Abstract: Provided is an optical modulator including a substrate, and a plurality of meta units provided on the substrate and spaced apart from each other, wherein at least one of the plurality of meta units includes a metal layer provided on the substrate, a dielectric layer provided an upper surface and side surfaces of the metal layer, and an antenna provided on an upper surface of the dielectric layer, the antenna including phase change material, wherein a refractive index of the phase change material changes based on a voltage applied to the metal layer to modulate incident light.

Abstract: A method of preparing an antibody therapeutic is provided comprising: (a) providing a dissociated cell sample from at least one solid tumor sample obtained from a patient; (b) loading the dissociated cell sample into a microfluidic device having a flow region and at least one isolation region fluidically connected to the flow region; (c) moving at least one B cell from the dissociated cell sample into at least one isolation region in the microfluidic device, thereby obtaining at least one isolated B cell; and (d) using the microfluidic device to identify at least one B cell that produces antibodies capable of binding to cancer cells. The cancer cells can be the patient's own cancer cells. Also provided are methods of treating patients, methods of labeling or detecting cancer, engineered T or NK cells comprising antibodies or fragments thereof, and engineered antibody constructs.

Abstract: Systems and methods are provided for power beaming that increase power density at the target location by exploiting scattering from terrain. The disclosed systems and methods further provide a variable focus feature allowing the beam power to be concentrated at specified standoff distances from the transmitter and increase the radio frequency (RF) power handling of the receiver using an overvoltage protection circuit in the DC load.

Abstract: Provided herein are organic solvent-based processes for the removal of rubber from non-Hevea plants such as guayule shrubs. By the use of the processes, solid purified rubber can be obtained that contains 0.05-0.5 weight % dirt, 0.2-1.5 weight % ash, and 0.1-4 weight % resin (when it has been dried so as to contain 0.8 weight % volatile matter).

Abstract: The present invention relates to genetically modified B cells and their uses thereof, for example, for the treatment of a variety of diseases and disorders, including cancer, heart disease, inflammatory disease, muscle wasting disease, neurological disease, and the like. In certain embodiments, the invention relates to an isolated modified B cell (“CAR-B cell), capable of expressing a chimeric receptor (“CAR-B receptor”), wherein said chimeric receptor comprises (a) an extracellular domain; (b) a transmembrane domain; and (c) a cytoplasmic domain that comprises at least one signaling domain. In various embodiments, the invention comprises an isolated modified B cell, wherein said B cell is capable of expressing and secreting a payload, wherein the payload is not naturally expressed in a B cell or is expressed at higher levels than is naturally expressed in a B cell. In various embodiments, the payload is an antibody or fragment thereof.

Abstract: A system and method carried out on an Internet enabled user device for enhancing the in-store customer shopping experience that requires no registrations, logins, or mobile app for the customer and no new hardware, installation, or integration required for the retailer. A simple, cloud-based, customer-driven online marketing toolset for retailers that offer “one-click” solutions to meet the individual needs of their customers. In turn, increasing the lifetime value of each customer to build profitable customer relationships for the retailer. The invention comprises of a web page comprising a user-interactive, multimedia, HTML (hypertext markup language) web form with one or more modularized HTML user-interactive fields that can be enabled, disabled, or edited on the fly.

Abstract: A device to convert an existing pool skimmer assembly into a pressurizable pool skimmer assembly, thereby allowing the existing pool skimmer assembly to act with this existing pool pump in emergency situations, such as assisting firefighters with pool water for extinguishing local wildfires or house fires. A removable plug cap and o-rings enables the pool pump to draw the pool water from the pool main drain using the existing pool skimmer. This device can also be used to drain the pool for cleaning the pool or for winterizing the pool, without requiring an electrical sump pump.

Abstract: This application describes a device to convert an existing pool skimmer assembly into a pressurizable pool skimmer assembly, which allows the existing pool skimmer assembly to act with this existing pool pump in emergency situations, such as assisting firefighters with pool water for extinguishing local wildfires or house fires. This method utilizes a removable plug cap and o-rings to allow the pool pump to draw the pool water from the pool main drain using the existing pool skimmer. This device can also be used to drain the pool for cleaning the pool or for winterizing the pool, with out the need for an electrical sump pump.

