Patents by Inventor Mark Miles

Mark Miles has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20190209547
    Abstract: The present disclosure relates to a method of treating advanced renal cell carcinoma (RCC) in human patients who have received prior anti-angiogenic therapy using CABOMETYX, a kinase inhibitor.
    Type: Application
    Filed: April 17, 2017
    Publication date: July 11, 2019
    Inventors: Dana T. Aftab, Gisela Schwab, Colin Hessel, Christian Scheffold, Steven Lacy, Dale Miles, Alan Arroyo, Mark Dean
  • Patent number: 10300450
    Abstract: The present disclosure provides apparatuses, systems, and methods involving a spotter for depositing a substance on a submerged surface. The spotter comprises an outlet cavity defined at least in part by a spotting orifice, a first opening, and a second opening. The spotter also comprises a first conduit fluidly coupled to the first opening and a second conduit fluidly coupled to the second opening. The spotter is adapted so that fluid flowing through the first conduit and the second conduit is communicated among the first opening, the second opening, and a submerged deposition surface when the sealing orifice is sealed against the submerged deposition surface to form a deposition spot on the submerged deposition surface. The submerged deposition surface is within a liquid such that the liquid covers the deposition spot upon removal of the orifice from the deposition surface.
    Type: Grant
    Filed: September 13, 2013
    Date of Patent: May 28, 2019
    Assignee: Carterra, Inc.
    Inventors: Bruce K. Gale, Joshua W. Eckman, Adam Miles, Christopher Morrow, James Smith, Sriram Natarajan, Mark Eddings
  • Patent number: 10300479
    Abstract: The present disclosure provides apparatuses, systems, and methods involving a spotter apparatus for depositing a substance from a carrier fluid onto a deposition surface in an ordered array. The spotter apparatus includes a loading surface, including a first well and a second well, and a different outlet surface, including a first opening and a second opening, where a first microconduit fluidly couples the first well with the first opening and a second microconduit fluidly couples the second well with the second opening. An overlay is sealed to the outlet surface and penetrated by a deposition channel that is situated to communicate carrier fluid among the first opening, the second opening, and the deposition surface when the overlay is pressed against the deposition surface.
    Type: Grant
    Filed: June 8, 2017
    Date of Patent: May 28, 2019
    Assignee: Carterra, Inc.
    Inventors: Bruce Kent Gale, Adam Miles, Joshua Wayne Eckman, Sriram Natarajan, Jim Smith, Mark Eddings
  • Publication number: 20180357424
    Abstract: An Initialization Unit (IU) initiates an initial secure connection with an Intrinsic Use Control (IUC) Chip based on very large random numbers (VLRNs). The IUC Chip in turn initiates a secondary secure connection between it and one or more Use Controlled Components (UCCs). Polling by the IU allows confirmation of an ongoing secure connection, and also allows the IUC Chip to confirm the secondary secure connection to the UCCs. Removal or improper polling response from one of the UCCs results in a response from the IUC Chip that may include notification of tampering, or temporary or permanent discontinued operation of the offending UCC. Permanent discontinued operation may include destruction of the offending UCC, and cascaded discontinued operation of all other UCCs secured by the IUC Chip. A UCC may in turn be another nested layer of IUC Chips, controlling a corresponding layer of UCCs, ad infinitum.
    Type: Application
    Filed: July 12, 2018
    Publication date: December 13, 2018
    Applicant: LAWRENCE LIVERMORE NATIONAL SECURITY, LLC
    Inventor: Mark Miles Hart
  • Patent number: 10102382
    Abstract: An Initialization Unit (IU) initiates an initial secure connection with an Intrinsic Use Control (IUC) Chip based on very large random numbers (VLRNs). The IUC Chip in turn initiates a secondary secure connection between it and one or more Use Controlled Components (UCCs). Polling by the IU allows confirmation of an ongoing secure connection, and also allows the IUC Chip to confirm the secondary secure connection to the UCCs. Removal or improper polling response from one of the UCCs results in a response from the IUC Chip that may include notification of tampering, or temporary or permanent discontinued operation of the offending UCC. Permanent discontinued operation may include destruction of the offending UCC, and cascaded discontinued operation of all other UCCs secured by the IUC Chip. A UCC may in turn be another nested layer of IUC Chips, controlling a corresponding layer of UCCs, ad infinitum.
