Patents by Inventor Mark Nixon

Mark Nixon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 11499973
    Abstract: Methods of predicting responsiveness of a cancer in a subject to a cancer therapy including a VEGF targeting agent are provided. The methods may include obtaining a sample from the subject, determining an expression level of at least one biomarker selected from the group consisting of VEGF-D and PlGF in a sample from the subject, comparing the expression level of the biomarker in the sample to a reference level of the biomarker, and predicting the responsiveness of the cancer to treatment with the cancer therapy including a VEGF targeting agent. Optionally, the methods may further include administering a VEGF target agent and/or an anticancer or chemotherapy agent to the subject. Additional methods of prognosing and treating a cancer in a subject are also provided.
    Type: Grant
    Filed: May 17, 2017
    Date of Patent: November 15, 2022
    Assignee: Duke University
    Inventors: Andrew Nixon, Chris Brady, Yingmiao Liu, Herbert Hurwitz, Kouros Owzar, Alexander Sibley, Chen Jiang, Ace Hatch, Mark Starr
  • Publication number: 20220260961
    Abstract: Methods and apparatus to virtualize a process control system are described. A described process control system includes a server cluster including one or more servers. When operating, the server cluster provides a virtual workstation or virtual server, a virtual controller to interoperate with the virtual workstation or server and to implement process control operations, and a virtual input/output device to interoperate with the virtual controller and coupled to one or more field devices within the process control system.
    Type: Application
    Filed: May 2, 2022
    Publication date: August 18, 2022
    Inventors: Mark Nixon, John Mark Caldwell
  • Patent number: 11407564
    Abstract: The present application is directed to cap assemblies and particularly, cap assembly for closing an opening in a vessel, the cap assembly including a stopper including an polymer body adapted to fit an opening of a vessel, the stopper also including a tubular portion which defines an internal passageway extending through the polymer body; and a rigid cap attached to and integral with the stopper, wherein the cap is adapted to engage the vessel and provide a sealing force between the stopper and the vessel.
    Type: Grant
    Filed: November 30, 2017
    Date of Patent: August 9, 2022
    Assignee: SAINT-GOBAIN PERFORMANCE PLASTICS CORPORATION
    Inventors: Gerald Mark Pennington, Khoa D. Pham, Thomas R. Nixon, Christopher Miller
  • Patent number: 11320797
    Abstract: Methods and apparatus to virtualize a process control system are described. A described process control system includes a server cluster including one or more servers. When operating, the server cluster provides a virtual workstation or virtual server, a virtual controller to interoperate with the virtual workstation or server and to implement process control operations, and a virtual input/output device to interoperate with the virtual controller and coupled to one or more field devices within the process control system.
    Type: Grant
    Filed: September 27, 2011
    Date of Patent: May 3, 2022
    Assignee: FISHER-ROSEMOUNT SYSTEMS, INC
    Inventors: Mark Nixon, John Mark Caldwell
  • Patent number: 10574791
    Abstract: Example methods and apparatus to access process data stored on a server are described herein. An example method includes receiving a request to access process data via a web browser, identifying a server that stores at least a portion of the process data, wherein the server is associated with an interoperability data packing format, accessing the server to receive the process data, converting the process data from a format associated with the interoperability data packing format to a web browsing format, and embedding at least a first portion of the converted process data into at least one data field for display via the web browser.
    Type: Grant
    Filed: July 20, 2015
    Date of Patent: February 25, 2020
    Assignee: Fisher-Rosemount Systems, INC.
    Inventors: Lee Allen Neitzel, Ling Zhou, Mark Nixon
  • Patent number: 10083249
    Abstract: Systems, methods, and articles of manufacture to provide a search service to users of a process control system are disclosed. An example system includes a search database to store a set of searchable items associated with a process control system and to store a search profile associated with a selected query result, a publisher to collect information associated with the searchable items from the process control system and to publish the collected information to the search database, and a searcher to receive a request including the search profile and a query of the searchable items in the database, to search the searchable items based on the query, and to return at least a portion of the collected information based on the search profile.
    Type: Grant
    Filed: September 23, 2010
    Date of Patent: September 25, 2018
    Assignee: FISHER-ROSEMOUNT SYSTEMS, INC.
    Inventors: Mark Nixon, Eric Rotvold, Jeff Potter
  • Patent number: 9983575
    Abstract: Systems and methods to graphically display process control system information are disclosed. Some example methods include monitoring process variables in a process control system, determining a current state of a first one of the process variables, and determining a trend associated with the first process variable. Some such examples further include generating a first graphic representative of information associated with the first process variable, the information comprising the current state of the first process variable and the trend of the first process variable. Some example methods also include rendering the first graphic via a display.
    Type: Grant
    Filed: April 9, 2013
    Date of Patent: May 29, 2018
    Assignee: FISHER-ROSEMOUNT SYSTEMS, INC.
