Patents by Inventor Mark Olavesen

Mark Olavesen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CORNEODESMOSIN BASED TEST AND MODEL FOR INFLAMMATORY DISEASE
    Publication number: 20080193939
    Abstract: The present invention relates to a polynucleotide encoding the corneodesmosin protein having one or more nucleotide insertions, deletions, or substitutions at one or more novel positions. The invention also relates to the corneodesmosin protein having one or more amino acid insertions, deletions, and substitutions. These nucleotide and amino acid polymorphisms are useful in diagnosing or determining susceptibility to corneodesmosin-mediated disease, such as inflammatory diseases, including psoriasis, and in treating such disease. Host cells and transgenic non-human animals comprising polynucleotides or proteins of the invention are provided. Methods of screening for agents for use in treating corneodesmosin-mediated disease are also provided.
    Type: Application
    Filed: November 29, 2007
    Publication date: August 14, 2008
    Applicant: YORK PHARMA (R & D) LIMITED
    Inventors: Mark Olavesen, Nick Lench, Maxine Allen, Rachid Tazi-Ahnini
  • Corneodesmosin based test and model for inflammatory disease
    Patent number: 7329540
    Abstract: The present invention relates to a polynucleotide encoding the corneodesmosin protein having one or more nucleotide insertions, deletions or substitutions at one or novel positions. The invention also relates to the corneodesmosin protein having one or more amino acid insertions, deletions and substitutions. These nucleotide and amino acid polymorphisms are useful in diagnosing or determining susceptibility to corneodesmosin-mediated disease, for example inflammatory diseases including psoriasis, and in treating such disease. Host cells and transgenic non-human animals comprising polynucleotides or proteins of the invention are provided. Methods of screening for agents for use in treating corneodesmosin-mediated disease are also provided.
    Type: Grant
    Filed: February 23, 2001
    Date of Patent: February 12, 2008
    Assignee: York Pharma (R & D) Limited
    Inventors: Mark Olavesen, Nick Lench, Maxine Allen, Rachind Tazi-Ahnini
  • Corneodesmosin based test and model for inflammatory disease
    Publication number: 20030186371
    Abstract: The present invention relates to a polynucleotide encoding the corneodesmosin protein having one or more nucleotide insertions, deletions or substitutions at one or novel positions. The invention also relates to the corneodesmosin protein having one or more amino acid insertions, deletions and substitutions. These nucleotide and amino acid polymorphisms are useful in diagnosing or determining susceptibility to corneodesmosin-mediated disease, for example inflammatory diseases including psoriasis, and in treating such disease. Host cells and transgenic non-human animals comprising polynucleotides or proteins of the invention are provided. Methods of screening for agents for use in treating corneodesmosin-mediated disease are also provided.
    Type: Application
    Filed: January 29, 2003
    Publication date: October 2, 2003
    Inventors: Mark Olavesen, Nick Lench, Maxine Allen, Rachid Tazi-Ahnini