Patents by Inventor Mark Reed

Mark Reed has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 12286754
    Abstract: Systems and methods as disclosed herein automatically provide real-time dosing corrections for an industrial process wherein enzyme blends are applied to natural fibers for pulp/paper production. An initial enzyme blend (e.g., enzymes and supporting formulation components, as relevant) and respective dose rates are selected to be applied based on expected fiber surface substrate characterization, expected fiber quality characterization, the physical conditions of the system being treated, respective characteristics of the initially selected enzyme blend components, etc. Upon application of the initial enzyme blend, online sensors provide real-time feedback data corresponding to measured actual values for the fiber surface substrate characterization and fiber quality characterization. A replacement enzyme blend (enzymes and supporting formulation components) and respective dose rates thereof is dynamically selected based on the feedback data.
    Type: Grant
    Filed: June 11, 2024
    Date of Patent: April 29, 2025
    Assignee: Buckman Laboratories International, Inc.
    Inventors: Mark Reed, Feiran Li, John Carter
  • Patent number: 12287307
    Abstract: A sensor device includes a substrate having a die attached to the substrate. The die includes an array of sensors and an array of wells cooperatively disposed over the array of sensors. The array of wells is exposed by the substrate. The sensor device further includes a flow cell secured to the substrate and defining a flow space disposed over the die and accessible to the array of wells. The flow cell defines a plurality of separate volumes. Each separate volume of the plurality of separate volumes has an inlet and an outlet. The plurality of separate volumes are separated by dividers. The dividers cover a set of wells of the array of wells.
    Type: Grant
    Filed: August 14, 2020
    Date of Patent: April 29, 2025
    Assignee: Life Technologies Corporation
    Inventors: Creighton Buie, Mark Reed, Albert Carrillo
  • Publication number: 20240390901
    Abstract: A method of applying a fluid composition to a flow cell of a sensor device includes inserting the sensor device into a holder; pipetting an aliquot of the fluid composition into a pipette tip; and applying the aliquot of the fluid composition to an opening of a fluidic connector engaged with the flow cell of the sensor device. The fluidic connector includes a body; and a plurality of fluidics interfaces formed in the body, each fluidic interface of the plurality of fluidics interfaces includes an opening, a first port in fluid communication with the opening, a second port, and a third port in fluidic communication with the second port.
    Type: Application
    Filed: August 1, 2024
    Publication date: November 28, 2024
    Inventors: Jon Hoshizaki, Mark Reed, David Marran, Patrick Leung
  • Publication number: 20240328088
    Abstract: Systems and methods as disclosed herein automatically provide real-time dosing corrections for an industrial process wherein enzyme blends are applied to natural fibers for pulp/paper production. An initial enzyme blend (e.g., enzymes and supporting formulation components, as relevant) and respective dose rates are selected to be applied based on expected fiber surface substrate characterization, expected fiber quality characterization, the physical conditions of the system being treated, respective characteristics of the initially selected enzyme blend components, etc. Upon application of the initial enzyme blend, online sensors provide real-time feedback data corresponding to measured actual values for the fiber surface substrate characterization and fiber quality characterization. A replacement enzyme blend (enzymes and supporting formulation components) and respective dose rates thereof is dynamically selected based on the feedback data.
    Type: Application
    Filed: June 11, 2024
    Publication date: October 3, 2024
    Inventors: Mark Reed, Feiran Li, John Carter
  • Publication number: 20240307871
    Abstract: A cartridge includes a housing having first and second major surfaces and defining a guide mechanism; and a plurality of containers disposed in the housing, each container of the plurality of containers having a receptacle and a lid, the lid formed of a clip and a seal, the clip to secure the seal to the receptacle, a frit disposed in the receptacle in an enclosed space defined by the receptacle and the seal, the seal having an inlet and an outlet in fluid communication with an enclosed space, the frit including a nucleotide concentrate.
    Type: Application
    Filed: May 28, 2024
    Publication date: September 19, 2024
    Inventors: Mark Reed, David Marran, Earl Zergiebel, Zheng (Derek) Xing
  • Patent number: 12076722
    Abstract: A fluidic coupler to engage a plurality of flow cells of a sensor device includes a body and a plurality of fluidics interfaces formed in the body. Each fluidic interface of the plurality of fluidics interfaces includes an opening, a first port in fluid communication with the opening, a second port, and a third port in fluidic communication with the second port.
    Type: Grant
    Filed: February 9, 2023
    Date of Patent: September 3, 2024
    Assignee: Life Technologies Corporation
    Inventors: Jon Hoshizaki, Patrick Leung, David Marran, Mark Reed
  • Publication number: 20240246082
    Abstract: A container includes a lower portion and a lid to connect with the lower portion. The lid includes a fluidic interface, a swing bar, and a counter structure disposed on an opposite side of the fluidic interface relative to the swing bar. The fluidic interface includes a first liquid port, a second liquid port, a gas port, and a seal ring disposed around the first liquid port, the second liquid port, and the gas port, the first liquid port disposed along a center axis of the container.
