Abstract: The invention described herein is a method of collecting genetic material by exposing a protein substrate to a source of genetic material for the purpose of obtaining, procuring, and storing genetic material such as RNA or DNA. The protein substrate is preferably comprised of collagen. The protein substrate is optionally capable of being solubilized or dissolved without disruption of the cell integrity, thus preserving the genetic material within a cell or the genetic material itself and allowing for subsequent analysis. Methods of solubilization of the protein substrate include enzymatic degradation or hydrolysis.