Abstract: A system and method for identifying over sedation risk factors and generating appropriate alerts for healthcare professionals as a result of an algorithm triggered based whether a calculated over sedation risk score/level for the patient crosses a predefined threshold, and determine whether the patient score is at a low, moderate, or high risk for over sedation. If the patient is at a moderate or high risk, an alert may be triggered and displayed to the healthcare professional, along with data associated with the alert in a synchronized timeline displayed on a user interface.

Abstract: This disclosure relates to detecting prostate cancer. A processor receives image data indicative of a computed tomography scan comprising a spatial sequence of two-dimensional cross-sectional images. The processor then applies a neural network to the image data by calculating three-dimensional convolutions in one or more convolutional layers of the neural network and evaluating an output layer. A first dimension of the convolutions is defined in space along the spatial sequence of the two-dimensional cross-sectional images. The three-dimensional convolutions comprise convolutions along the first dimension. The output layer is connected to the one or more convolutional layers in the neural network, and has an output value that is indicative of a probability of detecting prostate cancer in the computed tomography scan. Three-dimensional convolutions in the neural network provide a more accurate probability of detecting prostate cancer.

Abstract: An electric vertical takeoff and landing aircraft including a teetering propulsor assembly is provided. Teetering propulsor assembly may include a propeller that includes a hub and blades. Hub of propeller may be mechanically connected to a teeter mechanism of propulsor assembly that may be configured to allow the propeller to pivot about a teeter axis relative to the electric aircraft. Thus, teeter mechanism allows for a rotational axis of propeller to move during teetering of propeller. Teeter mechanism may include one or more springs that reduce teetering or prevent teetering of the propulsor at certain rotational speeds of propeller.

Abstract: This disclosure relates to detecting prostate cancer. A processor receives image data indicative of a computed tomography scan comprising a spatial sequence of two-dimensional cross-sectional images. The processor then applies a neural network to the image data by calculating three-dimensional convolutions in one or more convolutional layers of the neural network and evaluating an output layer. A first dimension of the convolutions is defined in space along the spatial sequence of the two-dimensional cross-sectional images. The three-dimensional convolutions comprise convolutions along the first dimension. The output layer is connected to the one or more convolutional layers in the neural network, and has an output value that is indicative of a probability of detecting prostate cancer in the computed tomography scan. Three-dimensional convolutions in the neural network provide a more accurate probability of detecting prostate cancer.

Abstract: Various embodiments of a predictive double-booking system for use in medical appointment booking applications are described herein.

Abstract: An electric vertical takeoff and landing aircraft including a teetering propulsor assembly is provided. Teetering propulsor assembly may include a propeller that includes a hub and blades. Hub of propeller may be mechanically connected to a teeter mechanism of propulsor assembly that may be configured to allow the propeller to pivot about a teeter axis relative to the electric aircraft. Thus, teeter mechanism allows for a rotational axis of propeller to move during teetering of propeller. Teeter mechanism may include one or more springs that reduce teetering or prevent teetering of the propulsor at certain rotational speeds of propeller.

Abstract: Various embodiments of a computer-implemented system for generating an algorithm configured to compute an attribution output to enhance provider attribution are disclosed.

Abstract: A system and method for identifying over sedation risk factors and generating appropriate alerts for healthcare professionals as a result of an algorithm triggered based whether a calculated over sedation risk score/level for the patient crosses a predefined threshold, and determine whether the patient score is at a low, moderate, or high risk for over sedation. If the patient is at a moderate or high risk, an alert may be triggered and displayed to the healthcare professional, along with data associated with the alert in a synchronized timeline displayed on a user interface.

Abstract: An improved luminometer, chamber insert, and deactivator is shown and described. In one embodiment, the device comprises a luminometer for use with a test sample holder and is configured to determine the emitted light from the test sample holder. Typically, the luminometer includes a housing having a sample port, a photomultiplier assembly, and a chamber having a mirrored inner side face. In certain examples, an improved chamber for a luminometer comprises an insert portion, a photomultiplier portion, and a deactivator.

Abstract: A method of treating chronic hepatitis B is disclosed that comprises administering a T cell-stimulating amount of a vaccine to a patient. The vaccine comprises an immunogenic amount of chimeric, carboxy-terminal truncated hepatitis B virus nucleocapsid (core) protein (HBc) that is engineered for both enhanced stability of self-assembled particles and the substantial absence of nucleic acid binding by those particles. The chimeric protein molecule can include one or more immunogenic epitopes peptide-bonded to one or more of the N-terminus, the immunogenic loop or the C-terminus of HBc. The enhanced stability of self-assembled particles is obtained by the presence of at least one heterologous cysteine residue near one or both of the amino-terminus and carboxy-terminus of the chimer molecule.