    Type: Application
    Filed: February 9, 2024
    Publication date: July 25, 2024
    Inventors: Mark Reed, Rui Zheng
  • Patent number: 12031273
    Abstract: Systems and methods as disclosed herein automatically provide real-time dosing corrections for an industrial process wherein enzyme blends are applied to natural fibers for pulp/paper production. An initial enzyme blend (e.g., enzymes and supporting formulation components, as relevant) and respective dose rates are selected to be applied based on expected fiber surface substrate characterization, expected fiber quality characterization, the physical conditions of the system being treated, respective characteristics of the initially selected enzyme blend components, etc. Upon application of the initial enzyme blend, online sensors provide real-time feedback data corresponding to measured actual values for the fiber surface substrate characterization and fiber quality characterization. A replacement enzyme blend (enzymes and supporting formulation components) and respective dose rates thereof is dynamically selected based on the feedback data.
    Type: Grant
    Filed: December 7, 2021
    Date of Patent: July 9, 2024
    Assignee: Buckman Laboratories International, Inc.
    Inventors: Mark Reed, Feiran Li, John Carter
  • Publication number: 20240182965
    Abstract: A sequencing system includes an automated sequencing instrument adapted to determine variant calls for one or more extracted polynucleotide samples with a performance of at least 98.5% raw read accuracy and a run time in a range of 5 hours to 14 hours to determine variant calls for 4 extracted polynucleotide samples using a targeted assay with one DNA pool per sample and an average amplicon size in a range of 100 to 120 bases.
    Type: Application
    Filed: February 9, 2024
    Publication date: June 6, 2024
    Inventors: Mark Reed, Chiu Tai Andrew Wong, David Marran
  • Patent number: 11998910
    Abstract: In an example, a method for preparing a nucleotide solution includes flowing an aqueous solution from an initial solution storage of a sequencing instrument continuously through a container fluidically coupled to the sequencing instrument, the container comprising a nucleotide concentrate; and collecting the aqueous solution with nucleotide in a storage container.
    Type: Grant
    Filed: August 26, 2021
    Date of Patent: June 4, 2024
    Assignee: Life Technologies Corporation
    Inventors: Mark Reed, Zheng (Derek) Xing, David Marran, Earl Zergiebel
  • Patent number: 11904321
    Abstract: A container includes a lower portion and a lid to connect with the lower portion. The lid includes a fluidic interface, a swing bar, and a counter structure disposed on an opposite side of the fluidic interface relative to the swing bar. The fluidic interface includes a first liquid port, a second liquid port, a gas port, and a seal ring disposed around the first liquid port, the second liquid port, and the gas port, the first liquid port disposed along a center axis of the container.
    Type: Grant
    Filed: May 28, 2020
    Date of Patent: February 20, 2024
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Mark Reed, Rui Zheng
  • Patent number: 11905558
    Abstract: A sequencing system includes an automated sequencing instrument adapted to determine variant calls for one or more extracted polynucleotide samples with a performance of at least 98.5% raw read accuracy and a run time in a range of 5 hours to 14 hours to determine variant calls for 4 extracted polynucleotide samples using a targeted assay with one DNA pool per sample and an average amplicon size in a range of 100 to 120 bases.
    Type: Grant
    Filed: August 14, 2020
    Date of Patent: February 20, 2024
    Assignee: Life Technologies Corporation
    Inventors: Mark Reed, Chiu Tai Andrew Wong, David Marran
  • Publication number: 20230226548
    Abstract: A fluidic coupler to engage a plurality of flow cells of a sensor device includes a body and a plurality of fluidics interfaces formed in the body. Each fluidic interface of the plurality of fluidics interfaces includes an opening, a first port in fluid communication with the opening, a second port, and a third port in fluidic communication with the second port.
    Type: Application
    Filed: February 9, 2023
    Publication date: July 20, 2023
    Inventors: Jon HOSHIZAKI, Patrick LEUNG, David MARRAN, Mark REED
  • Patent number: 11590499
    Abstract: An apparatus includes a fluidic coupler including an opening. A first port is in fluid communication with the opening and is to interface with an inlet of a flow cell of a sensor device. A second port is to interface with an outlet of the flow cell of the sensor device. A third port is in fluidic communication with the second port. The apparatus further includes a mechanical assembly moveable between a first position and a second position. The fluidic coupler is secured to the flow cell of the sensor device in the first position. The fluidic coupler is disengaged from the flow cell of the sensor device in the second position.
