Patents by Inventor Mark R. Hurle

Mark R. Hurle has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7049422
    Abstract: TR7 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing TR7 polypeptides and polynucleotides in the design of protocols for the treatment of chronic and acute inflammation, arthritis, septicemia, autoimmune diseases (such as inflammatory bowel disease and psoriasis), transplant rejection, graft versus host disease, infection, stroke, ischemia, acute respiratory disease syndrome, restenosis, brain injury, AIDS, bone diseases, cancer (such as lymphoproliferative disorders), atherosclerosis, and Alzheimers disease, among others and diagnostic assays for such conditions.
    Type: Grant
    Filed: September 15, 2003
    Date of Patent: May 23, 2006
    Assignee: SmithKline Beecham Corporation
    Inventors: Keith Charles Deen, Mark R. Hurle, Peter Young, Kong B. Tan
  • Publication number: 20040132057
    Abstract: TR7 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing TR7 polypeptides and polynucleotides in the design of protocols for the treatment of chronic and acute inflammation, arthritis, septicemia, autoimmune diseases (such as inflammatory bowel disease and psoriasis), transplant rejection, graft versus host disease, infection, stroke, ischemia, acute respiratory disease syndrome, restenosis, brain injury, AIDS, bone diseases, cancer (such as lymphoproliferative disorders), atherosclerosis, and Alzheimers disease, among others and diagnostic assays for such conditions.
    Type: Application
    Filed: September 15, 2003
    Publication date: July 8, 2004
    Inventors: Keith Charles Deen, Mark R. Hurle, Peter Young, K. B. Tan
  • Patent number: 6660839
    Abstract: TR7 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing TR7 polypeptides and polynucleotides in the design of protocols for the treatment of chronic and acute inflammation, arthritis, septicemia, autoimmune diseases (such as inflammatory bowel disease and psoriasis), transplant rejection, graft versus host disease, infection, stroke, ischemia, acute respiratory disease syndrome, restenosis, brain injury, AIDS, bone diseases, cancer (such as lymphoproliferative disorders), atherosclerosis, and Alzheimers disease, among others and diagnostic assays for such conditions.
    Type: Grant
    Filed: May 19, 1999
    Date of Patent: December 9, 2003
    Assignee: SmithKline Beecham Corporation
    Inventors: Keith Charles Deen, Mark R. Hurle, Peter Young, Kong B. Tan
  • Publication number: 20020004223
    Abstract: FHAR1 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing FHAR1 polypeptides and polynucleotides in diagnostic assays.
    Type: Application
    Filed: February 9, 2001
    Publication date: January 10, 2002
    Inventors: Bin-Bing Zhou, Yuan Zhu, Priya Chaturvedi, Mark R. Hurle, Xiaotong Li
  • Patent number: 6013476
    Abstract: TR7 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing TR7 polypeptides and polynucleotides in the design of protocols for the treatment of chronic and acute inflammation, arthritis, septicemia, autoimmune diseases (such as inflammatory bowel disease and psoriasis), transplant rejection, graft versus host disease, infection, stroke, ischemia, acute respiratory disease syndrome, restenosis, brain injury, AIDS, bone diseases, cancer (such as lymphoproliferative disorders), atherosclerosis, and Alzheimers disease, among others and diagnostic assays for such conditions.
    Type: Grant
    Filed: October 28, 1997
    Date of Patent: January 11, 2000
    Assignee: SmithKline Beecham Corporation
    Inventors: Keith Charles Deen, Mark R. Hurle, Peter Young, K. B. Tan
  • Patent number: 5932446
    Abstract: HMVAB41 polypeptides and polynucleotides and methods for producing such polypeptides by recombinant techniques are disclosed. Also disclosed are methods for utilizing HMVAB41 polypeptides and polynucleotides in the design of protocols for the treatment of cancer, inflammation, autoimmunity, allergy, asthma, rheumatoid arthritis, CNS inflammation, cerebellar degeneration, Alzheimer's disease, Parkison's disease, multiple sclerosis, amylotrophic lateral sclerosis, head injury damage, and other neurological abnormalities, septic shock, sepsis, stroke, osteoporosis, osteoarthritis, ischemia reperfusion injury, cardiovascular disease, kidney disease, liver disease, ischemic injury, myocardial infarction, hypotension, hypertension, AIDS, myelodysplastic syndromes and other hematologic abnormalities, aplastic anemia, male pattern bladness, and bacterial, fungal, protozoan and viral infections, among others, and diagnostic assays for such conditions.
    Type: Grant
    Filed: November 26, 1997
    Date of Patent: August 3, 1999
    Assignee: SmithKline Beecham Corporation
    Inventors: Kathleen Theresa Gallagher, Mark R Hurle, Kristine Kay Kikly