    Inventors: Mark Nixon, Maia B. Cook, Daniel I. Manes, Harvey S. Smallman
  • Patent number: 9904263
    Abstract: Smart process objects, which have both graphical and simulation elements, may be used to create one or more graphic displays and one or more process simulation modules, each having elements which may communicate with one another and with devices within a process plant to model and depict the operation of a process plant. The smart process objects may include one or more device objects, which represent physical devices within the process plant, and may include one or more smart connection objects which represent and model the flow of a material, such as a gas, a liquid, a composition of solid, electricity, etc., through a connection between entities within the process plant. The smart process objects may also include one or more smart stream objects, which also may represent and model the flow of a material at a particular point in the process plant.
    Type: Grant
    Filed: December 16, 2004
    Date of Patent: February 27, 2018
    Assignee: FISHER-ROSEMOUNT SYSTEMS, INC.
    Inventors: Terrence Blevins, Mark Nixon, Michael Lucas, Arthur Webb, Ken Beoughter
  • Patent number: 9874870
    Abstract: Example methods and apparatus to manage testing of a process control system are disclosed. A disclosed example method includes generating a test application from a process control routine, the test application including at least one test that is to be performed within a time period, monitoring an operation of the process control routine, determining if the operation of the process control routine during the time period includes an execution of a portion of the process control routine that is substantially similar to the at least one test, and updating the test application by indicating that the at least one test has been performed within the time period.
    Type: Grant
    Filed: August 26, 2009
    Date of Patent: January 23, 2018
    Assignee: Fisher-Rosemount Systems, Inc.
    Inventors: Gary Keith Law, Godfrey R. Sherriff, Mark Nixon
  • Publication number: 20170300024
    Abstract: Methods and apparatus to virtualize a process control system are described. A described process control system includes a server cluster including one or more servers. When operating, the server cluster provides a virtual workstation or virtual server, a virtual controller to interoperate with the virtual workstation or server and to implement process control operations, and a virtual input/output device to interoperate with the virtual controller and coupled to one or more field devices within the process control system.
    Type: Application
    Filed: September 27, 2011
    Publication date: October 19, 2017
    Inventors: Mark Nixon, John Mark Caldwell
  • Patent number: 9483352
    Abstract: Process control system and methods are disclosed. An example method includes operating a first cluster including first virtual machines and first servers and operating a second cluster including second virtual machines and second servers. The example method also includes storing first data from the first virtual machines at a first data store of the first cluster and storing a replica of the first data at a second data store of the second cluster. The example method also includes storing second data from the second virtual machines at the second data store and storing a replica of the second data at the first data store and identifying a failure of the first cluster. The method also includes, in response to the failure, restarting the first virtual machines using the second servers and the replica of the first data at the second data store.
    Type: Grant
    Filed: September 23, 2014
    Date of Patent: November 1, 2016
    Assignee: FISHER-ROSEMONT SYSTEMS, INC.
    Inventors: Dirk Thiele, Shaobo Qiu, Mark Nixon
  • Patent number: 9354629
    Abstract: Example methods and apparatus to configure a process control system using an electronic description language (EDL) script are disclosed. A disclosed example method comprises loading a first script representative of a process plant, the first script comprising an interpretive system-level script structured in accordance with an electronic description language, and compiling the first script to form a second script, the second script structured in accordance with a vendor-specific configuration language associated with a particular process control system for the process plant.
    Type: Grant
    Filed: February 19, 2009
    Date of Patent: May 31, 2016
    Assignee: Fisher-Rosemount Systems, Inc.
    Inventors: James Randall Balentine, Gary Keith Law, Mark Nixon
  • Publication number: 20160050295
    Abstract: Example methods and apparatus to access process data stored on a server are described herein. An example method includes receiving a request to access process data via a web browser, identifying a server that stores at least a portion of the process data, wherein the server is associated with an interoperability data packing format, accessing the server to receive the process data, converting the process data from a format associated with the interoperability data packing format to a web browsing format, and embedding at least a first portion of the converted process data into at least one data field for display via the web browser.
    Type: Application
    Filed: July 20, 2015
    Publication date: February 18, 2016
    Inventors: Lee Allen Neitzel, Ling Zhou, Mark Nixon
  • Patent number: 9229947
    Abstract: Example methods and apparatus to manage process control data are disclosed. A disclosed example method includes receiving a request for process data associated with a field device, searching a database for a descriptor file that includes the requested process data, and accessing the descriptor file to retrieve the process data to display within an application, wherein the process data is retrieved using a schema that specifies that the process data is located at an object referenced by a file entry that is part of a section of a file body included within the file. In the example method, the object may include at least one of an expression to calculate a value using the process data in a mathematical formula or a display transformation to instruct how the process data is to be displayed.