    Type: Grant
    Filed: August 14, 2020
    Date of Patent: February 28, 2023
    Assignee: LIFE TECHNOLOGIES CORPORATION
    Inventors: Jon Hoshizaki, Patrick Leung, David Marran, Mark Reed
  • Publication number: 20230051201
    Abstract: A chargeable atomic battery (CAB) includes a plurality of CAB units and a CAB housing to hold the plurality of CAB units. Each of the CAB units are formed of a precursor compact including precursor material particles embedded inside an encapsulation material. The precursor material particles include a precursor kernel formed of a precursor material that is initially manufactured in a stable state and convertible into an activated material that is an activated state via atomic irradiation by a particle radiation source. Upon the precursor material being converted, the precursor material is in a partially depleted state such that an initial portion of the precursor material is depleted and a recharge portion of the precursor material is convertible into the activated state via atomic irradiation by the particle radiation source for recharging the chargeable atomic battery.
    Type: Application
    Filed: February 7, 2021
    Publication date: February 16, 2023
    Inventors: Michael John Eades, Christopher Morrison, Paolo Francesco Venneri, Wesley Deason, Mark Reed
  • Publication number: 20230024338
    Abstract: A nuclear reactor core includes a plurality of fuel elements and a skewed-pin moderator block array of skewed-pin moderator blocks to form a nuclear reactor core inner portion and a nuclear reactor core outer portion. The nuclear reactor core inner portion includes an inner moderator matrix formed of a plurality of inner holes that include a plurality of inner fuel openings with one or more fuel elements disposed therein. The plurality of inner holes further include a plurality of inner coolant passages to flow a coolant. The nuclear reactor core outer portion includes an outer moderator matrix formed of a plurality of outer holes that include a plurality of outer fuel openings with one or more fuel elements disposed therein. The plurality of outer holes further include a plurality of outer coolant passages to flow the coolant. The inner holes are irregularly spaced with respect to the outer holes.
    Type: Application
    Filed: January 25, 2021
    Publication date: January 26, 2023
    Inventors: Mark Reed, Michael John Eades, Paolo Francesco Venneri, Vishal Patel, Wesley Deason, Richard J. Kapernick
  • Publication number: 20220226819
    Abstract: A fluidic device holder configured to orient a fluidic device. The device holder includes a support structure configured to receive a fluidic device. The support structure includes a base surface that faces in a direction along the Z-axis and is configured to have the fluidic device positioned thereon. The device holder also includes a plurality of reference surfaces facing in respective directions along an XY-plane. The device holder also includes an alignment assembly having an actuator and a movable locator arm that is operatively coupled to the actuator. The locator arm has an engagement end. The actuator moves the locator arm between retracted and biased positions to move the engagement end away from and toward the reference surfaces. The locator arm is configured to hold the fluidic device against the reference surfaces when the locator arm is in the biased position.
    Type: Application
    Filed: April 5, 2022
    Publication date: July 21, 2022
    Inventors: Erik Williamson, Bryan Crane, Patrick Leung, Drew Verkade, Mark Reed
  • Publication number: 20220205033
    Abstract: A method for determining a sequence of nucleic acids includes purifying the nucleic acids from a sample with a purification instrument in accordance with a purification plan of a run plan. The purified nucleic acids are disposed in a transfer plate. Disposition of the purified nucleic acids is stored in a transfer file. The method further includes transferring the transfer plate to a sequencing instrument; transferring the transfer file to the sequencing instrument; and sequencing the nucleic acids with the sequencing instrument in accordance with a sequencing plan of the run plan and based on the transfer file.
    Type: Application
    Filed: December 16, 2021
    Publication date: June 30, 2022
    Inventors: Mark REED, Joseph PODHASKY, Shanti SHANKAR
  • Publication number: 20220186441
    Abstract: Systems and methods as disclosed herein automatically provide real-time dosing corrections for an industrial process wherein enzyme blends are applied to natural fibers for pulp/ paper production. An initial enzyme blend (e.g., enzymes and supporting formulation components, as relevant) and respective dose rates are selected to be applied based on expected fiber surface substrate characterization, expected fiber quality characterization, the physical conditions of the system being treated, respective characteristics of the initially selected enzyme blend components, etc. Upon application of the initial enzyme blend, online sensors provide real-time feedback data corresponding to measured actual values for the fiber surface substrate characterization and fiber quality characterization. A replacement enzyme blend (enzymes and supporting formulation components) and respective dose rates thereof is dynamically selected based on the feedback data.
    Type: Application
    Filed: December 7, 2021
    Publication date: June 16, 2022
    Inventors: Mark Reed, Feiran Li, John Carter
  • Publication number: 20220176369
    Abstract: A system includes a pipetting system including a 3-axis gantry; a sled mechanism to select a magnetic comb from a set of magnetic combs; a fluorometer; and a set of receptacles to receive welled plates. A method for purifying nucleic acids includes applying a sample to a well of a multi-well plate, selecting a magnetic comb from a set of magnetic combs disposed on a gantry system, collecting magnetic beads using the magnetic comb, collecting nucleic acid using the magnetic beads, and eluting the nucleic acid from the beads.
    Type: Application
    Filed: November 15, 2021
    Publication date: June 9, 2022
    Inventors: Joseph PODHASKY, Mark Reed, Nathan Kane