Abstract: The present disclosure provides high-load tablet formulations of AG10 or a pharmaceutically acceptable salt thereof. In some aspects, provided herein are table formulations of AG10 or a pharmaceutically acceptable salt thereof that include at least 40% or more AG10 by weight and at least one pharmaceutical excipient selected from one or more fillers, one or more binders, one or more disintegrants, and one or more lubricants.

Abstract: An aqueous emulsion system substantially or completely devoid of an oil phase. The aqueous emulsion can be used as a platform to solubilize poorly water-soluble chemical compounds for use in a variety of fields, including pharmaceutical, cosmetic, skin care, personal care, food, and industrial arenas. The aqueous emulsion can be delivered to a human or animal via a variety of modes to treat a diverse number of ailments, such as a topical composition to promote hair growth or treat skin disorders. Stable and transparent formulations of the aqueous nano-emulsions described herein can be used to treat and/or prevent hair loss, to treat warts and cold sores, or to treat varicose veins.

Abstract: The present disclosure provides high-load tablet formulations of AG10 or a pharmaceutically acceptable salt thereof. In some aspects, provided herein are table formulations of AG10 or a pharmaceutically acceptable salt thereof that include at least 40% or more AG10 by weight and at least one pharmaceutical excipient selected from one or more fillers, one or more binders, one or more disintegrants, and one or more lubricants.

Abstract: A process for producing a solid dispersion of a material by spraying the material onto a fluidized cloud of carrier particles in a fluid bed. The fluidized cloud of carrier particles is formed by adding a solid or liquid carrier to a fluid bed. The material to be sprayed is in a liquid or gas form. The process is especially applicable to the formation of amorphous solid powder pharmaceutical ingredients.

Abstract: The present disclosure relates to novel crystalline salt forms of lamivudine, methods for the preparation thereof, pharmaceutical compositions thereof, and their use in the treatment of viruses such as Human Immunodeficiency Virus (HIV) infection.