    Type: Grant
    Filed: September 27, 2010
    Date of Patent: January 5, 2016
    Assignee: Fisher-Rosemount Systems, Inc.
    Inventor: Mark Nixon
  • Patent number: 9207666
    Abstract: Example methods and apparatus to display localized process control objects. A disclosed example method includes receiving a request to view a process control object associated with a process control system, selecting a device description file based on the process control object, the device description file including a tag, selecting a set of locale templates based on a locale associated with the request, selecting a locale template from the set of locale templates based on the process control object, and processing the process control object for display by inserting portions of the selected locale template into the tag in the device description file.
    Type: Grant
    Filed: August 31, 2010
    Date of Patent: December 8, 2015
    Assignee: Fisher-Rosemount Systems, Inc.
    Inventors: Mark Nixon, Lee Allen Neitzel, Ling Zhou
  • Patent number: 9158295
    Abstract: A process is modeled by resolving the process into a plurality of process stages, including at least a first process stage and a second process stage, and developing a plurality of models, each model corresponding to a respective one of the plurality of process stages, wherein the model corresponding to each process stage is developed using data from one or more runs of that process stage and output quality data relating to the one or more runs of that process stage and wherein the model corresponding to each process stage is adapted to produce an output quality prediction associated with that process stage, and wherein the output quality prediction produced by the model of a first one of the process stages is used to develop the model of a second one of the process stages.
    Type: Grant
    Filed: May 21, 2011
    Date of Patent: October 13, 2015
    Assignee: FISHER-ROSEMOUNT SYSTEMS, INC.
    Inventors: Terrence L. Blevins, Wilhelm K. Wojsznis, Christopher J. Worek, Mark Nixon
  • Patent number: 9122764
    Abstract: Example methods and apparatus to access process data stored on a server are disclosed. A disclosed example method includes receiving a request to access process data via a web browser, identifying a server that stores at least a portion of the process data, wherein the server is associated with an interoperability data packing format, accessing the server to receive the process data, converting the process data from a format associated with the interoperability data packing format to a web browsing format, and embedding at least a first portion of the converted process data into at least one data field for display via the web browser.
    Type: Grant
    Filed: March 24, 2010
    Date of Patent: September 1, 2015
    Assignee: Fisher-Rosemount Systems, Inc.
    Inventors: Lee Allen Neitzel, Ling Zhou, Mark Nixon
  • Patent number: 9069344
    Abstract: An operator interface within a process plant includes an execution engine that implements process flow modules made up of interconnected smart process objects that are aware of devices and other entities within the plant and that can perform methods to detect conditions within the plant, especially on a system-level basis. The smart process objects include a display element to be displayed to the operator, data storage for storing data pertaining to and/or received from an associated entity within a plant, inputs and outputs for communicating with other smart process objects and methods that may be executed on the stored and received data to detect plant conditions, including system-level conditions, such as leaks, errors and other conditions. Process flow modules, which may be made up of numerous interconnected smart process objects, may also include flow algorithms associated therewith to calculate mass balances, flows, etc. for the process elements within the process flow modules.
    Type: Grant
    Filed: December 5, 2006
    Date of Patent: June 30, 2015
    Assignee: FISHER-ROSEMOUNT SYSTEMS, INC.
    Inventors: Duncan Schleiss, Ram Ramachandran, Mark Nixon, Michael Lucas
  • Publication number: 20150095692
    Abstract: Process control system and methods are disclosed. An example method includes operating a first cluster including first virtual machines and first servers and operating a second cluster including second virtual machines and second servers. The example method also includes storing first data from the first virtual machines at a first data store of the first cluster and storing a replica of the first data at a second data store of the second cluster. The example method also includes storing second data from the second virtual machines at the second data store and storing a replica of the second data at the first data store and identifying a failure of the first cluster. The method also includes, in response to the failure, restarting the first virtual machines using the second servers and the replica of the first data at the second data store.
    Type: Application
    Filed: September 23, 2014
    Publication date: April 2, 2015
    Inventors: Dirk Thiele, Shaobo Qiu, Mark Nixon
  • Patent number: 8908666
    Abstract: A communication method operates to seamlessly transmit internet protocol (IP) data frames, such as IPv6 data frames, over a communication network that uses a non-IP network routing protocol, i.e., a communication network that implements a network routing protocol other than, or that is incompatible with an IP network routing protocol, such as the WirelessHART protocol. This communication method enables, for example, field devices or other intelligent devices within a process plant network that uses a non-IP communication network to perform messaging of IP data frames generated at or to be received by internet protocol enabled devices either within the process plant network or outside of the process plant network.
    Type: Grant
    Filed: September 14, 2012
    Date of Patent: December 9, 2014
    Assignee: Fisher-Rosemount Systems, Inc.
    Inventors: Mark Nixon, Song Han, Eric Rotvold, Deji Chen