Patents by Inventor Mark R. Kennedy
Mark R. Kennedy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240070951Abstract: A system for producing conversation-driven character animation includes a computing platform having processing hardware and a system memory storing software code, the software code including multiple trained machine learning (ML) models. The processing hardware executes the software code to obtain a conversation understanding feature set describing a present state of a conversation between a digital character and a system user, and to generate an inference, using at least a first trained ML model of the multiple trained ML models and the conversation understanding feature set, the inference including labels describing a predicted next state of a scene within the conversation. The processing hardware further executes the software code to produce, using at least a second trained ML model of the multiple trained ML models and the labels, an animation stream of the digital character participating in the predicted next state of the scene within the conversation.Type: ApplicationFiled: August 24, 2022Publication date: February 29, 2024Inventors: Sanchita Tiwari, Justin Ali Kennedy, Mark R. Brashear, Daniel Cahall, Dumene Comploi, Dirk Van Dall, Keith Comito
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Publication number: 20240013858Abstract: Methods for determining a variant frequency in a test sample from a subject, and methods for labeling sequencing reads as having or not having a variant are described herein. Exemplary methods include generating a reference match score and a variant match score by aligning sequencing reads to a corresponding variant sequence and a corresponding reference sequence, and labeling the sequencing read as having or not having the variant based on the determined match scores. Also described herein are methods monitoring disease progression and methods of treating a subject having a disease. Further described are devices and systems for implementing such methods.Type: ApplicationFiled: September 23, 2021Publication date: January 11, 2024Applicant: Foundation Medicine, Inc.Inventors: Jonathan F. FREIDIN, Mark R. KENNEDY, Alyssa ANTONOPOULOS
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Patent number: 8685347Abstract: A cap having a core structure dimensioned to receive a pipette therethrough. The cap includes two axially aligned frangible seals that are affixed to the core structure in a spaced-apart relationship. The frangible seals include a foil layer and are constructed so that air passageways are formed between the frangible seals and a pipette tip when the pipette tip penetrates the frangible seals. The cap optionally includes a filter interposed between the first and second frangible seals.Type: GrantFiled: November 15, 2011Date of Patent: April 1, 2014Assignee: Gen-Probe IncorporatedInventors: Daniel L. Kacian, Mark R. Kennedy, Nick M. Carter
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Publication number: 20140053662Abstract: A cap having a core structure dimensioned to receive a pipette therethrough. The cap includes two axially aligned frangible seals that are affixed to the core structure in a spaced-apart relationship. The frangible seals include a foil layer and are constructed so that air passageways are formed between the frangible seals and a pipette tip when the pipette tip penetrates the frangible seals. The cap optionally includes a filter interposed between the first and second frangible seals.Type: ApplicationFiled: November 15, 2011Publication date: February 27, 2014Applicant: GEN-PROBE INCORPORATEDInventors: Daniel L. Kacian, Mark R. Kennedy, Nick M. Carter
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Patent number: 8535621Abstract: A cap having a plurality of rib structures situated on an inner wall of the cap to facilitate the formation of air passageways as the cap is penetrated by a pipette tip. The air passageways aid in venting air from a fluid-holding vessel closed with the cap.Type: GrantFiled: June 17, 2008Date of Patent: September 17, 2013Assignee: Gen-Probe IncorporatedInventors: Mordi I. Iheme, Daniel L. Kacian, Mark R. Kennedy
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Publication number: 20130160574Abstract: A cap having a core structure dimensioned to receive a pipette therethrough. The cap includes two axially aligned frangible seals that are affixed to the core structure in a spaced-apart relationship. The frangible seals include a foil layer and are constructed so that air passageways are formed between the frangible seals and a pipette tip when the pipette tip penetrates the frangible seals. The cap optionally includes a filter interposed between the first and second frangible seals.Type: ApplicationFiled: November 15, 2011Publication date: June 27, 2013Applicant: GEN-PROBE INCORPORATEDInventors: Daniel L. Kacian, Mark R. Kennedy, Nick M. Carter
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Patent number: 8224584Abstract: System for quantifying analyte polynucleotides employs computer-implemented analysis of real-time amplification data using a calibration curve defined by parametric equations.Type: GrantFiled: October 27, 2010Date of Patent: July 17, 2012Assignee: Gen-Probe IncorporatedInventors: James M. Carrick, Mark R. Kennedy, Jeffrey D. Chismar
