Patents by Inventor Mark P. Roach

Mark P. Roach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Antisense modulation of phosphodiesterase 4D expression
    Publication number: 20030220273
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of phosphodiesterase 4D. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding phosphodiesterase 4D. Methods of using these compounds for modulation of phosphodiesterase 4D expression and for treatment of diseases associated with expression of phosphodiesterase 4D are provided.
    Type: Application
    Filed: May 15, 2002
    Publication date: November 27, 2003
    Applicant: Isis Pharmaceuticals Inc.
    Inventors: C. Frank Bennett, Kenneth W. Dobie, Mark P. Roach
  • Antisense modulation of estrogen receptor alpha expression
    Publication number: 20030211611
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of estrogen receptor alpha. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding estrogen receptor alpha. Methods of using these compounds for modulation of estrogen receptor alpha expression and for treatment of diseases associated with expression of estrogen receptor alpha are provided.
    Type: Application
    Filed: May 30, 2003
    Publication date: November 13, 2003
    Inventors: Kenneth W. Dobie, Mark P. Roach
  • Antisense modulation of estrogen receptor alpha expression
    Patent number: 6617162
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of estrogen receptor alpha. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding estrogen receptor alpha. Methods of using these compounds for modulation of estrogen receptor alpha expression and for treatment of diseases associated with expression of estrogen receptor alpha are provided.
    Type: Grant
    Filed: December 18, 2001
    Date of Patent: September 9, 2003
    Assignee: ISIS Pharmaceuticals, Inc.
    Inventors: Kenneth W. Dobie, Mark P. Roach
  • Antisense modulation of estrogen receptor beta expression
    Publication number: 20030158144
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of estrogen receptor beta. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding estrogen receptor beta. Methods of using these compounds for modulation of estrogen receptor beta expression and for treatment of diseases associated with expression of estrogen receptor beta are provided.
    Type: Application
    Filed: February 27, 2003
    Publication date: August 21, 2003
    Inventors: Kenneth W. Dobie, Mark P. Roach, Erich Koller
  • ANTISENSE MODULATION OF ESTROGEN RECEPTOR ALPHA EXPRESSION
    Publication number: 20030139360
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of estrogen receptor alpha. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding estrogen receptor alpha. Methods of using these compounds for modulation of estrogen receptor alpha expression and for treatment of diseases associated with expression of estrogen receptor alpha are provided.
    Type: Application
    Filed: December 18, 2001
    Publication date: July 24, 2003
    Applicant: Isis Pharmaceuticals Inc.
    Inventors: Kenneth W. Dobie, Mark P. Roach
  • Antisense modulation of PCTAIRE protein kinase 1 expression
    Publication number: 20030138952
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of PCTAIRE protein kinase 1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding PCTAIRE protein kinase 1. Methods of using these compounds for modulation of PCTAIRE protein kinase 1 expression and for treatment of diseases associated with expression of PCTAIRE protein kinase 1 are provided.
    Type: Application
    Filed: December 7, 2001
    Publication date: July 24, 2003
    Applicant: Isis Pharmaceuticals Inc.
    Inventors: Susan M. Freier, Mark P. Roach
  • Antisense modulation of vitamin D nuclear receptor expression
    Publication number: 20030125271
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of vitamin D nuclear receptor. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding vitamin D nuclear receptor. Methods are provided for using these compounds for modulation of vitamin D nuclear receptor expression, including examples of modulation of specific variants of vitamin D nuclear receptor relative to other variants. Methods for treatment of diseases associated with expression of vitamin D nuclear receptor are provided.
    Type: Application
    Filed: November 14, 2001
    Publication date: July 3, 2003
    Applicant: Isis Pharmaceuticals Inc.
    Inventors: Brenda F. Baker, Kenneth Dobie, Mark P. Roach
  • Antisense modulation of NOD1 expression
    Publication number: 20030119767
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of NOD1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding NOD1. Methods of using these compounds for modulation of NOD1 expression and for treatment of diseases associated with expression of NOD1 are provided.
    Type: Application
    Filed: December 5, 2001
    Publication date: June 26, 2003
    Applicant: Isis Pharmaceuticals Inc.
    Inventors: Kenneth W. Dobie, Mark P. Roach