Abstract: A method of operating a computer system to convert non-interactive digital documents, such as electronic text and image files into interactive digital worksheets is provided. The method includes operating the computer system to prompt a user, such as a teacher for example, to identify a Base Document file accessible to the computer system. The computer system processes the Base Document to produce a corresponding dynamic document which allows the user to overlay data input fields overlaid. The user's overlays are recorded in a database along with meta-data that has been input by the user and which is associated with the overlaid data input fields. The meta-data that is recorded includes instructions determining the manner in which a further computational device, for example a student's PC, smartphone or tablet, interactively presents information of the base document to an end user, such as a student.

Abstract: A drive assembly for a drug delivery device comprises a rotation member being configured to be rotated in a first direction during setting of a dose of a drug and to be rotated in a second direction during delivery of the dose, a drive component being configured to follow rotational movement of the rotation member in the second direction during delivery of the dose and a stop member being configured to prevent rotational movement of the drive component in the first direction. The drive component comprises a first drive part and a second drive part, coupled to each other such that relative rotational movement of the first and second drive parts is prevented and relative axial movement is permitted.

Abstract: An assembly for a drug delivery device is provided, comprising a housing, a rotation member adapted and arranged to be rotated in a first and in a second rotational direction with respect to the housing in an operational mode of the assembly, a drive member which is configured to mechanically cooperate with the rotation member such that the drive member follows rotation of the rotation member when the rotation member is rotated in the second rotational direction and such that the rotation member rotates with respect to the drive member when the rotation member is rotated in the first rotational direction, and a piston rod. The assembly further comprises at least one biasing member which is adapted and arranged to provide a force tending to bring the rotation member and the drive member out of mechanical cooperation in the operational mode. The assembly is switchable from the operational mode into a reset mode.

Abstract: A drive assembly for a medication delivery device is provided which is switchable from an operational state to a resetting state and which comprises: a housing having a proximal end and a distal end, a drive member adapted to be rotated with respect to the housing, and a stop member adapted to prevent rotational movement of the drive member in a first direction with respect to the housing and to permit rotational movement of the drive member in a second direction with respect to the housing, the second direction being opposite to the first direction. In the operational state of the drive assembly the stop member is held in engagement with the drive member, and for switching into the resetting state of the drive assembly the stop member is enabled to disengage from the drive member caused by gravity due to the weight of the stop member.

Abstract: The drive mechanism comprises a drive member inside a housing, a rotation member and a dose member. The drive member is rotatable with respect to the housing. The rotation member is also rotatable and unidirectionally rotationally engaged with the drive member. The dose member is able to move along a set/deliver path between a first axial position and a second axial position in either direction or to move along a cancel path from the second axial position to the first axial position. An engagement of the dose member with the rotation member causes the rotation member to rotate when the dose member is moved along the set/deliver path. The drive member is not rotated when the dose member is moved along the cancel path. A button in/out spline can be provided for the set/deliver path and a cancel spline for the cancel path.

Abstract: A drive mechanism for a drug delivery device which can be switched between a normal operation state and a reset state comprises of a housing having a proximal end and a distal end, a rotation member which is adapted to rotate in a first direction and in a second direction with respect to the housing, a drive member, wherein in the normal operation state the rotation member is coupled with the drive member so that the drive member follows rotational movement of the rotation member in the second direction, a piston rod, wherein in the normal operation state the piston rod is displaced in a distal direction with respect to the housing when the drive member rotates in the second direction with respect to the housing, a stop member, wherein in the normal operation state the stop member is coupled with the drive member so that the stop member prevents rotational movement of the drive member with respect to the housing in the first direction, and a separation member for switching the operation state, the separation

Abstract: A drug delivery device is proposed, which comprises a housing, a drive member which is movably retained within the housing, a piston rod which is operatively coupled to the drive member, wherein the drug delivery device is configured to convert movement of the drive member with respect to the housing into movement of the piston rod with respect to the drive member, wherein a surface of the drive member is provided with one or a plurality of indication elements, and wherein the drug delivery device is adapted to display at least one of the indication elements through the housing. Furthermore it is proposed to use a single member in a drug delivery device for driving movement of a piston rod of the device and for displaying dose related information to a user of the device.

Abstract: A drive member and a rotation member are rotatable with respect to a housing. A stop member is rotationally locked with the housing. Clutches unidirectionally rotationally engage the drive member with the rotation member and with the stop member when a unit is attached to the housing. A separating member is disposed between the rotation member and the stop member. The separating member causes a separation of the rotation member, the drive member and the stop member when the unit is removed. A coupling feature of the separating member is provided to engage the unit and to move the separating member when the unit is being attached to the housing or is being removed.

Abstract: The embodiments described herein provide in one aspect, a method of providing security when accessing a user account of a browser-based communications application, the method comprising: providing a communications server, the communications server configured to access personal information management (PIM) data for the user account, the PIM data comprising a plurality of non-security data items; receiving, at the communications server, a connection request from a remote system, the connection request comprising at least one connection parameter of the remote system; determining if the at least one connection parameter of the remote system is acceptable based on at least one non-security data item of the plurality of non-security data items; allowing access to the user account based on said determining; and sending security awareness data for the user account from the communications server, the security awareness data comprising at least one second non-security data item of the plurality of non-security data it

Abstract: There is provided a GaN single crystal at least about 2.75 millimeters in diameter, with a dislocation density less than about 104 cm?1, and having substantially no tilt boundaries. A method of forming a GaN single crystal is also disclosed. The method includes providing a nucleation center, a GaN source material, and a GaN solvent in a chamber. The chamber is pressurized. First and second temperature distributions are generated in the chamber such that the solvent is supersaturated in the nucleation region of the chamber. The first and second temperature distributions have different temperature gradients within the chamber.

