Abstract: This disclosure provides modulators of Cystic Fibrosis Transmembrane Conductance Regulator (CFTR) having core structure (I), pharmaceutical compositions containing at least one such modulator, methods of treatment of CFTR mediated diseases, including cystic fibrosis, using such modulators and pharmaceutical compositions, combination pharmaceutical compositions and combination therapies employing those modulators, and processes and intermediates for making such modulators.

Abstract: A golf club head and golf club having large head dimensions, and large face characteristics, as well as unique mass property attributes driven by relationships not often considered in conventional club head design, to achieve a resistance to squaring the club head during a golf swing that is comfortable to the novice golfer, while increasing stability during off-center impacts and obtaining preferred launch characteristics. This is achieved in part via establishing a club head configuration and associated weight distribution to yield a center of gravity location that results in a preferred magnitude of Delta1 and Delta2 values, CG angle, moments of inertia, and associated ratios, relationships, and club head mass property characteristics influenced by these variables to achieve improved performance.

Abstract: In various embodiments, an energy storage mounting system includes an inverter wall bracket mounted to a wall, wherein an inverter is coupled to the inverter wall bracket. The system includes a battery wall bracket to which a battery block is coupled. The battery wall bracket interfaces with an auxiliary bracket that is mounted to the wall, is vertically translatable relative to the auxiliary bracket, and is at least in part ground-supported. The battery block is electrically connected to the inverter.

Abstract: The invention provides a dosage form and a bolus configured for administration to an animal, wherein said dosage form and said bolus is configured to release a methane inhibitor to the animal over a period of time. Preferably the methane inhibitor is a haloform. Also provided is the use of the bolus of the invention to reduce methane production in a ruminant animal. Also provided is the method of manufacturing a bolus of the invention.

Abstract: The present disclosure provides methods and systems for detecting multiple different nucleotides in a sample. In particular, the disclosure provides for detection of multiple different nucleotides in a sample utilizing fewer detection moieties than the number of nucleotides being detected and/or fewer imaging events than the number of nucleotides being detected.

Abstract: One or more structures and/or methods are provided. In an example of the subject matter presented herein, an apparatus includes a circuit board, a first component mounted to the circuit board, a shielding structure mounted to the circuit board and having a first platform elevated over the circuit board, and a semiconductor die mounted to the first platform, wherein the shielding structure is between the first component and the semiconductor die.

Abstract: Techniques for aligning object representations for animation include analyzing a source object representation and a target object representation to identify a category of the source object and a category of the target object. Based on the category or categories of the objects, a feature extraction machine learning models is selected. The source object representation and the target object representation are provided as input to the selected feature extraction machine learning model to generate respective semantic descriptors and shape vectors for the source and target objects. Based on the semantic descriptors and the shape vectors for the source and target objects, an alignment machine learning model generates an aligned target object representation that is aligned with the source object representation and usable for animating the target object.

Abstract: The present system ensures that external noise sources do not taint sensor data recorded about a user's sleep parameters, to reduce false positives and false negatives, and provides a more accurate record of the user's sleep sounds, by cycling on and off noise sources. Additionally, the present system, in one embodiment, may be used to track changes in sound patterns from the user and from the environment. This may lead to early warning of health issues, as well as issues with the devices in the bedroom.

Abstract: An energy storage system includes an energy storage component. It further includes heat generating electronics. It further includes a fluid circulator that transfers fluid between the energy storage component and the heat generating electronics. The circulator is controlled to alternatively transfer fluid from the battery to the heat generating electronics or from the heat generating electronics to the energy storage component based at least in part on a thermal state of the energy storage system.

Abstract: An example of an apparatus to transport utility-scale lithium-ion batteries in a racked and operational state. The apparatus includes a base and an isolation platform. In addition, the apparatus includes an isolator mounted on the base to support the isolation platform. The isolator is to dampen forces exerted on the isolation platform from the base. Furthermore, the apparatus includes a rack mounted onto the isolation platform. The rack is to secure a plurality of lithium-ion batteries to store energy at a utility-scale to be provided to a power distribution network. The plurality of lithium-ion batteries is racked in an operational state during transportation.

