Patents by Inventor Mark Richard Redfern

Mark Richard Redfern has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • vectored vaccines against and methods of use
    Patent number: 8703153
    Abstract: The invention provides an attenuated Salmonella vaccine vector comprising one or more heterologous polynucleotides that encode immunogenic Chlamydial peptides. In one embodiment, the attenuated Salmonella vaccine vector comprises aroC and ssaV attenuating mutations. The heterologous polynucleotides encoding the immunogenic Chlamydial peptides can be under the control of an inducible promoter such as a Salmonella ssaG promoter. In one embodiment of the invention, the immunogenic Chlamydial peptide is a PmpG peptide, for instance, a CT110, CT84 or CT40 peptide.
    Type: Grant
    Filed: June 16, 2009
    Date of Patent: April 22, 2014
    Inventors: Jonathan Lewis Telfer, Mark Richard Redfern, Michael Joseph Lacy
  • USE OF E. COLI SURFACE ANTIGEN 3 SEQUENCES FOR THE EXPORT OF HETEROLOGOUS ANTIGENS
    Publication number: 20120064114
    Abstract: The present invention provides an export signal system based on E. coli CS3 antigen for directing the secretion of foreign antigens from host cells. In particular, the invention describes genetic constructs encoding fusion proteins that contain a CS3 export signal fused to at least one heterologous amino acid sequence. Attenuated microorganisms expressing the fusion proteins and pharmaceutical compositions comprising such attenuated microorganisms are also disclosed.
    Type: Application
    Filed: October 21, 2009
    Publication date: March 15, 2012
    Applicant: Emergent Product Development United Kingdom
    Inventors: Jonathan Telfer, Mark Richard Redfern
  • SALMONELLA VECTORED VACCINES AGAINST CHLAMYDIA AND METHODS OF USE
    Publication number: 20110268760
    Abstract: The invention provides an attenuated Salmonella vaccine vector comprising one or more heterologous polynucleotides that encode immunogenic Chlamydial peptides. In one embodiment, the attenuated Salmonella vaccine vector comprises aroC and ssaV attenuating mutations. The heterologous polynucleotides encoding the immunogenic Chlamydial peptides can be under the control of an inducible promoter such as a Salmonella ssaG promoter. In one embodiment of the invention, the immunogenic Chlamydial peptide is a PmpG peptide, for instance, a CT110, CT84 or CT40 peptide.
    Type: Application
    Filed: June 16, 2009
    Publication date: November 3, 2011
    Inventors: Jonathan Lewis Telfer, Mark Richard Redfern, Michael Joseph Lacy