Abstract: Devices for treating vascular defects and associated systems and methods are disclosed herein. In some embodiments, for example, an occlusive device for treating an aneurysm includes a tubular structure having a first end portion with a first opening, a second end portion with a second opening, and a mesh surface extending between the first and second end portions. The occlusive device also includes a plurality of spiral struts coupled to the first end portion of the tubular structure and extending over the first opening. When the occlusive device is deployed within the aneurysm, the tubular structure and the plurality of spiral struts can be configured to self-expand such that the plurality of spiral struts span a neck of the aneurysm substantially within a single plane and the mesh surface of the tubular structure engages a wall of the aneurysm near the neck.

Abstract: A steam cracking unit including one or more electric resistance heating tubes electrically connected to a current source to generate heat via electrical resistance heating. Each resistance heating tube may include two or more tube sections. Each tube section may be independently supplied with a current. A controller may be configured to adjust the application of the current to one or more tube sections to control the electrical resistance heating of the one or more resistance heating tubes. In examples, the one or more electric heating tubes may be used as preheating tubes, cracking tubes, or both.

Abstract: A method and apparatus for high-purity hydrogen fired liquid hydrocarbon cracking. In one embodiment, the method may include preheating a liquid hydrocarbon feedstock in a first heat exchanger that is external to a furnace, adding steam to the preheated liquid hydrocarbon feedstock to create a fully or substantially fully vaporized stream, heating the fully or substantially fully vaporized stream in a second heat exchanger that is external to the furnace, and cracking the heated fully or substantially fully vaporized stream after it is preheated in the furnace to create a cracked gas stream comprising ethylene and hydrogen.

Abstract: Expandable devices for occluding bifurcation aneurysms are disclosed herein. Several of the embodiments are directed towards an expandable device comprising a mesh configured to be deployed at a treatment site including blood vessel bifurcation of a human patient so that the mesh extends across a neck of an aneurysm and prevents or limits blood flow through the mesh and into the aneurysm. The mesh can comprise one or more circumferentially discontinuous portions so that, when the device is deployed at the treatment site, the device does not substantially impede flow from a parent blood vessel to two or more branching blood vessels. Systems and methods for delivering an expandable device of the present technology are also disclosed herein.

Abstract: A masking tool system includes a first masking body and a second masking body. The first masking body includes a bore passing through a portion of the first masking body and a first sealing element disposed on a first end of the first masking body. The second masking body includes a bore passing through the second masking body and a second sealing element disposed on a first end of the second masking body. The system may also include a rod configured to pass through the bores of the first and second masking bodies and to secure the first and second masking bodies to a metallic article placed therebetween. A diagonal length of the masking tool system induces a wobbling rotation during processing.

Abstract: A piezoelectric device includes a piezoresonator body and a set of electrodes disposed on the piezoresonator body. The piezoresonator body includes a bulk region and a contact element integral with and protruding from the bulk region, and further includes opposing first and second surfaces. A pair of excitation electrodes are disposed on the first surface. A common electrode is disposed on the second surface. The piezoresonator body is characterized by a longitudinal axis and a transverse axis, and further characterized by a natural resonant frequency (v1) of first-order longitudinal standing vibrations along the transverse axis and a natural resonant frequency (v2) of second-order bending standing vibrations along the longitudinal axis, with v1<v2?1.1v1.

Abstract: Introduced here is a network-accessible platform (or simply “platform”) that is designed to monitor digital activities that are performed across different services to ascertain, in real time, threats to the security of an enterprise. In order to surface insights into the threats posed to an enterprise, the platform can apply machine learning models to data that is representative of digital activities performed on different services with respective accounts. Each model may be trained to understand what constitutes normal behavior for a corresponding employee with respect to a single service or multiple services. Not only can these models be autonomously trained for the employees of the enterprise, but they can also be autonomously applied to detect, characterize, and catalog those digital activities that are indicative of a threat.

Abstract: Introduced here is a network-accessible platform (or simply “platform”) that is designed to monitor digital activities that are performed across different services to ascertain, in real time, threats to the security of an enterprise. In order to surface insights into the threats posed to an enterprise, the platform can apply machine learning models to data that is representative of digital activities performed on different services with respective accounts. Each model may be trained to understand what constitutes normal behavior for a corresponding employee with respect to a single service or multiple services. Not only can these models be autonomously trained for the employees of the enterprise, but they can also be autonomously applied to detect, characterize, and catalog those digital activities that are indicative of a threat.

Abstract: Introduced here is a network-accessible platform (or simply “platform”) that is designed to monitor digital activities that are performed across different services to ascertain, in real time, threats to the security of an enterprise. In order to surface insights into the threats posed to an enterprise, the platform can apply machine learning models to data that is representative of digital activities performed on different services with respective accounts. Each model may be trained to understand what constitutes normal behavior for a corresponding employee with respect to a single service or multiple services. Not only can these models be autonomously trained for the employees of the enterprise, but they can also be autonomously applied to detect, characterize, and catalog those digital activities that are indicative of a threat.

Abstract: Introduced here is a network-accessible platform (or simply “platform”) that is designed to monitor digital activities that are performed across different services to ascertain, in real time, threats to the security of an enterprise. In order to surface insights into the threats posed to an enterprise, the platform can apply machine learning models to data that is representative of digital activities performed on different services with respective accounts. Each model may be trained to understand what constitutes normal behavior for a corresponding employee with respect to a single service or multiple services. Not only can these models be autonomously trained for the employees of the enterprise, but they can also be autonomously applied to detect, characterize, and catalog those digital activities that are indicative of a threat.