Abstract: A sub-circuit for facilitating the synchronization of event-based samples of signals in a cross-correlation circuit utilizing event-based sampling is provided. The sub-circuit alternatively integrates one of the signals to be cross-correlated and alternates between the signals in response to the output of a hysteretic comparator. The invention extends to a method of manipulating the input signals to a cross-correlation circuit utilizing event-based sampling so-as to facilitate the synchronization of the event-based samples of the signals.

Abstract: A system and methods are described for generating reagent ions and product ions for use in a mass spectrometry system. Applications for the system and method are also disclosed for detecting volatile organic compounds in trace concentrations. A microwave or high-frequency RF energy source ionizes particles of a reagent vapor to form reagent ions. The reagent ions enter a chamber, such as a drift chamber, to interact with a fluid sample. An electric field directs the reagent ions and facilitates an interaction with the fluid sample to form product ions. The reagent ions and product ions then exit the chamber under the influence of an electric field for detection by a mass spectrometer module. The system includes various control modules for setting values of system parameters and analysis modules for detection of mass and peak intensity values for ion species during spectrometry and faults within the system.

Abstract: An intravascular implant delivery system carries an implant by retaining an engagement member engaging the implant in a position proximal of an aperture at a distal end of the delivery system. The engagement member is retained proximal to the aperture by a cord that obstructs the movement of the engagement member through the aperture. The engagement member is free to rotate and move within an area defined by the delivery system, allowing the implant to react to forces imparted to the implant by the movement of the delivery system and implant through a delivery catheter. Once the implant is in a desired implant position, the cord is moved away from an aperture and the engagement member is allowed to move away from the delivery system.

Abstract: A method for removing defects at high pressure and high temperature (HP/HT) or for relieving strain in a non-diamond crystal commences by providing a crystal, which contains defects, and a pressure medium. The crystal and the pressure medium are disposed in a high pressure cell and placed in a high pressure apparatus, for processing under reaction conditions of sufficiently high pressure and high temperature for a time adequate for one or more of removing defects or relieving strain in the single crystal.

Abstract: A method of manufacturing one or more graphene devices is disclosed. A thin film growth substrate is formed directly on a device substrate. Graphene is formed on the thin film growth substrate. A transistor is also disclosed, having a device substrate and a source supported by the device substrate. The transistor also has a drain separated from the source and supported by the device substrate. The transistor further has a single layer graphene (SLG) channel grown partially on and coupling the source and the drain. The transistor also has a gate aligned with the SLG channel, and a gate insulator between the gate and the SLG channel. Integrated circuits and other apparati having a device substrate, a thin film growth substrate formed directly on at least a portion of the device substrate, and graphene formed directly on at least a portion of the thin film growth substrate are also disclosed.

Abstract: Methods and devices for positioning a group, array, series or arrangement of plumb poles in a specific relationship relative to each other, whereby a first pole is inserted in a horizontal clamshell attached to a moveable platform, retained and raised to a vertical position and plumbed. The moveable platform is positioned over the pole insertion location and the pole is released. The process is repeated at as many holes as needed. Other embodiments are used to set the poles at specific heights, or angles.

Abstract: A device is used to precisely deliver the treatment plan created by an automatic planning system by positioning a single low energy radiation source, or a plurality of low energy sources connected to each other, in a predetermined parallel, planar, or similar geometry, each source equipped with blocking and attenuation mechanisms, thereby delivering a plurality of parallel overlapping beams indexed on a millimeter or submillimeter grid such that a concentration of dose is achieved at a variable depth in tissue relative to the dose where the radiation first enters the tissue. A plurality of overlapping beams indexed on a millimeter or submillimeter grid can converge on a target volume loaded with gold nanoparticles to deliver a tumorcidal dose of radiation in as little as a single session to tumor cells but not to normal cells or to deliver serial radiosurgical treatments.

Abstract: An intravascular implant delivery system carries an implant by retaining an engagement member engaging the implant in a position proximal of an aperture at a distal end of the delivery system. The engagement member is retained proximal to the aperture by a cord that obstructs the movement of the engagement member through the aperture. The engagement member is free to rotate and move within an area defined by the delivery system, allowing the implant to react to forces imparted to the implant by the movement of the delivery system and implant through a delivery catheter. Once the implant is in a desired implant position, the cord is moved away from an aperture and the engagement member is allowed to move away from the delivery system.

Abstract: A method for growing a crystalline composition, the first crystalline composition may include gallium and nitrogen. The crystalline composition may have an infrared absorption peak at about 3175 cm?1, with an absorbance per unit thickness of greater than about 0.01 cm?1. In one embodiment, the composition ay have an amount of oxygen present in a concentration of less than about 3×1018 per cubic centimeter, and may be free of two-dimensional planar boundary defects in a determined volume of the first crystalline composition.

Abstract: A system and methods are described for generating reagent ions and product ions for use in a mass spectrometry system. Applications for the system and method are also disclosed for detecting volatile organic compounds in trace concentrations. A microwave or high-frequency RF energy source ionizes particles of a reagent vapor to form reagent ions. The reagent ions enter a chamber, such as a drift chamber, to interact with a fluid sample. An electric field directs the reagent ions and facilitates an interaction with the fluid sample to form product ions. The reagent ions and product ions then exit the chamber under the influence of an electric field for detection by a mass spectrometer module. The system includes various control modules for setting values of system parameters and analysis modules for detection of mass and peak intensity values for ion species during spectrometry and faults within the system.