Patents by Inventor Mark Roach

Mark Roach has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions of Stable Tiacumicins
    Publication number: 20130065844
    Abstract: The present invention is related to pharmaceutical compositions of one or more tiacumicins that exhibit improved stability, and methods of treatment using such formulations. The formulations contain one or more tiacumicins, such as difimicin, and one or more antioxidants, such as butylated hydroxytoluene, and, optionally, one or more pharmaceutically acceptable excipients.
    Type: Application
    Filed: March 9, 2012
    Publication date: March 14, 2013
    Inventors: Suketu Sanghvi, Mark Roach, Joseph F. Zhou, Eric Michael Mittleberg, Ping He
  • Compositions of stable tiacumicins
    Publication number: 20080176927
    Abstract: The present invention is related to pharmaceutical compositions of one or more tiacumicins that exhibit improved stability, and methods of treatment using such formulations. The formulations contain one or more tiacumicins, such as difimicin, and one or more antioxidants, such as butylated hydroxytoluene, and, optionally, one or more pharmaceutically acceptable excipients.
    Type: Application
    Filed: January 14, 2008
    Publication date: July 24, 2008
    Applicant: Optimer Pharmaceuticals, Inc.
    Inventors: Suketu Sanghvi, Mark Roach, Joseph F. Zhou, Eric Michael Mittleberg, Ping He
  • Antisense modulation of MEKK4 expression
    Publication number: 20060019920
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of MEKK4. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding MEKK4. Methods of using these compounds for modulation of MEKK4 expression and for treatment of diseases associated with expression of MEKK4 are provided.
    Type: Application
    Filed: July 11, 2005
    Publication date: January 26, 2006
    Inventors: C. Bennett, Susan Freier, Brett Monia, Nicholas Dean, Hong Zhang, Robert McKay, Donna Ward, William Gaarde, Jacqueline Wyatt, Andrew Watt, Rosanne Crooke, Mark Graham, Pamela Nero, Kenneth Dobie, Alexander Borchers, Eric Marcusson, Mark Roach
  • Antisense modulation of p70 S6 kinase expression
    Publication number: 20050267063
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of p70 S6 kinase. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding p70 S6 kinase. Methods of using these compounds for modulation of p70 S6 kinase expression and for treatment of diseases associated with expression of p70 S6 kinase are provided.
    Type: Application
    Filed: April 27, 2005
    Publication date: December 1, 2005
    Inventors: C. Bennett, Brett Monia, Susan Freier, Brenda Baker, William Gaarde, Erich Koller, Susan Murray, Andrew Watt, Jacqueline Wyatt, Pamela Nero, Mark Roach, Lex Cowsert, Kenneth Dobie
  • Antisense modulation of TFAP2C expression
    Publication number: 20050227938
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of TFAP2C. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding TFAP2C. Methods of using these compounds for modulation of TFAP2C expression and for treatment of diseases associated with expression of TFAP2C are provided.
    Type: Application
    Filed: December 17, 2004
    Publication date: October 13, 2005
    Inventors: C. Bennett, Brenda Baker, Nicholas Dean, Brett Monia, Susan Freier, James Karras, Hong Zhang, Susan Murray, Madeline Butler, Erich Koller, Thomas Condon, William Gaarde, Andrew Watt, Mark Graham, Jacqueline Wyatt, Lex Cowsert, Kenneth Dobie, Mark Roach
  • Antisense modulation of sterol regulatory element-binding protein-1 expression
    Publication number: 20050215504
    Abstract: Antisense compounds, compositions and methods are provided for modulating the expression of sterol regulatory element-binding protein-1. The compositions comprise antisense compounds, particularly antisense oligonucleotides, targeted to nucleic acids encoding sterol regulatory element-binding protein-1. Methods of using these compounds for modulation of sterol regulatory element-binding protein-1 expression and for treatment of diseases associated with expression of sterol regulatory element-binding protein-1 are provided.
    Type: Application
    Filed: December 16, 2004
    Publication date: September 29, 2005
    Inventors: C. Bennett, Susan Freier, Nicholas Dean, Brett Monia, William Gaarde, James Karras, Hong Zhang, Robert McKay, Donna Ward, Lex Cowsert, Erich Koller, Jacqueline Wyatt, Mark Roach, Andrew Watt, Brenda Baker, Kenneth Dobie