    Type: Grant
    Filed: August 31, 2015
    Date of Patent: October 16, 2018
    Assignee: Lawrence Livermore National Security, LLC
    Inventor: Mark Miles Hart
  • Publication number: 20170108288
    Abstract: A heat exchanger system, comprising: a storage tank; and heat exchanger apparatus comprising: a heat exchanger; and a plenum structure defining a hollow body comprising a first end that is coupled to the heat exchanger, and a second end remote from the first end; a mounting arrangement to mount the heat exchanger apparatus within the tank in an orientation wherein the heat exchanger is disposed in substantially a horizontal condition, whereas the plenum structure is disposed in substantially a vertical condition.
    Type: Application
    Filed: October 14, 2016
    Publication date: April 20, 2017
    Inventor: Mark MILES
  • Publication number: 20160188056
    Abstract: A method of electronically displaying glyphs. The method includes receiving a glyph spacing, moving a first glyph toward a second glyph along an axis, identifying an intersection of a first axis coordinate of the first glyph with a second axis coordinate of the second glyph, and moving at least one of the glyphs along the axis to separate the first and second axis coordinates of the respective first and second glyphs by the glyph spacing.
    Type: Application
    Filed: March 9, 2016
    Publication date: June 30, 2016
    Inventors: George Willard Keenan, Jim Allen Colby, Matthew B. Strong, Daniel Torgerson, Garth Braithwaite, Daniel Hatch, Andrew Branch, Randall Wright, Sean Thayne, Emerson Tyler Wright, Jeremiah Stephenson, Mark Miles, Mac Sims
  • Patent number: 9286861
    Abstract: A method of electronically displaying glyphs. The method includes receiving a glyph spacing, moving a first glyph toward a second glyph along an axis, identifying an intersection of a first axis coordinate of the first glyph with a second axis coordinate of the second glyph, and moving at least one of the glyphs along the axis to separate the first and second axis coordinates of the respective first and second glyphs by the glyph spacing.
    Type: Grant
    Filed: January 27, 2012
    Date of Patent: March 15, 2016
    Assignee: Provo Craft and Novelty, Inc.
    Inventors: George Willard Keenan, Jim Allen Colby, Matthew B. Strong, Daniel Torgerson, Garth Braithwaite, Daniel Hatch, Andrew Branch, Randall Wright, Sean Thayne, Emerson Tyler Wright, Jeremiah Stephenson, Mark Miles, Mac Sims
  • Publication number: 20150093509
    Abstract: Compositions and methods for changing the color of non-wood substrates. A one step method uses a solution of a water soluble pigment or dye and a metal salt. The non-toxic solution can be sprayed on a primed or unprimed substrate without wiping. The method can produce an even color on a smooth substrate, or a simulated woodgrain pattern or color on a textured substrate. The composition and method can be used on substrates as varied as fiberboard, fiberglass, steel, vinyl, plastics, metals, concrete, brick, stone, and stucco. The composition can include a resin which is emulsified when added and subsequently demulsifies. A two step method includes the additional step of applying a gall ink to the substrate. The compositions can be distributed as kits containing multiple packages of dry or concentrated ingredients, which make the final composition(s) when hydrated.
    Type: Application
    Filed: October 1, 2014
    Publication date: April 2, 2015
    Inventors: Edward A. Kennedy, Charles J. Villanueva, William Mark Miles, Kano Jessica Garrett, Michelle A. Bilder
  • Patent number: 8682130
    Abstract: A package structure and method of packaging for an interferometric modulator. A thin film material is deposited over an interferometric modulator and transparent substrate to encapsulate the interferometric modulator. A gap or cavity between the interferometric modulator and the thin film provides a space in which mechanical parts of the interferometric modulator may move. The gap is created by removal of a sacrificial layer that is deposited over the interferometric modulator.
