Patents by Inventor Mark R. Ehrhardt

Mark R. Ehrhardt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • High-resolution NMR spectroscopy of molecules encapsulated in low-viscosity fluids
    Patent number: 6486672
    Abstract: The present invention provides a method for reducing the correlation time for global tumbling for analysis of proteins and other macromolecules by NMR spectroscopy. The method comprises placing a macromolecule, hydrated and without significant structure perturbation, within a reverse micelle in a suitable fluid medium of low viscosity. A high pressure NMR cell for use with the method of the present invention is also disclosed.
    Type: Grant
    Filed: January 25, 2001
    Date of Patent: November 26, 2002
    Inventors: A. Joshua Wand, Mark R. Ehrhardt, Peter F. Flynn
  • Apparatus and method for high pressure NMR spectroscopy
    Patent number: 6362624
    Abstract: The present invention provides a pressure cell for pressurizing materials for use in NMR spectroscopy, comprising a sample tube made of sapphire for placing the material, the tube being closed at one end, a housing for holding the sample tube such that the material in the tube can be pressurized, a cove for closing the housing, the cover having an inlet for pressuring the material, means for sealing the cover to the housing, and means of sealing the housing to the sample tube.
    Type: Grant
    Filed: October 27, 1999
    Date of Patent: March 26, 2002
    Assignee: The Research Foundation of State University of New York
    Inventors: Andrew J. Wand, Mark R. Ehrhardt, Jeffrey L. Urbauer
  • NMR spectroscopy of large proteins
    Patent number: 6198281
    Abstract: The present invention provides a method for reducing the correlation time for global tumbling for analysis of proteins and other macromolecules by NMR spectroscopy. The method comprises placing a macromolecule, hydrated and without significant structure perturbation, within a reverse micelle in a suitable fluid medium of low viscosity. A high pressure NMR cell for use with the method of the present invention is also disclosed.
    Type: Grant
    Filed: May 7, 1999
    Date of Patent: March 6, 2001
    Assignee: The Research Foundation of State University of New York
    Inventors: A. Joshua Wand, Mark R. Ehrhardt, Peter F. Flynn
  • Apparatus and method for high pressure NMR spectroscopy
    Patent number: 5977772
    Abstract: A Pressure Cell for pressurizing material for use in NMR spectroscopy, comprising a sample tube made of sapphire for placing the material; the tube being closed at one end, a housing for holding the sample tube such that the material in the tube can be pressurized, a cover for closing the housing, the cover having an inlet for pressuring the material, means of sealing the cover to the housing; and means of sealing the housing to the sample tube.
    Type: Grant
    Filed: November 12, 1997
    Date of Patent: November 2, 1999
    Assignee: Research Foundation of State University of New York, The
    Inventors: Andrew J. Wand, Mark R. Ehrhardt, Jeffrey L. Urbauer