Patents by Inventor Mark Philip DODSWORTH

Mark Philip DODSWORTH has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Aldehyde Dehydrogenase Inhibitors and Their Therapeutic Use
    Publication number: 20240174634
    Abstract: The present invention pertains generally to the field of therapeutic compounds. More specifically the present invention pertains to certain aldehyde dehydrogenase inhibitor compounds (also referred to herein as “ALDHI compounds”), that, inter alia, inhibit aldehyde dehydrogenase enzyme ALDH1A3. The present invention also pertains to pharmaceutical compositions comprising such compounds, and the use of such compounds and compositions, both in vitro and in vivo, to inhibit ALDH1A3 enzyme; to treat disorder (e.g., diseases) that are ameliorated by the inhibition of ALDHIA3 enzyme; to treat a proliferative disorder, cancer, obesity, diabetes, a cardiovascular disorder, etc.
    Type: Application
    Filed: December 10, 2021
    Publication date: May 30, 2024
    Applicant: Cancer Research Technology Limited
    Inventors: Christopher Stephen KERSHAW, Mohammed ALJARAH, Dan NICULESCU-DUVAZ, Mark Philip DODSWORTH, Cinzia BORDONI, Caroline SPRINGER
  • 6,7-DIHYDRO-5H-PYRIDO[2,3-C]PYRIDAZINE DERIVATIVES AND RELATED COMPOUNDS AS BCL-XL PROTEIN INHIBITORS AND PRO-APOPTOTIC AGENTS FOR TREATING CANCER
    Publication number: 20220363677
    Abstract: Compounds of formula (I): wherein Het, Het1, Het2, A4, A5, Z1, R1, R2 and R3 are as defined in the description. Medicaments.
    Type: Application
    Filed: July 28, 2020
    Publication date: November 17, 2022
    Inventors: Tibor NOVÁK, James Edward Paul DAVIDSON, Attila PACZAL, Jérôme-Benoît STARCK, András KOTSCHY, James Brooke MURRAY, Simon BEDFORD, Maïa CHANRION, Frédéric COLLAND, Mark Philip DODSWORTH, Andràs HERNER, Ana Leticia MARAGNO, Emma SANDERS, Mátyás Pál TIMÁRI, Paul WEBB
  • 3,6-DIAMINO-PYRIDAZIN-3-YL DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND THEIR USES AS PRO-APOPTOTIC AGENTS
    Publication number: 20220289734
    Abstract: Compounds of formula (I): wherein Het1, Het2, R1, R2 and R3 are as defined in the description.
    Type: Application
    Filed: July 28, 2020
    Publication date: September 15, 2022
    Inventors: James Edward Paul DAVIDSON, Tibor NOVÁK, Attila PACZAL, András KOTSCHY, Jérôme-Benoît STARCK, James Brooke MURRAY, Simon BEDFORD, Maïa CHANRION, Frédéric COLLAND, Patrice DESOS, Mark Philip DODSWORTH, Petra DUNKEL, Andràs HERNER, Zoltán MADARÁSZ, Ana Leticia MARAGNO, Márk MOLNÁR, Miklós NYERGES, Rachel Jane PARSONS, Monika RUDASOVÁ, Ágnes STROFEK, Marianna SZIGETI, Mátyás Pál TIMÁRI, Paul WEBB