    Type: Grant
    Filed: September 13, 2011
    Date of Patent: March 25, 2014
    Assignee: QUALCOMM Mems Technologies, Inc.
    Inventors: Lauren Palmateer, William J. Cummings, Brian Gally, Mark Miles, Jeffrey B. Sampsell, Clarence Chui, Manish Kothari
  • Publication number: 20120198545
    Abstract: A method of electronically displaying glyphs. The method includes receiving a glyph spacing, moving a first glyph toward a second glyph along an axis, identifying an intersection of a first axis coordinate of the first glyph with a second axis coordinate of the second glyph, and moving at least one of the glyphs along the axis to separate the first and second axis coordinates of the respective first and second glyphs by the glyph spacing.
    Type: Application
    Filed: January 27, 2012
    Publication date: August 2, 2012
    Applicant: Provo Craft and Novelty, Inc.
    Inventors: George Willard Keenan, Jim Allen Colby, Matthew B. Strong, Daniel Torgerson, Garth Braithwaite, Daniel Hatch, Andrew Branch, Randall Wright, Sean Thayne, Emerson Tyler Wright, Jeremiah Stephenson, Mark Miles, Mac Sims
  • Publication number: 20120002266
    Abstract: A package structure and method of packaging for an interferometric modulator. A thin film material is deposited over an interferometric modulator and transparent substrate to encapsulate the interferometric modulator. A gap or cavity between the interferometric modulator and the thin film provides a space in which mechanical parts of the interferometric modulator may move. The gap is created by removal of a sacrificial layer that is deposited over the interferometric modulator.
    Type: Application
    Filed: September 13, 2011
    Publication date: January 5, 2012
    Applicant: QUALCOMM MEMS TECHNOLOGIES, INC.
    Inventors: Lauren Palmateer, William J. Cummings, Brian Gally, Mark Miles, Jeffrey B. Sampsell, Clarence Chui, Manish Kothari
  • Patent number: 8045835
    Abstract: A package structure and method of packaging for an interferometric modulator. A thin film material is deposited over an interferometric modulator and transparent substrate to encapsulate the interferometric modulator. A gap or cavity between the interferometric modulator and the thin film provides a space in which mechanical parts of the interferometric modulator may move. The gap is created by removal of a sacrificial layer that is deposited over the interferometric modulator.
    Type: Grant
    Filed: August 15, 2008
    Date of Patent: October 25, 2011
    Assignee: QUALCOMM MEMS Technologies, Inc.
    Inventors: Lauren Palmateer, William J. Cummings, Brian Gally, Mark Miles, Jeffrey B. Sampsell, Clarence Chui, Manish Kothari
  • Publication number: 20090059342
    Abstract: A package structure and method of packaging for an interferometric modulator. A thin film material is deposited over an interferometric modulator and transparent substrate to encapsulate the interferometric modulator. A gap or cavity between the interferometric modulator and the thin film provides a space in which mechanical parts of the interferometric modulator may move. The gap is created by removal of a sacrificial layer that is deposited over the interferometric modulator.
    Type: Application
    Filed: August 15, 2008
    Publication date: March 5, 2009
    Applicant: IDC, LLC
    Inventors: Lauren Palmateer, William J. Cummings, Brian Gally, Mark Miles, Jeffrey B. Sampsell, Clarence Chui, Manish Kothari
  • Patent number: 7424198
    Abstract: A package structure and method of packaging for an interferometric modulator. A thin film material is deposited over an interferometric modulator and transparent substrate to encapsulate the interferometric modulator. A gap or cavity between the interferometric modulator and the thin film provides a space in which mechanical parts of the interferometric modulator may move. The gap is created by removal of a sacrificial layer that is deposited over the interferometric modulator.