Abstract: Devices, systems and methods that track various aspects of a person's sleep and environment to optimize one or more aspects of the user's environment and sleep conditions, quality and duration, together or alone, and help make the one or more users maintain and prolong his or her deep sleep status and improve the their sleep duration and quality.

Abstract: Video sources and inertial sensors are attached to a weapon and to goggles. A computer receives video images from the weapon- and goggles-mounted sources and inertial data from the sensors. The computer calculates a location for an image from the weapon-mounted source within an image from the goggles-mounted source using the inertial sensor data. The sensor-based location is checked (and possibly adjusted) based on a comparison of the images. A database contains information about real-world objects in a field of view of the goggles-mounted source, and is used to generate icons or other graphics concerning such objects.

Abstract: A golf club head is provided with an electronic display that is visible to a user of the golf club head when the golf club head is in the address position, such as for displaying one or more images to the user. The electronic display may include a memory, a microprocessor, and a battery, and may be configured to communicate with a user operable electronic device via a wired or a wireless communication protocol. For example, the electronic display may be configured to receive one or more images from the user operable electronic device, to store the one or more images in the memory, and to display the one or more images to the user.

Abstract: Methods, apparatus, systems and articles of manufacture are disclosed to determine the number of people at a location. An example apparatus includes a configuration changer to change a configuration setting of the base station to cause mobile devices to register with the base station, a registration manager to respond to registration requests received from the mobile devices after the configuration setting is changed by storing device identification information for the corresponding mobile devices, and a counter controller to identify a number of the mobile devices at a location of the base station based on the stored device identification information.

Abstract: A cooking exhaust hood system, that has an exhaust hood adapted to be located over at least one cooking appliance and an exhaust fan connected to the exhaust hood, with the exhaust fan having a controllable exhaust air flow volume. A camera monitors a surface of the at least one cooking appliance and provide an image signal representing a visual status of the at least one cooking appliance. An image processing controller is connected to an image database and is configured to receive the image signal and to compare the visual status of the at least one cooking appliance based on the image signal to stored images in the image database. The image processing controller then output a cooking appliance status signal. An exhaust fan controller is provided that is connected to the exhaust fan. The exhaust fan controller is configured to receive the cooking appliance status signal and adjusts the exhaust fan accordingly.

Abstract: A method of synchronising audio content arranged to be played by a second device with video content played by a first device, wherein the second device includes a camera, comprises: capturing at least a portion of the video content with the camera; performing image recognition on the captured video content to identify a set time point in the audio content; and commencing playing the audio content from a selected time point in the audio content corresponding to the set time point, such that the audio content is synchronous with the video content. A method of pre-preparing video content for use in such a synchronisation method is also described.

Abstract: A rotating linear adjustment bracket (RLAB) for use in providing connective support between construction building materials and a ground mounted pier includes a base plate mounted to a sleeve. The RLAB includes one or more gussets bridging the base to the sleeve to increase its strength. A bracket is then attached to the base plate for connecting various construction materials to the base plate. The bracket can be configured in various sizes and shapes as needed for attachment to the building construction materials.

Abstract: A wiring harness for a battery and inverter system includes a main cable. It further includes an inverter connector configured to plug the main cable into an inverter module. It further includes a first spur of the main cable terminating in a first-type battery device connector. It further includes a second spur of the main cable terminating in a second type battery device connector.

Abstract: The present invention includes systems and methods for a continuous-wave (CW) radar system for detecting, geolocating, identifying, discriminating between, and mapping ferrous and non-ferrous metals in brackish and saltwater environments. The radar system (e.g., the CW radar system) generates multiple extremely low frequency (ELF) electromagnetic waves simultaneously and uses said waves to detect, locate, and classify objects of interest. These objects include all types of ferrous and non-ferrous metals, as well as changing material boundary layers (e.g., soil to water, sand to mud, rock to organic materials, water to air, etc.). The radar system (e.g., the CW radar system) is operable to detect objects of interest in near real time.