Patents by Inventor Mark R. Parthun

Mark R. Parthun has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Treatment of patients with chronic lymphocytic leukemia
    Patent number: 6841565
    Abstract: The invention provides methods for treating a patient with chronic lymphocytic leukemia of B cells (B-CLL). One method comprises administering to a patient with B-CLL, one or more benzamide derivatives, the benzamide derivatives including MS-275 and related compounds. Another method comprises administering to a patient with B-CLL, one or more of the benzamide derivatives, and additionally administering to the patient one or more antibodies immunospecific for 1D10 antigen. Additional methods for inducing apoptosis of B-CLL cells and for increasing expression of 1D10 antigen in B-CLL cells using the benzamide derivatives are also provided.
    Type: Grant
    Filed: March 31, 2003
    Date of Patent: January 11, 2005
    Assignee: The Ohio State University
    Inventors: David M. Lucas, Mark R. Parthun, John C. Byrd, Michael R. Grever