Abstract: A method of treating chronic hepatitis B is disclosed that comprises administering a T cell-stimulating amount of a vaccine to a patient. The vaccine comprises an immunogenic amount of chimeric, carboxy-terminal truncated hepatitis B virus nucleocapsid (core) protein (HBc) that is engineered for both enhanced stability of self-assembled particles and the substantial absence of nucleic acid binding by those particles. The chimeric protein molecule can include one or more immunogenic epitopes peptide-bonded to one or more of the N-terminus, the immunogenic loop or the C-terminus of HBc. The enhanced stability of self-assembled particles is obtained by the presence of at least one heterologous cysteine residue near one or both of the amino-terminus and carboxy-terminus of the chimer molecule.

Abstract: Methods and apparatus for docking and powering Universal Serial Bus hubs in a wagering game machine are described herein. In one embodiment, a docking Universal Serial Bus (USB) power unit includes a USB socket to receive USB data and a power socket to receive power of a first type. The USB power unit can also include a switching power unit to convert the power of the first type into power of a second type. The power unit can also include a docking connector to join the docking USB power unit to a USB hub, where the USB hub is to dock with the docking USB power unit, and where the docking connector to conduct the USB data and some of the power of the second type to the USB hub.

Abstract: The present invention provides an apparatus for dissolving a gas in a liquid, the apparatus comprising (a) a closed vessel containing a liquid at a predetermined level, (b) a contactor module at least partially immersed in the liquid having (1) a gas supply channel to the bore side of the fibers, (2) a liquid supply channel to the shell side of the fibers, and (3) an exit port for transport of a gas-containing liquid, and (c) the remaining space in the closed vessel being occupied by a pressurized gas. The liquid prepared in the apparatus of the present invention containing a dissolved gas, is used to prepare beverages, such as coffee, tea, soda, chocolate and the like, whether hot or cold.

Abstract: An improved sporting equipment shaft is provided. The present invention relates to aerodynamic drag-reducing structures. In particular, the present invention relates to a vortex splitter plate element that may be formed integrally or attached to the shaft of a sporting equipment shaft preferably a golf club shaft. The T-Blade Drag Reduction Device operates to substantially reduce turbulence produced when the sporting equipment shaft is swung through a fluid, such as air. The reduction in turbulence is reflected operationally in a faster, more powerful swing due to the lessened amount of induced aerodynamic drag. There is also a lessening of shaft vibration, which should increase swing accuracy.

Abstract: A positioning system is provided for use in a wind tunnel that results in accurate and dynamic orientation for a model while reducing aerodynamic interference. The system includes a pitch-yaw sleeve having a generally cylindrical shape and a torque tube disposed askew within the sleeve and rotatable about its longitudinal axis to drive a shaft. The shaft is generally elongated and crooked. The sting, to which a model is affixed, is rotatably attached to a distal end of the shaft. Rotation of the pitch-yaw tube and/or the pitch-yaw sleeve provides precise pitch and yaw orientation of the model, and rotation of the sting relative to the shaft provides precise roll orientation.

Abstract: The present invention provides an apparatus for dissolving a gas in a liquid, the apparatus comprising (a) a closed container containing a liquid at a predetermined level, (b) a contactor module at least partially immersed in the liquid having (1) a gas supply channel to the bore side of the fibers, (2) a liquid supply channel to the shell side of the fibers, and (3) an exit port for transport of a gas-containing liquid, and (c) the remaining space in the closed container being occupied by a pressurized gas. The liquid prepared in the apparatus of the present invention containing a dissolved gas, is used to prepare beverages, such as coffee, tea, soda, chocolate and the like, whether hot or cold.

Abstract: A positioning system is provided for use in a wind tunnel that results in accurate and dynamic orientation for a model while reducing aerodynamic interference. The system includes a pitch-yaw sleeve having a generally cylindrical shape and a torque tube disposed askew within the sleeve and rotatable about its longitudinal axis to drive a shaft. The shaft is generally elongated and crooked. The sting, to which a model is affixed, is rotatably attached to a distal end of the shaft. Rotation of the pitch-yaw tube and/or the pitch-yaw sleeve provides precise pitch and yaw orientation of the model, and rotation of the sting relative to the shaft provides precise roll orientation.

Abstract: A method of treating chronic hepatitis B is disclosed that comprises administering a T cell-stimulating amount of a vaccine to a patient. The vaccine comprises an immunogenic amount of chimeric, carboxy-terminal truncated hepatitis B virus nucleocapsid (core) protein (HBc) that is engineered for both enhanced stability of self-assembled particles and the substantial absence of nucleic acid binding by those particles. The chimeric protein molecule can include one or more immunogenic epitopes peptide-bonded to one or more of the N-terminus, the immunogenic loop or the C-terminus of HBc. The enhanced stability of self-assembled particles is obtained by the presence of at least one heterologous cysteine residue near one or both of the amino-terminus and carboxy-terminus of the chimer molecule.

Abstract: The invention provides a method for designing protein immunogen, which comprises (a) modifying the amino acid sequence of the immunogen, and (b) determining whether the T-helper (Th) cell response to the modified immunogen is of the Th1 type or the Th2 type. The method is useful in identifying immunogens for use in immunotherapy of diseases. For example, chronic hepatitis is believed to be associated with a Th2-dominated response which fails to clear the virus, and switching the Th response to a Th1 response by administration of an immunogen that induces a Th1 response may help in clearing the virus.