Abstract: The present invention relates to a spray dried plasma composition having one or more of the following characteristics: when reconstituted, largely amorphous and has no cholesterol crystals; when reconstituted, the number of large particulates is reduced; has low residual moisture; reconstitutes rapidly in under four minutes; highly stable when stored under refrigeration, at room temperature or at elevated temperatures and allows for storage for longer periods of time; when reconstituted, exhibits recovery of the most fragile of proteins, including von Willebrand's factor; when reconstituted with Sterile Water for Injection (SWFI), reconstituted plasma is at a pH that is near normal plasma pH, and does so without treatment or storage in CO2 or other pH adjustment; and when reconstituted, has reduced complement activation (C5A, C3A).

Abstract: The present invention relates to a spray dried plasma composition having one or more of the following characteristics: when reconstituted, largely amorphous and has no cholesterol crystals; when reconstituted, the mean size of large particulates is reduced; has low residual moisture; reconstitutes rapidly in under four minutes; highly stable when stored under refrigeration, at room temperature or at elevated temperatures and allows for storage for longer periods of time; when reconstituted, exhibits recovery of the most fragile of proteins, including von Willebrand's factor; when reconstituted with Sterile Water for Injection (SWFI), reconstituted plasma is at a pH that is near normal plasma pH, and does so without treatment or storage in CO2 or other pH adjustment.

Abstract: The spray dried plasma by the nature of its characteristics and the process by which it is made allows for a dried plasma with reduced pathogens. It has at least three aspects of pathogen reduction that results in a plasma product with reduced or no pathogens. The first aspect relates to a spray drying disposable and machine that eliminates or minimizes the introduction of pathogens into the spray drying process and is referred to as the anti-contamination process. The second aspect of pathogen reduction relates to the spray drying process and parameters that reduces pathogens that may be present in the donor plasma, and/or inhibit pathogen growth and/or pathogen proliferation introduced by the donor plasma. The third aspect results in reduced pathogens occurring during storage of the dried plasma wherein the manufacturing and storage conditions are such that pathogens are reduced, and/or pathogen growth and/or pathogen proliferation are inhibited.

Abstract: A video sample rate converter for converting decoded SMPTE D2 interleaved component video to SMPTE D1 interleaved component video includes a single modified multi-tap finite impulse response ("FIR") digital filter which alternately functions as a data selector and two-point linear interpolator, and as a four-point polyphase interpolator. The FIR filter uses time variant switched filter coefficients and a selectively inhibited output clock signal.

Abstract: A method and apparatus for keying digital color TV signals to avoid "stairstepping" of pixels at the edges of the key while retaining a hard switch between the keyed scenes. This is achieved by comparing successive digital keying signals with a desired digital clip level. In the event that the clip level occurs between two successive digital signals an interpolation of the clip level between these is created fractionally. A digital representation of this fraction is then included in the keying signal so that keying is accomplished on a sub-pixel basis without acutally increasing the frequency of sampling.

Abstract: A method and apparatus for keying digital color TV signals without exceeding the normal sampling frequency (13.5 MHz) and without obtaining a degraded image. A digital keying signal and a digital color TV signal are supplied to upsamplers (10,12), respectively, which double the sampling frequency of the incoming signal by linear interpolation. The 27 MHz sampled outputs are keyed in multiplier (14). In one line to a switch (24) the 27 MHz, 12 MHz bandwidth keyed signal is passed through low pass filter (16) and demultiplexer (18). The latter removes each alternate sample to provide a 13.5 MHz signal of 6 MHz bandwidth. In a second line to the switch the keyed signal is demultiplexed to provide a signal which would have resulted without upsampling, which is then delayed (22). Edge detector (26) senses high frequency keying signals and controls switch (24). In the absence of such high frequency keying signals the signal to the second line to the switch is taken.

Abstract: A method and apparatus for keying TV signals. A keying signal, K, is employed to create first and second modified keying signals, K(A) and K(B), which commence at independent points in time. The modified signals are compared and, as a result, a revised keying signal, R, is produced commencing at the leading edge of one modified keying signal and terminating at the trailing edge of the other. The operator selects R according to one of the two rules (i), (ii), the selection being by trial and error:rule (i):if K(A)>K(B) then R=K(A)if K(A)<K(B) then R=K(B)rule (ii) (which is the converse of rule (i)):if K(A)>K(B) then R=K(B)if K(A)<K(B) then R=K(A).In this manner, the revised keying signal R can be made to coincide with the video signal, V, to be keyed.