoimmune diseases.
    Type: Application
    Filed: May 7, 2008
    Publication date: January 13, 2011
    Applicant: TETRALOGIC PHARMACEUTICALS CORP.
    Inventors: Alireza Alavi, Mark A. McKinlay, Srinivas K. Chunduru, John Silke, David Vaux, James Vince
  • TREATMENT OF PROLIFERATIVE DISORDERS
    Publication number: 20100256046
    Abstract: Inhibitors of cIAP-1 and methods and compositions for treating proliferative disorders.
    Type: Application
    Filed: April 3, 2009
    Publication date: October 7, 2010
    Applicant: TETRALOGIC PHARMACEUTICALS CORPORATION
    Inventors: Stacy SPRINGS, Mark McKINLAY, Sri CHUNDURU, Chris BENETATOS
  • BUSINESS METHODS FOR COMPOUNDS FOR TREATMENT OF PROLIFERATIVE DISORDERS
    Publication number: 20070203749
    Abstract: Methods and systems for marketing pharmaceutical compositions including cIAP binding compounds are described herein.
    Type: Application
    Filed: February 14, 2007
    Publication date: August 30, 2007
    Inventors: Sri Chunduru, Mark McKinlay, Stacy Springs, Chris Benetatos, Stephen Condon
  • TREATMENT OF PROLIFERATIVE DISORDERS
    Publication number: 20070042428
    Abstract: Inhibitors of cIAP-1 and methods and compositions for treating proliferative disorders.
    Type: Application
    Filed: August 9, 2006
    Publication date: February 22, 2007
    Inventors: Stacy Springs, Mark McKinlay, Sri Chunduru, Chris Benetatos
  • Methods of reducing rhinovirus contagion and related compositions
    Publication number: 20060167109
    Abstract: The present invention relates to the use of pleconaril to reduce the contagion of rhinovirus virions shed from a host infected with a rhinovirus and thereby reduce disease transmission or re-infection.
    Type: Application
    Filed: February 14, 2003
    Publication date: July 27, 2006
    Inventors: Daniel Pevear, Gerald Rhodes, Theodore Nitz, Mark McKinlay, Marc Collett