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Patent number: 8218141Abstract: An apparatus and a method for optically analyzing a sample are provided. The apparatus includes a first optical device that transmits a narrow waveband of light and has a first filter and a first monochromator that provide different paths for the narrow waveband of the light. The apparatus may also include a light source that generates the light as broadband excitation light, in which case the first optical device transmits a narrow waveband of the broadband excitation light through the first filter or the first monochromator. Further, the apparatus may include a second optical device that directs the narrow waveband of the broadband excitation light onto the sample and receives emission light from the sample, a third optical device that transmits a narrow waveband of the emission light, and a detector that converts the narrow waveband of the emission light into an electrical signal.Type: GrantFiled: July 19, 2010Date of Patent: July 10, 2012Assignee: BTI Holdings, Inc.Inventors: Oleg Zimenkov, Xavier Amouretti, Robert M. Gifford, Mark R. Kennedy, Michael Kontorovich, Ben Norris, Richard N. Sears, Dan Venditti, Christopher Many
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Patent number: 8057762Abstract: A cap having a core structure dimensioned to receive a pipette therethrough. The cap includes two axially aligned frangible seals that are affixed to the core structure in a spaced-apart relationship. The frangible seals are constructed so that air passageways are formed between the frangible seals and a pipette tip when the pipette tip penetrates the frangible seals. The cap optionally includes a filter interposed between the first and second frangible seals.Type: GrantFiled: December 2, 2010Date of Patent: November 15, 2011Assignee: Gen-Probe IncorporatedInventors: Daniel L. Kacian, Mark R. Kennedy, Nick M. Carter
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Patent number: 8052944Abstract: A cap having a core structure dimensioned to receive a pipette therethrough. The cap includes two axially aligned frangible seals that are affixed to the core structure in a spaced-apart relationship. The frangible seals include a foil layer and are constructed so that air passageways are formed between the frangible seals and a pipette tip when the pipette tip penetrates the frangible seals. The cap optionally includes a filter interposed between the first and second frangible seals.Type: GrantFiled: April 1, 2010Date of Patent: November 8, 2011Assignee: Gen-Probe IncorporatedInventors: Daniel L. Kacian, Mark R. Kennedy, Nick M. Carter
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Patent number: 7927549Abstract: A method for accessing the contents of a closed collection device having a cap and a fluid-holding vessel in fixed association. The method includes penetrating one or more materials of the cap with an air displacement pipette, thereby forming one or more passageways for venting air displaced from within the collection device, where the pipette includes structure for forming the one or more passageways. A fluid present in the vessel is drawn into the pipette before the pipette is removed from the collection device.Type: GrantFiled: October 30, 2007Date of Patent: April 19, 2011Assignee: Gen-Probe IncorporatedInventors: Mordi I. Iheme, Daniel L. Kacian, Mark R. Kennedy, Gus G. Tseo, Bruce W. Anderson, Kathleen A. Dickey, Nick M. Carter
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Publication number: 20110076727Abstract: A cap having a core structure dimensioned to receive a pipette therethrough. The cap includes two axially aligned frangible seals that are affixed to the core structure in a spaced-apart relationship. The frangible seals are constructed so that air passageways are formed between the frangible seals and a pipette tip when the pipette tip penetrates the frangible seals. The cap optionally includes a filter interposed between the first and second frangible seals.Type: ApplicationFiled: December 2, 2010Publication date: March 31, 2011Applicant: GEN-PROBE INCORPORATEDInventors: Daniel L. KACIAN, Mark R. KENNEDY, Nick M. CARTER
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Publication number: 20110040490Abstract: System for quantifying analyte polynucleotides employs computer-implemented analysis of real-time amplification data using a calibration curve defined by parametric equations.Type: ApplicationFiled: October 27, 2010Publication date: February 17, 2011Applicant: GEN-PROBE INCORPORATEDInventors: James M. CARRICK, Mark R. KENNEDY, Jeffrey D. CHISMAR
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Patent number: 7831417Abstract: Method of preparing a calibration curve and determining the amount of an analyte polynucleotide present in a test sample, particularly using real-time amplification data. The method involves determining indicia of amplification for both the internal calibrator and analyte polynucleotide standards, each as a function of the amount of analyte polynucleotide standard input into the amplification reaction.Type: GrantFiled: November 14, 2006Date of Patent: November 9, 2010Assignee: Gen-Probe IncorporatedInventors: James M. Carrick, Mark R. Kennedy, Jeffrey D. Chismar
