Patents by Inventor Mark Pichowicz

Mark Pichowicz has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • MODULATORS OF G PROTEIN-COUPLED RECEPTOR 88
    Publication number: 20240132450
    Abstract: Disclosed are compounds of the formula (I) and pharmaceutically acceptable salts thereof: (I) wherein Ring A, Ring B, Ring C, R1, R2, R3, R4, R5, L, m, n, and p are as defined herein. The compounds are modulators of G-protein coupled receptor 88 (GPR88). Also disclosed are pharmaceutical compositions comprising the compounds; and the compounds for use in the treatment of diseases mediated by GPR88, including Tourette's Syndrome, Huntington's Disease (HD), Addiction, Parkinson's Disease (PD), Schizophrenia, Alzheimer's disease, and Attention Deficit Hyperactivity Disorder (ADHD).
    Type: Application
    Filed: December 17, 2021
    Publication date: April 25, 2024
    Inventors: Martin Quibell, Tim Schulz-Utermoehl, Fraser Murray, Mark Pichowicz
  • ENZYME INHIBITORS
    Publication number: 20240059691
    Abstract: The present invention provides compounds of formula (I): compositions comprising such compounds; the use of such compounds in medicine; and methods of treating patients with such compounds; wherein A, W, R5, n, Z, X, Y and B are as defined herein. The present invention also relates to compounds useful as synthetic intermediates of compounds of formula (I).
    Type: Application
    Filed: December 1, 2021
    Publication date: February 22, 2024
    Inventors: Mitchell Lewis CHILDS, Rebecca Louise DAVIE, Hannah Joy EDWARDS, David Michael EVANS, William Jack GREVES, Simon Teanby HODGSON, Alessandro MAZZACANI, Carl Leslie NORTH, Alicja Stela OBARA, Michael Bryan ROE, David Philip ROOKER, Michael John STOCKS, Louise Michelle BIRCH, Mark PICHOWICZ, Rachael PITTAWAY, Alun John SMITH, Adam Eric THROUP, Joseph William WRIGGLESWORTH, Xuezheng YANG, David Edward CLARK
  • PYRIDINE AND PYRIMIDINE BASED COMPOUNDS AS WNT SIGNALING PATHWAY INHIBITORS FOR THE TREATMENT OF CANCER
    Publication number: 20140350015
    Abstract: The present invention relates to pyridine and pyrimidine based compounds, pharmaceutical compositions comprising these compounds and their potential use as therapeutic agents for the treatment and/or prevention of cancer.
    Type: Application
    Filed: June 12, 2014
    Publication date: November 27, 2014
    Inventors: Edward McDonald, Julian Blagg, Mark Pichowicz, Simon Ross Crumpler
  • Pyridine and pyrimidine based compounds as Wnt signaling pathway inhibitors for the treatment of cancer
    Patent number: 8778925
    Abstract: The present invention relates to pyridine and pyrimidine based compounds, pharmaceutical compositions comprising these compounds and their potential use as therapeutic agents for the treatment and/or prevention of cancer.
    Type: Grant
    Filed: October 6, 2009
    Date of Patent: July 15, 2014
    Assignee: Cancer Research Technology Ltd.
    Inventors: Edward McDonald, Julian Blagg, Mark Pichowicz, Simon Ross Crumpler
  • PYRIDINE AND PYRIMIDINE BASED COMPOUNDS AS WNT SIGNALING PATHWAY INHIBITORS FOR THE TREATMENT OF CANCER
    Publication number: 20110190297
    Abstract: The present invention relates to pyridine and pyrimidine based compounds, pharmaceutical compositions comprising these compounds and their potential use as therapeutic agents for the treatment and/or prevention of cancer.
    Type: Application
    Filed: October 6, 2009
    Publication date: August 4, 2011
    Inventors: Edward McDonald, Julian Blagg, Mark Pichowicz, Simon Ross Crumpler