Abstract: This disclosure describes a rapid, high throughput, facile testing platform. Amplified DNA and CRISPR/Cas9-bound products are analyzed via a lateral flow assay (LFA), and the assay does not require specialized infrastructure. In some embodiments, the testing platform may be used to detect SARS-CoV-2, including, for example, as a test for COVID-19.

Abstract: The invention is directed to transcription activator-like effector nuclease (TALEN)-mediated DNA editing of disease-causing mutations in the context of the human genome and human cells to treat patients with compromised genetic disorders.

Abstract: The invention is directed to transcription activator-like effector nuclease (TALEN)-mediated DNA editing of disease-causing mutations in the context of the human genome and human cells to treat patients with compromised genetic disorders.

Abstract: The invention is directed to transcription activator-like effector nuclease (TALEN)-mediated DNA editing of disease-causing mutations in the context of the human genome and human cells to treat patients with compromised genetic disorders.

Abstract: The invention is directed to transcription activator-like effector nuclease (TALEN)-mediated DNA editing of disease-causing mutations in the context of the human genome and human cells to treat patients with compromised genetic disorders.

Abstract: The invention is directed to transcription activator-like effector nuclease (TALEN)-mediated DNA editing of disease-causing mutations in the context of the human genome and human cells to treat patients with compromised genetic disorders.

Abstract: A tray assembly has a tray and a divider assembly removably connected to the tray. The tray has a base, a first side fixedly attached to the base, a second side fixedly attached to the base and the first side, a third side opposite the first side and fixedly attached to the base and the second side, and a fourth side opposite the second side and pivotally connected to the base.

Abstract: A method for diagnosing and classifying faults in a system is provided. The method comprises acquiring operational data for at least one of a system, one or more subsystems of the system or one or more components of the one or more subsystems. Then, the method comprises analyzing the operational data using one or more diagnostic models. Each diagnostic model uses the operational data to determine a probability of fault associated with at least one of the one or more components or the one or more subsystems. Finally, the method comprises deriving an overall probability of fault for at least one of the system, the one or more subsystems, or the one or more components using the one or more probabilities of fault determined by the one or more diagnostic models and one or more hierarchical relationships between the subsystems and components of the system.

Abstract: A rectifier assembly includes individual diodes arranged to form a full-wave bridge such that the silicon wafers of the diodes are loaded in compression. As so arranged, the centrifugal forces add to the compression forces on the diodes and on the electrical contacts therewith. The three-phase (AC) input conductors are connected by conductive straps which connect the diodes through to DC (+/?) terminal ring outputs. One surface of each of the diodes is in electrical contact with a conductive strap which then connects with the individual (AC) phases of an exciter rotor winding. The opposing surface of the diode contacts the ring diode pad on either the DC (+/?) output terminal ring. Two conductive posts, each of which are connected to only one of the DC (+/?) output terminal rings permit external connection to a main rotor winding.

Abstract: The present invention is a rectifier assembly having three phase straps with two diodes mounted to each phase strap. The rectifier assembly also includes a first support and a second support, which are received within a housing. The phase straps are assembled together with the first and second supports. The diodes are each connected to the phase straps so that when assembled the diodes are each perpendicular to an axis at the center of the electrically insulated housing. During operation the first and second supports rotate about the axis.

Abstract: A method for predicting a time to failure of a component in a system is presented. The method comprises obtaining a set of data measurements related to the component. The set of data measurements are representative of a plurality of parameters including a plurality of leading parameters. The method comprises generating a prediction model based upon the leading parameters considered in combination. The prediction model is then used to predict the time to failure of the component based on a set of real-time measurements, wherein the plurality of parameters are processed to predict the time to failure for the component. Finally, a confidence level for the predicted time to failure is determined based upon the plurality of parameters.

Abstract: A technique is disclosed for evaluating and monitoring performance of a heat exchanger system. Operating parameters of the system are monitored and fouling factors for heat transfer surfaces of the exchanger are determined. Trending of fouling may be performed over time based upon the fouling factors, and a model of fouling may be selected from known sets of models, or a model may be developed or refined. Fluid treatment, such as water treatment regimes may be taken into account in evaluation of fouling. An automated knowledge based analysis algorithm may diagnose possible caused of fouling based upon sensed and observed parameters and conditions. Corrective actions may be suggested and the system controlled to reduce, avoid or correct for detected fouling.

Abstract: A tray assembly has a tray and a divider assembly removably connected to the tray. The tray has a base, a first side fixedly attached to the base, a second side fixedly attached to the base and the first side, a third side opposite the first side and fixedly attached to the base and the second side, and a fourth side opposite the second side and pivotally connected to the base.