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Publication number: 20100277725Abstract: An apparatus and a method for optically analyzing a sample are provided. The apparatus includes a first optical device that transmits a narrow waveband of light and has a first filter and a first monochromator that provide different paths for the narrow waveband of the light. The apparatus may also include a light source that generates the light as broadband excitation light, in which case the first optical device transmits a narrow waveband of the broadband excitation light through the first filter or the first monochromator. Further, the apparatus may include a second optical device that directs the narrow waveband of the broadband excitation light onto the sample and receives emission light from the sample, a third optical device that transmits a narrow waveband of the emission light, and a detector that converts the narrow waveband of the emission light into an electrical signal.Type: ApplicationFiled: July 19, 2010Publication date: November 4, 2010Inventors: Oleg Zimenkov, Xavier Amouretti, Robert M. Gifford, Mark R. Kennedy, Michael Kontorovich, Ben Norris, Richard N. Sears, Dan Venditti, Christopher Many
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Patent number: 7824922Abstract: A cap which can form an essentially leak-proof seal with an open-ended vessel capable of receiving and holding fluid specimens or other materials for analysis. To minimize potentially contaminating contact between a fluid sample present in the vessel and humans or the environment, the present invention features a cap having a frangible seal which is penetrable by a plastic pipette tip or other fluid transfer device. The cap further includes a filter for limiting dissemination of an aerosol or bubbles once the frangible seal has been pierced. The filter is positioned between the frangible seal and a retaining structure. The retaining structure is positioned on the cap above the filter and may be used to contain the filter within the cap. The material of the retaining structure may be penetrable by a fluid transfer device.Type: GrantFiled: March 26, 2009Date of Patent: November 2, 2010Assignee: Gen-Probe IncorporatedInventors: Daniel L. Kacian, Mark R. Kennedy, Nick M. Carter
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Patent number: 7782454Abstract: An apparatus and a method for optically analyzing a sample are provided. The apparatus includes a first optical device that transmits a narrow waveband of light and has a first filter and a first monochromator that provide different paths for the narrow waveband of the light. The apparatus may also include a light source that generates the light as broadband excitation light, in which case the first optical device transmits a narrow waveband of the broadband excitation light through the first filter or the first monochromator. Further, the apparatus may include a second optical device that directs the narrow waveband of the broadband excitation light onto the sample and receives emission light from the sample, a third optical device that transmits a narrow waveband of the emission light, and a detector that converts the narrow waveband of the emission light into an electrical signal.Type: GrantFiled: May 25, 2007Date of Patent: August 24, 2010Assignee: BTI Holdings, Inc.Inventors: Oleg Zimenkov, Xavier Amouretti, Robert M. Gifford, Mark R. Kennedy, Michael Kontorovich, Ben Norris, Richard N. Sears, Dan Venditti, Christopher Many
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Publication number: 20100190215Abstract: A cap having a core structure dimensioned to receive a pipette therethrough. The cap includes two axially aligned frangible seals that are affixed to the core structure in a spaced-apart relationship. The frangible seals include a foil layer and are constructed so that air passageways are formed between the frangible seals and a pipette tip when the pipette tip penetrates the frangible seals. The cap optionally includes a filter interposed between the first and second frangible seals.Type: ApplicationFiled: April 1, 2010Publication date: July 29, 2010Applicant: GEN-PROBE INCORPORATEDInventors: Daniel L. KACIAN, Mark R. KENNEDY, Nick M. CARTER
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Patent number: 7691332Abstract: A cap which can form an essentially leak-proof seal with an open-ended vessel capable of receiving and holding fluid specimens or other materials for analysis. To minimize potentially contaminating contact between a fluid sample present in the vessel and humans or the environment, the present invention features a cap having a frangible seal which is penetrable by a plastic pipette tip or other fluid transfer device. The cap further includes a filter for limiting dissemination of an aerosol or bubbles once the frangible seal has been pierced. The filter is positioned between the frangible seal and a retaining structure. The retaining structure is positioned on the cap above the filter and may be used to contain the filter within the cap. The material of the retaining structure may be penetrable by a fluid transfer device.Type: GrantFiled: October 9, 2007Date of Patent: April 6, 2010Assignee: Gen-Probe IncorporatedInventors: Daniel L. Kacian, Mark R. Kennedy, Nick M. Carter
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Patent number: RE45194Abstract: A cap having a core structure dimensioned to receive a pipette therethrough. The cap includes two axially aligned frangible seals that are affixed to the core structure in a spaced-apart relationship. The frangible seals are constructed so that air passageways are formed between the frangible seals and a pipette tip when the pipette tip penetrates the frangible seals. The cap optionally includes a filter interposed between the first and second frangible seals.Type: GrantFiled: November 8, 2013Date of Patent: October 14, 2014Assignee: Gen-Probe IncorporatedInventors: Daniel L. Kacian, Mark R. Kennedy, Nick M. Carter