    Type: Grant
    Filed: January 28, 2005
    Date of Patent: September 9, 2008
    Assignee: IDC, LLC
    Inventors: Lauren Palmateer, William J. Cummings, Brian Gally, Mark Miles, Jeffrey B. Sampsell, Clarence Chui, Manish Kothari
  • Publication number: 20080106782
    Abstract: Light in the visible spectrum is modulated using an array of modulation elements, and control circuitry connected to the array for controlling each of the modulation elements independently, each of the modulation elements having a surface which is caused to exhibit a predetermined impedance characteristic to particular frequencies of light. The amplitude of light delivered by each of the modulation elements is controlled independently by pulse code modulation. Each modulation element has a deformable portion held under tensile stress, and the control circuitry controls the deformation of the deformable portion. Each deformable element has a deformation mechanism and an optical portion, the deformation mechanism and the optical portion independently imparting to the element respectively a controlled deformation characteristic and a controlled modulation characteristic. The deformable modulation element may be a non-metal.
    Type: Application
    Filed: August 20, 2007
    Publication date: May 8, 2008
    Applicant: IDC, LLC
    Inventor: Mark Miles
  • Publication number: 20080088911
    Abstract: Light in the visible spectrum is modulated using an array of modulation elements, and control circuitry connected to the array for controlling each of the modulation elements independently, each of the modulation elements having a surface which is caused to exhibit a predetermined impedance characteristic to particular frequencies of light. The amplitude of light delivered by each of the modulation elements is controlled independently by pulse code modulation. Each modulation element has a deformable portion held under tensile stress, and the control circuitry controls the deformation of the deformable portion. Each deformable element has a deformation mechanism and an optical portion, the deformation mechanism and the optical portion independently imparting to the element respectively a controlled deformation characteristic and a controlled modulation characteristic. The deformable modulation element may be a non-metal.
    Type: Application
    Filed: August 20, 2007
    Publication date: April 17, 2008
    Applicant: IDC, LLC
    Inventor: Mark Miles
  • Publication number: 20080088908
    Abstract: Light in the visible spectrum is modulated using an array of modulation elements, and control circuitry connected to the array for controlling each of the modulation elements independently, each of the modulation elements having a surface which is caused to exhibit a predetermined impedance characteristic to particular frequencies of light. The amplitude of light delivered by each of the modulation elements is controlled independently by pulse code modulation. Each modulation element has a deformable portion held under tensile stress, and the control circuitry controls the deformation of the deformable portion. Each deformable element has a deformation mechanism and an optical portion, the deformation mechanism and the optical portion independently imparting to the element respectively a controlled deformation characteristic and a controlled modulation characteristic. The deformable modulation element may be a non-metal.
    Type: Application
    Filed: August 20, 2007
    Publication date: April 17, 2008
    Applicant: IDC, LLC
    Inventor: Mark Miles
  • Publication number: 20080088910
    Abstract: Light in the visible spectrum is modulated using an array of modulation elements, and control circuitry connected to the array for controlling each of the modulation elements independently, each of the modulation elements having a surface which is caused to exhibit a predetermined impedance characteristic to particular frequencies of light. The amplitude of light delivered by each of the modulation elements is controlled independently by pulse code modulation. Each modulation element has a deformable portion held under tensile stress, and the control circuitry controls the deformation of the deformable portion. Each deformable element has a deformation mechanism and an optical portion, the deformation mechanism and the optical portion independently imparting to the element respectively a controlled deformation characteristic and a controlled modulation characteristic. The deformable modulation element may be a non-metal.
    Type: Application
    Filed: August 20, 2007
    Publication date: April 17, 2008
    Applicant: IDC, LLC
    Inventor: Mark Miles
  • Publication number: 20080088904
    Abstract: Light in the visible spectrum is modulated using an array of modulation elements, and control circuitry connected to the array for controlling each of the modulation elements independently, each of the modulation elements having a surface which is caused to exhibit a predetermined impedance characteristic to particular frequencies of light. The amplitude of light delivered by each of the modulation elements is controlled independently by pulse code modulation. Each modulation element has a deformable portion held under tensile stress, and the control circuitry controls the deformation of the deformable portion. Each deformable element has a deformation mechanism and an optical portion, the deformation mechanism and the optical portion independently imparting to the element respectively a controlled deformation characteristic and a controlled modulation characteristic. The deformable modulation element may be a non-metal.
    Type: Application
    Filed: August 20, 2007
    Publication date: April 17, 2008
    Applicant: IDC, LLC
    Inventor: Mark Miles