Patents by Inventor Mark P. Sweet

Mark P. Sweet has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Rigid bifunctional chelating agents
    Patent number: 6022522
    Abstract: Bicyclo[2.2.2]octane-2,3 diamine-N,N,N',N'-tetraacetic acids (BODTA) and bicyclo[2.2.1]heptane-2,3 diamine-N,N,N',N'-tetraacetic acid (BHDTA) are chelating agents useful in forming detectably labeled bioconjugate compounds for diagnostic and therapeutic purposes. New compounds and processes of forming BODTA and BHDTA are disclosed. Radioimmunoconjugates of the present invention show high and prolonged tumor uptake with low normal tissue uptakes.
    Type: Grant
    Filed: March 23, 1998
    Date of Patent: February 8, 2000
    Assignee: Brookhaven Science Associates
    Inventors: Mark P. Sweet, Ronnie C. Mease, Suresh C. Srivastava
  • Rigid bifunctional chelating agents
    Patent number: 5783169
    Abstract: Bicyclo?2.2.2! octane-2,3 diamine-N,N,N',N'-tetraacetic acids (BODTA) and bicyclo?2.2.1! heptane-2,3 diamine-N,N,N',N'-tetraacetic acid (BHDTA) are chelating agents useful in forming detectably labeled bioconjugate compounds for diagnostic and therapeutic purposes. New compounds and processes of forming BODTA and BHDTA are disclosed. Radioimmunoconjugates of the present invention show high and prolonged tumor uptake with low normal tissue uptakes.
    Type: Grant
    Filed: July 26, 1995
    Date of Patent: July 21, 1998
    Assignee: Brookhaven Science Associates LLC
    Inventors: Mark P. Sweet, Ronnie C. Mease, Suresh C. Srivastava