Patents by Inventor Mark R. Shaffar

Mark R. Shaffar has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Automated lead assay
    Patent number: 5597702
    Abstract: Detection of lead present in a sample, comprising the steps of: (a) adding a lead recovery agent to an assay solution containing lead from the sample; (b) adding to the assay solution a disulfide enzyme which is inhibited in the presence of lead; and (c) correlating the activity of the disulfide enzyme to the amount of lead in the sample. The lead recovery agent enhances the sensitivity and accuracy of the assay such that the assay can be readily automated for detection of lead in whole blood using commercially available automation systems.
    Type: Grant
    Filed: December 9, 1994
    Date of Patent: January 28, 1997
    Assignee: Abbott Laboratories
    Inventors: Martin Wong, David M. Finley, John M. Ramp, Gary L. Boltinghouse, Jr., Mark R. Shaffar, Stephen D. Stroupe, John M. Brackett
  • Luminescent assay with a reagent to alter transmitive properties of assay solution
    Patent number: 4743561
    Abstract: An improved method and reagents are disclosed for determining a ligand in an assay solution containing the ligand, a reagent system and a luminescent compounds, wherein the intensity of the light emitted by the assay solution is related to the change in the transmittive properties of the assay solution produced by the interaction of the ligand to be determined and a reagent system capable of producing a change in the transmittive properties of the assay solution in the presence of the ligand.
    Type: Grant
    Filed: March 5, 1985
    Date of Patent: May 10, 1988
    Assignee: Abbott Laboratories
    Inventor: Mark R. Shaffar
  • Fluorometric assay
    Patent number: 4495293
    Abstract: A method is provided to fluorometrically determine a ligand in an assay solution containing the ligand, reagent system and a fluorescer wherein the intensity of the fluorescer emitted by the assay solution is related to the change in the transmittive properties of the assay solution produced by the interaction of the ligand to be determined and a reagent system capable of producing a change in the transmittive properties of the assay solution in the presence of the ligand. In addition, novel reagent compositions are provided which may be utilized to either spectrophotometrically or fluorometrically determine the concentration of a ligand in an assay solution.
    Type: Grant
    Filed: February 24, 1983
    Date of Patent: January 22, 1985
    Assignee: Abbott Laboratories
    Inventor: Mark R. Shaffar
  • Method of stabilizing peroxidase in a serum protein based medium
    Patent number: 4252896
    Abstract: The addition of 8-anilino-1-napthalene sulfonic acid to a reagent comprising peroxidase in a serum protein based medium improves the stability of the enzyme 10-20 fold by blocking heme binding proteins and thereby maintaining the structural integrity of the enzyme.
    Type: Grant
    Filed: January 7, 1980
    Date of Patent: February 24, 1981
    Assignee: Abbott Laboratories
    Inventor: Mark R. Shaffar