Abstract: This application describes a device to convert an existing pool skimmer assembly into a pressurizable pool skimmer assembly which allows the existing pool skimmer assembly to act with this existing pool pump in emergency situations, such as assisting firefighters with pool water for extinguishing local wildfires or house fires. This method utilizes a removable plug cap and o-rings to allow the pool pump to draw the pool water from the poolmaid drain using the existing pool skimmer. This device can also be used to drain the pool for cleaning the pool or for winterizing the pool, with out the need for an electrical sump pump.

Abstract: An extra-labia urine voiding apparatus including a container sized and shaped to externally cover a vulval region of a female anatomy. The container has an open side and defines a reservoir that is adapted for receiving urine. The container also includes a substantially planar surface disposed at a top of the container adapted to face and generally surround a periphery of the vulval region. An extra-labia sealing structure is affixed to the planar surface of the top of the container. The sealing structure includes a pressure sensitive adhesive adapted to provide a generally fluid tight primary adhesive seal between the container and external tissue generally surrounding the vulval region. A blocking mechanism connected proximate the top of the container prevents escape of urine from the voiding apparatus and contact of urine with the vulval region of the female anatomy.

Abstract: An extra-labia urine voiding apparatus including a container sized and shaped to externally cover a vulval region of a female anatomy. The container has an open side and defines a reservoir that is adapted for receiving urine. The container also includes a surface disposed at a top of the container adapted to face and generally surround a periphery of the vulval region. The voiding apparatus also includes a conduit in fluid communication with the reservoir of the container and adapted for draining urine from the reservoir.

Abstract: This application describes a device to convert an existing pool skimmer assembly into a pressurizable pool skimmer assembly which allows the existing pool skimmer assembly to act with this existing pool pump in emergency situations, such as assisting firefighters with pool water for extinguishing local wildfires or house fires. This method utilizes a removable plug cap and o-rings to allow the pool pump to draw the pool water from the poolmaid drain using the existing pool skimmer. This device can also be used to drain the pool for cleaning the pool or for winterizing the pool, with out the need for an electrical sump pump.

Abstract: This invention describes a ring shaped adapter that is adapted to fit within a pool skimmer and have a pressure cap that will prevent debris from inadvertently being deposited within the pump system of the pool under construction. The ring shaped adapter and pressure cap will allow the pool to be drained using the pump system, without any additional equipment.

Abstract: An extra-labia urine voiding apparatus including a container sized and shaped to externally cover a vulval region of a female anatomy. The container has an open side and defines a reservoir that is adapted for receiving urine. The container also includes a surface disposed at a top of the container adapted to face and generally surround a periphery of the vulval region. The voiding apparatus also includes a conduit in fluid communication with the reservoir of the container and adapted for draining urine from the reservoir.

Abstract: This invention describes a ring shaped adapter that is adapted to fit within a pool skimmer and have a pressure cap that will prevent debris from inadvertently being deposited within the pump system of the pool under construction. The ring shaped adapter and pressure cap will allow the pool to be drained using the pump system, without any additional equipment.

Abstract: An extra-labia urine voiding apparatus including a container sized and shaped to externally cover a vulval region of a female anatomy. The container has an open side and defines a reservoir that is adapted for receiving urine. The container also includes a surface disposed at a top of the container adapted to face and generally surround a periphery of the vulval region. The voiding apparatus also includes a conduit in fluid communication with the reservoir of the container and adapted for draining urine from the reservoir.

Abstract: An extra-labia urine voiding apparatus including a container sized and shaped to externally cover a vulval region of a female anatomy. The container has an open side and defines a reservoir that is adapted for receiving urine. The container also includes a surface disposed at a top of the container adapted to face and generally surround a periphery of the vulval region. The voiding apparatus also includes a conduit in fluid communication with the reservoir of the container and adapted for draining urine from the reservoir.

Abstract: An extra-labia urine voiding apparatus including a container sized and shaped to externally cover a vulval region of a female anatomy. The container has an open side and defines a reservoir that is adapted for receiving urine. The container also includes a substantially planar surface disposed at a top of the container adapted to face and generally surround a periphery of the vulval region. An extra-labia sealing structure is affixed to the planar surface of the top of the container. The sealing structure includes a pressure sensitive adhesive adapted to provide a generally fluid tight primary adhesive seal between the container and external tissue generally surrounding the vulval region. A blocking mechanism connected proximate the top of the container prevents escape of urine from the voiding apparatus and contact of urine with the vulval region of the female anatomy.