Patents by Inventor Mark P. McPike

Mark P. McPike has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Library compositions and methods for acyclic identification of aptamers
    Patent number: 9193968
    Abstract: The present invention provides improved aptamer libraries useful for discovery of aptamers that have high binding affinity for a single or a plurality of targets. The libraries contain higher copies of each member candidate such that they are more likely to be available to the application of acyclic identification methods that obviate the most time-consuming and costly step in traditional SELEX method, the multiple cycles of evolutionary selection.
    Type: Grant
    Filed: March 1, 2011
    Date of Patent: November 24, 2015
    Assignee: APTAMATRIX, INC.
    Inventors: Philip N. Borer, Mark P. McPike
  • Library Compositions and Methods for Acyclic Identification of Aptamers
    Publication number: 20150259673
    Abstract: The present invention provides improved aptamer libraries useful for discovery of aptamers that have high binding affinity for a single or a plurality of targets. The libraries contain higher copies of each member candidate such that they are more likely to be available to the application of acyclic identification methods that obviate the most time-consuming and costly step in traditional SELEX method, the multiple cycles of evolutionary selection.
    Type: Application
    Filed: March 1, 2011
    Publication date: September 17, 2015
    Inventors: Philip N. Borer, Mark P. McPike
  • Library Compositions and Methods for Acyclic Identification of Aptamers
    Publication number: 20130217582
    Abstract: The present invention provides improved aptamer libraries useful for discovery of aptamers that have high binding affinity for a single or a plurality of targets. The libraries contain higher copies of each member candidate such that they are more likely to be available to the application of acyclic identification methods that obviate the most time-consuming and costly step in traditional SELEX method, the multiple cycles of evolutionary selection.
    Type: Application
    Filed: March 1, 2011
    Publication date: August 22, 2013
    Inventors: Philip N. Borer, Mark P. McPike
  • DIRECT SELECTION OF STRUCTURALLY DEFINED APTAMERS
    Publication number: 20110263459
    Abstract: The present invention provides aptamer libraries with pre-defined secondary structures that can be used for oversampled screening for affinity binding.
    Type: Application
    Filed: March 12, 2009
    Publication date: October 27, 2011
    Inventors: Philip N. Borer, Mark P. McPike