Abstract: A needle-free injector system includes a needle-free injector configured to deploy a dose of a treatment to a patient as an injection event, a gyroscope configured to monitor an orientation of the needle-free injector during the injection event, and a processor configured to perform steps of detecting that an actuator of the needle-free injector has deployed the dose in the injection event, monitoring a signal from the gyroscope during the injection event, determining an orientation of the needle-free injector during the injection event based on the signal from the gyroscope, determining whether the injection event was a treatment event including a successful delivery of the dose to the patient based on the orientation of the needle-free injector during the injection event, and transmitting information regarding the injection event to a server.

Abstract: An injector system includes an injector configured to deploy a dose of a treatment to a patient as an injection event, a gyroscope configured to monitor an orientation of the injector during the injection event, and a processor configured to perform steps of detecting that an actuator of the injector has deployed the dose in the injection event, monitoring a signal from the gyroscope during the injection event, determining an orientation of the injector during the injection event based on the signal from the gyroscope, determining whether the injection event was a treatment event including a successful delivery of the dose to the patient based on the orientation of the injector during the injection event, and transmitting information regarding the injection event to a server.

Abstract: A weed spot-spraying system is described for carrying out a spot-based weed spraying method based upon a classification value rendered from a sub-field image in accordance with a machine learning-based trained model applied by a processor to the sub-field image. The system includes a camera; a spray nozzle assembly including a spray nozzle; and a processor. The method carried out by the system includes acquiring, by the camera, a full field of view image of a crop floor. The method further includes extracting, from the full field of view image, a sub-field image corresponding to the spray nozzle positioned to provide a spray field extending over a part of the crop floor depicted in the sub-field image; rendering, by the processor in accordance with the machine learning-based trained model, a classification for the sub-field image; and selectively activating the spray nozzle in accordance with the classification for the sub-field image.

Abstract: The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain aldehyde dehydrogenase inhibitor compounds (also referred to herein as “ALDHI compounds”), that, inter alia, inhibit aldehyde dehydrogenase enzyme ALDH1A3. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit ALDH1A3 enzyme; to treat disorder (e.g., diseases) that are ameliorated by the inhibition of ALDHIA3 enzyme; to treat a proliferative disorder, cancer, obesity, diabetes, a cardiovascular disorder, etc.

Abstract: A needle-free injector system includes a needle-free injector configured to deploy a dose of a treatment to a patient as an injection event, a gyroscope configured to monitor an orientation of the needle-free injector during the injection event, and a processor configured to perform steps of detecting that an actuator of the needle-free injector has deployed the dose in the injection event, monitoring a signal from the gyroscope during the injection event, determining an orientation of the needle-free injector during the injection event based on the signal from the gyroscope, determining whether the injection event was a treatment event including a successful delivery of the dose to the patient based on the orientation of the needle-free injector during the injection event, and transmitting information regarding the injection event to a server.

Abstract: Low carbon dioxide-emitting processes and systems for steam cracking hydrocarbons to produce products such as ethylene are described. The processes and systems involve cracking the feed in a furnace that is configured to burn a hydrogen-rich fuel, which produces less carbon dioxide than methane, which is typically used as fuel for such furnaces. The hydrogen-rich stream can be isolated and recycled from the cracker tail gas.

Abstract: A system, method, and computer-readable medium are disclosed for browser based polling of jobs used to build a web page of a web application. A web browser builds the web page of the web application and connects with one or more web services for jobs used to build the web page of the web application. A reusable service from a library is downloaded and is used at the web browser to poll the jobs as they are received from the web services. Polling the jobs is performed until download is complete. The web page application is updated when the download is complete.

Abstract: Methods for restoring blood flow in occluded blood vessels using an apparatus having a self-expandable distal segment that is pre-formed to assume a superimposed structure in an unconstrained condition but can be made to take on a volume-reduced form making it possible to introduce it with a microcatheter and a push wire arranged at the proximal end, with the distal segment in its superimposed structure assuming the form of a longitudinally open tube and having a mesh structure of interconnected strings or filaments or struts. In a preferred embodiment, the distal segment has a tapering structure at its proximal end where the strings or filaments or struts converge at a connection point.

Abstract: Devices, systems, and methods for delivering an expandable member to a treatment site within a blood vessel are disclosed herein. According to some embodiments, a delivery system includes a core member and a coupling assembly carried by the core member. The coupling assembly may include an engagement member configured to engage an inner surface of an expandable member extending over the coupling assembly to facilitate delivery of the expandable member from an elongated shaft and/or resheathing of the expandable member into the elongated shaft. The engagement member can be movable between a radially compressed configuration and a radially expanded configuration.

Abstract: Expandable devices for occluding bifurcation aneurysms are disclosed herein. Several of the embodiments are directed towards an expandable device comprising a mesh configured to be deployed at a treatment site including blood vessel bifurcation of a human patient so that the mesh extends across a neck of an aneurysm and prevents or limits blood flow through the mesh and into the aneurysm. The mesh can comprise one or more circumferentially discontinuous portions so that, when the device is deployed at the treatment site, the device does not substantially impede flow from a parent blood vessel to two or more branching blood vessels. Systems and methods for delivering an expandable device of the present technology are also disclosed herein.